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The Veterinary clinics of North America. Equine practice2025; 41(3); 473-493; doi: 10.1016/j.cveq.2025.08.002

Complications in Equine Anesthesia.

Abstract: General anesthesia in equine patients is associated with a higher risk of mortality despite improved monitoring equipments and anesthetic techniques most likely due to their large body size, unique physiology and anatomy, behavioral tendencies, and therefore the challenging recovery. Larger body mass, increased age, higher American Society of Anesthesiologists (ASA) status, out-of-hours surgery, and longer duration of anesthesia have been identified as contributing factors increasing the risk of perioperative mortality in equine patients. Especially the recovery period remains a critical time in equine anesthesia. With vigilant monitoring and timely therapeutic support, intra-anesthetic complications can be quickly identified and managed, ultimately leading to improved outcomes.
Publication Date: 2025-09-26 PubMed ID: 41015719DOI: 10.1016/j.cveq.2025.08.002Google Scholar: Lookup
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Summary

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Overview

  • This research article discusses the challenges and risks associated with general anesthesia in horses, emphasizing factors that contribute to complications and the importance of careful monitoring to improve outcomes.

Introduction to Equine Anesthesia Risks

  • General anesthesia in horses carries a higher risk of mortality compared to many other animals.
  • This elevated risk persists despite advances in monitoring equipment and anesthetic techniques.
  • Factors unique to horses contribute to this risk, including their large body size, unique physiological and anatomical characteristics, and behavioral tendencies.
  • The recovery phase after anesthesia is particularly critical and poses significant challenges.

Contributing Factors to Increased Mortality

  • Large Body Size: Horses’ size influences anesthesia management difficulties, making the process more complex and increasing complication risks.
  • Unique Physiology and Anatomy: Specific physiological traits and anatomical features of horses create challenges in circulation, respiratory management, and drug metabolism during anesthesia.
  • Behavioral Tendencies: Horses’ natural tendencies, such as the strong fight-or-flight response, can complicate both anesthesia and recovery.
  • Age: Increased age is associated with higher perioperative risk in horses due to declining physiological reserves and possible preexisting conditions.
  • ASA Status: Higher American Society of Anesthesiologists (ASA) physical status indicates poorer pre-anesthetic condition, correlating with increased anesthesia risk.
  • Timing of Surgery: Procedures performed outside regular hours (e.g., nights or weekends) have been linked to higher risks, possibly due to staffing or resource limitations.
  • Duration of Anesthesia: Longer anesthesia times increase exposure to anesthetic drugs and stress on the body, raising the likelihood of complications.

Challenges During Recovery

  • The recovery period after anesthesia is especially vulnerable for horses and is considered a critical phase.
  • Due to their size and behavior, horses can injure themselves during recovery if not properly supported.
  • Effective management includes continuous, vigilant monitoring to detect any complications early.
  • Timely therapeutic interventions during recovery can significantly improve the chances of a safe outcome.

Importance of Monitoring and Therapeutic Support

  • Close intra-anesthetic monitoring helps identify complications such as cardiovascular or respiratory instability quickly.
  • Monitoring allows anesthetists to adjust drug dosages and supportive care in real time.
  • Prompt therapeutic support during both the anesthetic and recovery phases reduces the risk of death and morbidity.
  • Implementation of comprehensive protocols tailored to horse-specific anatomy and physiology enhances patient safety.

Conclusion

  • Despite technological advances, equine anesthesia remains high-risk due to multiple intrinsic and extrinsic factors.
  • Understanding these risks and focusing on meticulous monitoring and management throughout anesthesia and recovery is key for improving survival and recovery quality in equine patients.

Cite This Article

APA
Cremer J, Ross J, Paranjape V. (2025). Complications in Equine Anesthesia. Vet Clin North Am Equine Pract, 41(3), 473-493. https://doi.org/10.1016/j.cveq.2025.08.002

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 41
Issue: 3
Pages: 473-493
PII: S0749-0739(25)00045-8

Researcher Affiliations

Cremer, Jeannette
  • Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Skip Bertman Drive, Baton Rouge, LA 70803, USA. Electronic address: jcremer@lsu.edu.
Ross, Juliet
  • Virginia Veterinary Centers, 4300 Greybull Drive, Henrico, VA 23233, USA.
Paranjape, Vaidehi
  • Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 215 Duck Pond Drive, Blacksburg, VA 24061, USA.

MeSH Terms

  • Animals
  • Horses
  • Horse Diseases / surgery
  • Anesthesia, General / veterinary
  • Anesthesia, General / adverse effects
  • Postoperative Complications / veterinary
  • Anesthesia / veterinary
  • Anesthesia / adverse effects
  • Intraoperative Complications / veterinary

Conflict of Interest Statement

Disclosures The authors have nothing to disclose.

Citations

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