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The Veterinary record2021; 188(3); e5; doi: 10.1002/vetr.5

Comparison of liberal and goal-directed fluid therapy after small intestinal surgery for strangulating lesions in horses.

Abstract: There are few guidelines for the appropriate mode of fluid administration during and after colic surgery, and is challenging to reach the right balance while avoiding overhydration. This study aimed to compare goal-directed fluid therapy (GDFT) and 'liberal' fluid regimens (LFRs) in horses undergoing small intestinal surgery. Methods: Eighteen horses subjected to small intestinal surgery were matched according to the surgical lesion, type of anastomosis, length of resection, and duration of clinical signs. Horses in the LFR group were administered intravenous (IV) fluids for at least 24 h. In the GDFT group, IV fluids were administered only when considered necessary based on clinical parameters. Postoperative reflux (POR), packed cell volume, total protein, heart rate, venous lactate level, complications, and long-term survival rates were compared. Results: Three horses in the LFR and one in the GDFT group developed POR. Horses in the GDFT group had a shorter time interval to first oral water intake and shorter hospitalisation time. Postoperative complication rates and survival were not different between groups. Conclusions: Further studies are necessary to set guidelines for the evaluation of hydration status and to plan postoperative fluid administration; however, GDFT may be a valid alternative to liberal fluid therapy after colic surgery.
© 2021 British Veterinary Association.
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Publication Date: 2021-10-16 PubMed ID: 34651880DOI: 10.1002/vetr.5Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study is an analysis of the effectiveness of two fluid therapy methods, goal-directed fluid therapy (GDFT) and liberal fluid therapy (LFR), in horses after they have undergone small intestinal surgery. The research highlights that there is a need for more study before specific guidelines can be outlined, but suggests that goal-directed fluid therapy may be a valid option.

Research Methodology

  • The study involved 18 horses that underwent small intestinal surgery. The selection was on the basis of parameters like the type of surgical lesion, type of anastomosis, length of resection, and duration of clinical signs.
  • The horses were divided into two groups. One group followed the liberal fluid therapy method (LFR), where they were administered intravenous (IV) fluids for at least 24 hours.
  • The other group followed the goal-directed fluid therapy (GDFT) method. Here, fluids were administered only when deemed necessary based on clinical parameters.
  • The researchers made comparison of postoperative reflux, packed cell volume, total protein, heart rate, venous lactate level, complications, and long-term survival rates amongst the two groups.

Research Findings

  • In the group that followed LFR, three horses developed postoperative reflux, while in the GDFT group, only one horse had this issue.
  • The results showed that horses in the GDFT group had a shorter time interval to the first oral water intake, as well as a shorter hospitalisation time.
  • However, there was no significant difference in postoperative complication rates and survival between the two groups.

Conclusion

  • The study concludes that there is a need for further research to establish definitive guidelines for evaluating hydration status and planning postoperative fluid administration in horses that have undergone small intestinal surgery.
  • Nevertheless, the findings suggest that goal-directed fluid therapy (GDFT) could be a viable alternative to liberal fluid therapy.

Cite This Article

APA
Giusto G, Vercelli C, Gandini M. (2021). Comparison of liberal and goal-directed fluid therapy after small intestinal surgery for strangulating lesions in horses. Vet Rec, 188(3), e5. https://doi.org/10.1002/vetr.5

Publication

The Veterinary record
ISSN: 2042-7670
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 188
Issue: 3
Pages: e5

Researcher Affiliations

Giusto, Gessica
  • Department of Veterinary Sciences of Turin, University of Turin, Turin, Italy.
Vercelli, Cristina
  • Department of Veterinary Sciences of Turin, University of Turin, Turin, Italy.
Gandini, Marco
  • Department of Veterinary Sciences of Turin, University of Turin, Turin, Italy.

MeSH Terms

  • Animals
  • Colic / surgery
  • Colic / veterinary
  • Digestive System Surgical Procedures / veterinary
  • Fluid Therapy / veterinary
  • Goals
  • Horse Diseases / surgery
  • Horses
  • Postoperative Complications / veterinary

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Citations

This article has been cited 4 times.
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    doi: 10.3390/ani13061107pubmed: 36978647google scholar: lookup
  2. Gomez DE, Kopper JJ, Byrne DP, Renaud DL, Schoster A, Dunkel B, Arroyo LG, Mykkanen A, Gilsenan WF, Pihl TH, Lopez-Navarro G, Tennent-Brown BS, Hostnik LD, Mora-Pereira M, Marques F, Gold JR, DeNotta SL, Desjardins I, Stewart AJ, Kuroda T, Schaefer E, Oliver-Espinosa OJ, Agne GF, Uberti B, Veiras P, Delph Miller KM, Gialleti R, John E, Toribio RE. Treatment approaches to horses with acute diarrhea admitted to referral institutions: A multicenter retrospective study. PLoS One 2024;19(11):e0313783.
    doi: 10.1371/journal.pone.0313783pubmed: 39565809google scholar: lookup
  3. Gao M, Chen M, Dai G, Zhu D, Cai Y. Clinical study: the impact of goal-directed fluid therapy on volume management during enhanced recovery after surgery in gastrointestinal procedures. Acta Biochim Pol 2024;71:12377.
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