COMPUTED TOMOGRAPHIC APPEARANCE OF MELANOMAS IN THE EQUINE HEAD: 13 CASES.
Abstract: Melanomas are one of the most common neoplasms in the horse and are frequently found in the head region. There is a genetic predisposition in horses with a gray hair coat. Computed tomography (CT) is frequently used in referral practice to evaluate the equine head but there are few reports describing the CT appearance of melanomas in this location. The aim of this retrospective, case series study was to describe characteristics in a group of horses with confirmed disease. Case records from two referral hospitals were reviewed, and 13 horses were identified that had undergone CT of the head, with a diagnosis of melanoma based on cytology, histopathology, or visual assessment of black (melanotic) tissue. A median of 11 melanomas was identified per horse (range 3-60), with a total of 216 masses. Melanomas were found most frequently in the parotid salivary gland, guttural pouches, surrounding the larynx and pharynx and adjacent to the hyoid apparatus. In noncontrast CT images, all melanomas were hyperattenuating (median; 113.5 Hounsfield units (HU), IQR; 26 HU) compared to masseter musculature (median; 69 HU, IQR; 5.5 HU). Fifty-six (25.9%) masses were partially mineralized and 41 (19.4%) included hypoattenuating areas. Histopathological assessment of these melanomas suggested that the hyperattenuation identified was most likely a result of abundant intracytoplasmic melanin pigment. Melanomas of the equine head appeared to have consistent CT features that aided detection of mass lesions and their distribution, although histopathological analysis or visual confirmation should still be obtained for definitive diagnosis.
© 2016 American College of Veterinary Radiology.
Publication Date: 2016-01-22 PubMed ID: 26799704DOI: 10.1111/vru.12345Google Scholar: Lookup
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- Journal Article
Summary
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The research study focuses on the use of Computed Tomography (CT) to observe the characteristics of melanomas, a common type of tumor, in horses’ heads. The study investigates the physical properties of these tumors using CT images obtained from thirteen horses and explores the locations where the tumors are most often found.
Methodology
- For the study, the researchers examined the previous case records from two referral hospitals.
- They selected 13 horses that had undergone CT scans of the head and had been diagnosed with melanoma based on cytology, histopathology, or direct visual identification of black tissue (indicative of melanotic melanoma).
- During the course of the study, they recorded the number of melanomas in each horse, noting a median of 11 tumors per horse (with a range of 3 to 60). The total number of tumors found among the 13 horses was 216.
Findings
- The researchers found that the melanomas were commonly located in the parotid salivary gland, guttural pouches, around the larynx and pharynx, and next to the hyoid apparatus.
- When examining the non-contrast CT images, they found that the melanomas were hyperattenuating, meaning they appear brighter on the images compared to the surrounding masseter musculature.
- They also found that a large portion (25.9%) of the tumors were partially mineralized, and a significant number (19.4%) included hypoattenuating areas, indicating uneven density within those tumors.
- Upon histopathological assessment, the researchers determined that the strong attenuation observed in the images was likely due to large amounts of melanin pigment within the tumor cells.
Conclusions
- The study concludes that melanomas in the head of horses exhibit consistent features on CT scans that can assist in identifying these tumors and determining their locations.
- However, the researchers also emphasized the importance of confirmatory histopathological analysis or direct visual identification for a definitive diagnosis of melanoma.
Cite This Article
APA
Dixon J, Smith K, Perkins J, Sherlock C, Mair T, Weller R.
(2016).
COMPUTED TOMOGRAPHIC APPEARANCE OF MELANOMAS IN THE EQUINE HEAD: 13 CASES.
Vet Radiol Ultrasound, 57(3), 246-252.
https://doi.org/10.1111/vru.12345 Publication
Researcher Affiliations
- Department of Clinical Sciences and Services, The Royal Veterinary College, Hawkshead Lane, Hatfield, AL9 7TA, UK.
- Department of Clinical Sciences and Services, The Royal Veterinary College, Hawkshead Lane, Hatfield, AL9 7TA, UK.
- Department of Clinical Sciences and Services, The Royal Veterinary College, Hawkshead Lane, Hatfield, AL9 7TA, UK.
- Bell Equine Veterinary Clinic, Butchers Lane, Mereworth, Kent, ME18 5GS, UK.
- Bell Equine Veterinary Clinic, Butchers Lane, Mereworth, Kent, ME18 5GS, UK.
- Department of Clinical Sciences and Services, The Royal Veterinary College, Hawkshead Lane, Hatfield, AL9 7TA, UK.
MeSH Terms
- Animals
- Female
- Head and Neck Neoplasms / diagnostic imaging
- Head and Neck Neoplasms / veterinary
- Horse Diseases / diagnostic imaging
- Horses
- Male
- Melanoma / diagnostic imaging
- Melanoma / veterinary
- Retrospective Studies
- Tomography, X-Ray Computed / veterinary
Citations
This article has been cited 5 times.- Nourinezhad J, Abdi A, Moarabi A, Hanafi MG, Fatahian Dehkordi RA, Tomańska A. Major Salivary Gland Examinations of the Donkey (Equus asinus) Using Sectional Anatomy, Computed Tomography and Magnetic Resonance Imaging. Vet Med Sci 2025 May;11(3):e70298.
- Zscherpe P, Kalbitz J, Weber LA, Paschke R, Mäder K, von Rechenberg B, Cavalleri JV, Meißner J, Klein K. Potent drug delivery enhancement of betulinic acid and NVX-207 into equine skin in vitro - a comparison between a novel oxygen flow-assisted transdermal application device and microemulsion gels. BMC Vet Res 2024 May 16;20(1):202.
- Stieger-Vanegas SM, Hanna AL. The Role of Computed Tomography in Imaging Non-neurologic Disorders of the Head in Equine Patients. Front Vet Sci 2022;9:798216.
- Bregger MDK, Koch C, Zimmermann R, Sangiorgio D, Schweizer-Gorgas D. Cone-beam computed tomography of the head in standing equids. BMC Vet Res 2019 Aug 13;15(1):289.
- Le Roux C, Venter FJ, Kirberger RM. Cervical porcupine quill foreign body involving the spinal cord of a dog: A description of various imaging modality findings. J S Afr Vet Assoc 2017 Dec 8;88(0):e1-e7.
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