Commercial cell-based therapies for musculoskeletal injuries in horses.
Abstract: Several cell-based therapeutic options to treat musculoskeletal injuries in horses are commercially available. The current literature supports the use of cell-based therapies to treat equine musculoskeletal injuries. Researchers continue to search for more effective cell-based therapies to provide practitioners with optimal treatment tools for musculoskeletal injuries in horses. Cell-based therapies require specialized facilities and technical competencies that might not be available or economically justifiable in many private practices. This review provides a summary of current commercially available cell-based therapeutic products for equine applications, their similarities and differences, and current objective data relating to their clinical efficacy.
Copyright © 2011 Elsevier Inc. All rights reserved.
Publication Date: 2011-06-12 PubMed ID: 21872764DOI: 10.1016/j.cveq.2011.04.001Google Scholar: Lookup
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- Journal Article
- Review
Summary
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The research article discusses various cell-based therapeutic options that are commercially available to treat musculoskeletal injuries in horses. The study reviews these products, highlighting their similarities and differences, and provides data on their clinical efficacy.
Background
- The study revolves around the understanding and the application of cell-based therapies in treating musculoskeletal injuries in horses. There is sufficient scientific literature that supports the effectiveness of these therapies.
Current Research
- Research is being continuously conducted to discover and develop more effective cell-based therapies. These efforts aim to equip practitioners with more efficient tools to manage musculoskeletal injuries in horses.
Challenges
- Despite the promise of these therapies, their application does pose certain challenges. They require specialized facilities and a high level of technical knowledge. These requirements, unfortunately, may not be economical or feasible for many private practices, which can limit their widespread use.
Review Objective
- This particular review has been designed to provide a comprehensive summary of the currently available commercial cell-based therapeutic products designed for equine applications. It focuses on comparing these products, pointing out their similarities and differences.
- The research paper also aims to present objective data relating to the clinical efficacy of these treatments. This is important to provide clarity on how successfully these therapies can cure musculoskeletal injuries in horses.
Cite This Article
APA
Gutierrez-Nibeyro SD.
(2011).
Commercial cell-based therapies for musculoskeletal injuries in horses.
Vet Clin North Am Equine Pract, 27(2), 363-371.
https://doi.org/10.1016/j.cveq.2011.04.001 Publication
Researcher Affiliations
- Department of Clinical Veterinary Medicine, College of Veterinary Medicine, University of Illinois, 1008 West Hazelwood Drive, Champaign-Urbana, IL 61802, USA. sgn@illinois.edu
MeSH Terms
- Animals
- Cell Transplantation / veterinary
- Horse Diseases / therapy
- Horses
- Musculoskeletal Diseases / therapy
- Musculoskeletal Diseases / veterinary
Citations
This article has been cited 9 times.- Ferreira LVO, Kamura BDC, Oliveira JPM, Chimenes ND, Carvalho M, Santos LAD, Dias-Melicio LA, Amorim RL, Amorim RM. In Vitro Transdifferentiation Potential of Equine Mesenchymal Stem Cells into Schwann-Like Cells. Stem Cells Dev 2023 Jul;32(13-14):422-432.
- Shirzeyli MH, Tayyebiazar A, Aliakbari F, Ghasemi F, Eini F, Shirzeyli FH, Vanaki E, Sobhani A. Comparison of the efficacy of bone morphogenetic protein-4 on in vitro differentiation of murine adipose and bone marrow mesenchymal stem cells into primordial germ cells. Res Pharm Sci 2022 Apr;17(2):123-133.
- Menarim BC, MacLeod JN, Dahlgren LA. Bone marrow mononuclear cells for joint therapy: The role of macrophages in inflammation resolution and tissue repair. World J Stem Cells 2021 Jul 26;13(7):825-840.
- Salcedo-Jiménez R, Koenig JB, Lee OJ, Gibson TWG, Madan P, Koch TG. Extracorporeal Shock Wave Therapy Enhances the In Vitro Metabolic Activity and Differentiation of Equine Umbilical Cord Blood Mesenchymal Stromal Cells. Front Vet Sci 2020;7:554306.
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