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Comparative immunology, microbiology and infectious diseases1990; 13(3); 127-136; doi: 10.1016/0147-9571(90)90275-x

Comparative features of retroviral infections of livestock.

Abstract: Retroviral infections of livestock have become of increasing importance due to their usefulness as comparative models for human retroviral infections and their effects upon animal health and marketability of animals and animal products nationally and internationally. This paper presents a perspective on the retroviruses of economic concern in veterinary medicine with emphasis on the importance of understanding the modes of virus transmission and the species specificity of the viruses. The retroviruses reviewed include the oncovirus, bovine leukosis virus, and the lentiviruses, equine infectious anemia virus; maedi/visna virus, caprine arthritis-encephalitis virus and bovine visna-like virus. The comparative features amongst these animal retroviruses and those of humans must be recognized by the veterinary and medical professions since the similarities in virus replication and spread by blood transfer can provide important clues in controlling and perhaps preventing human retroviruses infections, such as the human immunodeficiency virus.
Publication Date: 1990-01-01 PubMed ID: 1963391DOI: 10.1016/0147-9571(90)90275-xGoogle Scholar: Lookup
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  • Comparative Study
  • Journal Article
  • Research Support
  • U.S. Gov't
  • P.H.S.
  • Review

Summary

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This research article explores the relevance and impact of retroviral infections in livestock, particularly on their health and subsequent marketability. It emphasises on studying transmission modes, species-specificity of the viruses and draws parallels between livestock retroviruses and human retroviruses to improve control strategies for human retrovirus infections.

Overview of Retroviral Infections in Livestock

  • The study emphasizes the importance of understanding retroviral infections in livestock, particularly observing their similarities to human retroviruses.
  • The main impetus behind this research is the potential for these infections to impact animal health and the marketability of livestock and related products on a domestic and international scale.
  • The paper suggests that livestock retroviral infections could be advantageous models for studying human retroviral infections, potentially offering key insights for medical researchers.

Specific Retroviruses Highlighted

  • The paper goes into detail on specific viruses of concern in veterinary medicine, including the “oncovirus,” bovine leukosis virus, and a variety of lentiviruses such as the equine infectious anemia virus, maedi/visna virus, caprine arthritis-encephalitis virus, and bovine visna-like virus.
  • Each of these viruses carries its own set of concerns in relation to livestock health and economics. Moreover, their comparative features might parallel certain characteristics in human retroviruses, making them particularly valuable for study.

In-depth Look at Transmission and Species-Specificity

  • The article not only outlines the potential dangers of these retroviruses but also delves into the modes of transmission, highlighting the importance of understanding how these viruses are specifically spread.
  • It also emphasizes the concept of species-specificity, asserting that different retroviruses might affect different species in a variety of ways. This could be critical information when planning intervention strategies or treatments.

Implications for Human Retroviral Infections

  • The paper strongly advocates for the veterinary and medical professions to acknowledge the similarities between animal and human retroviruses, asserting that this awareness could lead to improvements in controlling, and even preventing, human retroviral infections.
  • Such an approach could potentially lead to breakthroughs in understanding human conditions like the human immunodeficiency virus (HIV), using the similarities in virus replication and transmission methods as potential sources of information.

Cite This Article

APA
Evermann JF. (1990). Comparative features of retroviral infections of livestock. Comp Immunol Microbiol Infect Dis, 13(3), 127-136. https://doi.org/10.1016/0147-9571(90)90275-x

Publication

ISSN: 0147-9571
NlmUniqueID: 7808924
Country: England
Language: English
Volume: 13
Issue: 3
Pages: 127-136

Researcher Affiliations

Evermann, J F
  • Department of Veterinary Clinical Medicine and Surgery, College of Veterinary Medicine, Washington State University, Pullman 99164-6610.

MeSH Terms

  • Animals
  • Animals, Domestic
  • Arthritis-Encephalitis Virus, Caprine / physiology
  • Disease Models, Animal
  • Humans
  • Infectious Anemia Virus, Equine / physiology
  • Leukemia Virus, Bovine / immunology
  • Retroviridae Infections / microbiology
  • Retroviridae Infections / transmission
  • Retroviridae Infections / veterinary
  • Visna-maedi virus / physiology

Citations

This article has been cited 5 times.
  1. Langemeier JL, Cook SJ, Cook RF, Rushlow KE, Montelaro RC, Issel CJ. Detection of equine infectious anemia viral RNA in plasma samples from recently infected and long-term inapparent carrier animals by PCR.. J Clin Microbiol 1996 Jun;34(6):1481-7.
  2. Darcel C. Lymphoid leukosis viruses, their recognition as 'persistent' viruses and comparisons with certain other retroviruses of veterinary importance.. Vet Res Commun 1996;20(1):83-108.
    doi: 10.1007/BF00346580pubmed: 8693704google scholar: lookup
  3. Hanson J, Hydbring E, Olsson K. A long term study of goats naturally infected with caprine arthritis-encephalitis virus.. Acta Vet Scand 1996;37(1):31-9.
    doi: 10.1186/BF03548117pubmed: 8659344google scholar: lookup
  4. Darcel C. Reflections on scrapie and related disorders, with consideration of the possibility of a viral aetiology.. Vet Res Commun 1995;19(3):231-52.
    doi: 10.1007/BF01839302pubmed: 7571397google scholar: lookup
  5. Whetstone CA, Sayre KR, Dock NL, VanDerMaaten MJ, Miller JM, Lillehoj E, Alexander SS. Examination of whether persistently indeterminate human immunodeficiency virus type 1 Western immunoblot reactions are due to serological reactivity with bovine immunodeficiency-like virus.. J Clin Microbiol 1992 Apr;30(4):764-70.
    doi: 10.1128/jcm.30.4.764-770.1992pubmed: 1315332google scholar: lookup