Comparison of radiographic and computed tomographic images of the lungs in healthy neonatal foals.
Abstract: To compare CT and radiographic images of the lungs in sedated healthy foals positioned in sternal recumbency and to investigate whether a relationship exists between CT-derived measurements of lung attenuation and Paco2 and Pao2. Methods: 6 healthy Standardbred foals < 14 days of age. Methods: Thoracic CT images were acquired followed by radiographic views with each foal sedated and positioned in sternal recumbency. For each foal, both CT and radiographic images were evaluated for severity and extent of changes by lung regions on the basis of a subjective scoring system by 3 investigators. Quantitative analysis of CT images was also performed. Assessments of Pao2 and Paco2 were performed before sedation, following sedation prior to CT, and after CT prior to radiography. Results: Interobserver agreement for CT and radiographic image scoring was strong (0.73) and fair (0.65), respectively; intraobserver agreement was near perfect for CT (0.97) and radiographic (0.94) image scoring. Increased CT attenuation and radiographic changes were identified for all foals and were preferentially distributed in the caudoventral portion of the lungs. Radiographic scores were significantly lower than CT image scores. A positive correlation (r = 0.872) between lung attenuation and CT image score was identified. A significant increase in Paco2 was not considered clinically relevant. Significant changes in Pao2 were not observed. Conclusions: Results suggested that interpretation of CT images may be less subjective, compared with interpretation of radiographic images. These findings may aid in the evaluation of CT and radiographic images of neonatal foals with respiratory tract disease.
Publication Date: 2014-12-24 PubMed ID: 25535660DOI: 10.2460/ajvr.76.1.42Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
- Anatomy
- Clinical Findings
- Clinical Pathology
- Clinical Study
- Comparative Study
- Computed Tomography
- Diagnosis
- Diagnostic Imaging
- Diagnostic Technique
- Disease Diagnosis
- Equine Health
- Foals
- Horses
- Imaging Techniques
- Lung Health
- Physiology
- Radiology
- Respiratory Health
- Standardbred Horses
- Veterinary Medicine
- Veterinary Research
Summary
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This research focuses on a comparison of different imaging techniques, specifically computed tomographic (CT) images and radiographic images, of the lungs in healthy newborn foals, aiming to determine if there’s a connection between measurements of lung attenuation from the CT images and the gas levels in the blood (Paco2 and Pao2).
Study Design and Methods
- The study involved six healthy Standardbred foals all under 14 days old.
- Both thoracic CT images and radiographic views were acquired from each foal while they were sedated and positioned in sternal recumbency (lying on their chest)
- The CT and radiographic images were evaluated for changes or abnormalities in the lung regions. This assessment was made using a subjective scoring system by three separate investigators.
- A quantitative analysis was also conducted on the CT images.
- To investigate any relationship between lung attenuation and gas levels in blood, measurements of Pao2 and Paco2 were performed before sedation, after sedation but before the CT, and after the CT but before radiography.
Study Findings
- There was strong interobserver agreement for CT image scoring of 0.73, and a fair agreement for radiographic image scoring of 0.65.
- Intraobserver agreement was near perfect for both CT (0.97) and radiographic (0.94) image scoring.
- All the foals showed increased CT attenuation and radiographic changes. These changes were largely concentrated in the caudoventral portion of the lungs.
- Radiographic scores were significantly lower than CT image scores.
- A strong positive correlation (r = 0.872) between lung attenuation and CT image score was observed.
- A minor increase in Paco2 was noted but was not considered clinically relevant, while no significant changes in Pao2 were detected.
Study Conclusions
- The results suggested that interpreting CT images is less subjective than interpreting radiographic images.
- This study’s findings may assist in the evaluation of CT and radiographic images of young foals suffering from respiratory tract disease.
Cite This Article
APA
Schliewert EC, Lascola KM, O'Brien RT, Clark-Price SC, Wilkins PA, Foreman JH, Mitchell MA, Hartman SK, Kline KH.
(2014).
Comparison of radiographic and computed tomographic images of the lungs in healthy neonatal foals.
Am J Vet Res, 76(1), 42-52.
https://doi.org/10.2460/ajvr.76.1.42 Publication
Researcher Affiliations
- Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802.
MeSH Terms
- Animals
- Animals, Newborn / physiology
- Blood Gas Analysis / veterinary
- Female
- Horses / physiology
- Lung / diagnostic imaging
- Lung / growth & development
- Lung / physiology
- Male
- Posture
- Radiography, Thoracic / veterinary
- Reference Values
- Tomography, X-Ray Computed / veterinary
Citations
This article has been cited 4 times.- Raidal SL, Catanchin M, Sacks M, Carstens A, Quinn C, Mosing M. Effects of 2 modes of positive pressure ventilation on respiratory mechanics and gas exchange in foals.. J Vet Intern Med 2023 May-Jun;37(3):1233-1242.
- Kozłowska N, Wierzbicka M, Jasiński T, Domino M. Advances in the Diagnosis of Equine Respiratory Diseases: A Review of Novel Imaging and Functional Techniques.. Animals (Basel) 2022 Feb 4;12(3).
- Arencibia A, Corbera JA, Ramírez G, Díaz-Bertrana ML, Pitti L, Morales M, Jaber JR. Anatomical Assessment of the Thorax in the Neonatal Foal Using Computed Tomography Angiography, Sectional Anatomy, and Gross Dissections.. Animals (Basel) 2020 Jun 17;10(6).
- Sprayberry KA. Ultrasonographic Examination of the Equine Neonate: Thorax and Abdomen.. Vet Clin North Am Equine Pract 2015 Dec;31(3):515-43.
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