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Journal of animal science2002; 80(1); 79-83; doi: 10.2527/2002.80179x

Conditioning taste aversions to locoweed (Oxytropis sericea) in horses.

Abstract: Locoweed (Oxytropis sericea) is a serious poisoning problem for horses grazing on infested rangelands in the western United States. Our objectives were to determine 1) whether lithium chloride or apomorphine would condition aversions to palatable foods, and at what doses, and 2) whether horses could be averted to fresh locoweed in a pen and grazing situation. Apomorphine was not an acceptable aversive agent because at the dose required to condition an aversion (> or = 0.17 mg/kg BW), apomorphine induced unacceptable behavioral effects. Lithium chloride given via stomach tube at 190 mg/kg BW conditioned strong and persistent aversions to palatable feeds with minor signs of distress. Pen and grazing tests were conducted in Colorado to determine if horses could be averted to fresh locoweed. Pen tests indicated that most horses (5/6) were completely averted from locoweed. Treated horses ate 34 g of fresh locoweed compared to 135 g for controls (P < 0.01) during three pen tests when offered 150 g per test. One horse (T) in the treatment group ate locoweed each time it was offered in the pen, but ate no locoweed while grazing. In the grazing trial, control horses averaged 8.6% of bites of locoweed (P < 0.01) during the grazing portion of the study, whereas treated horses averaged <0.5%. One treated horse (S) accounted for all consumption; he consumed 15% of his bites as locoweed in a grazing bout on d 2 of the field study. Thereafter, he was dosed a second time with lithium chloride and ate no locoweed in the subsequent 5 d. Three of six horses required two pairings of lithium chloride with fresh locoweed to condition a complete aversion. The results of this study indicate that horses can be averted from locoweed using lithium chloride as an aversive agent, and this may provide a management tool to reduce the risk of intoxication for horses grazing locoweed-infested rangeland.
Publication Date: 2002-02-08 PubMed ID: 11831531DOI: 10.2527/2002.80179xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research article discusses a study into methods of preventing horses from consuming locoweed, a plant poisonous to them, by conditioning aversion using substances like lithium chloride or apomorphine.

Research Objectives

  • This research was undertaken with two primary objectives in mind:
    • To ascertain whether the administration of lithium chloride or apomorphine could trigger distaste towards delicious foods in horses, and at what doses this effect could be achieved.
    • To investigate if horses could be discouraged from consuming fresh locoweed in a controlled setting and while grazing.

Key Findings

  • Apomorphine was discarded as a viable aversive agent due to the unacceptable behavioral effects it produced in horses, even at the minimum dose required to initiate an aversion.
  • Lithium chloride, however, was found to be effective in creating strong and lasting aversions to palatable feeds in horses, with only minor signs of distress noted. Administered via a stomach tube, a dosage of 190 mg/kg body weight was used.’
  • In pen tests conducted, it was found that most horses (5 out of 6) completely refrained from consuming locoweed. The treated horses consumed significantly less locoweed compared to the controls.
  • In a grazing situation, one treated horse continued to eat locoweed when offered in the pen but refrained from doing so while grazing. The overall locoweed consumption by the control horses was considerably higher than that of the treated horses.
  • One treated horse, who initially consumed a significant percentage of locoweed, required a second dose of lithium chloride before it stopped eating the weed altogether.

Conclusion

  • The study results conclusively show that lithium chloride can be used effectively as an aversive agent, conditioning horses against locoweed consumption. This could offer a valuable tool for managing the risk of poisoning in horses grazing on locoweed-infested land.

Cite This Article

APA
Pfister JA, Stegelmeier BL, Cheney CD, Ralphs MH, Gardner DR. (2002). Conditioning taste aversions to locoweed (Oxytropis sericea) in horses. J Anim Sci, 80(1), 79-83. https://doi.org/10.2527/2002.80179x

Publication

ISSN: 0021-8812
NlmUniqueID: 8003002
Country: United States
Language: English
Volume: 80
Issue: 1
Pages: 79-83

Researcher Affiliations

Pfister, J A
  • USDA-ARS Poisonous Plant Research Laboratory, Logan, UT 84341, USA. jpfister@cc.usu.edu
Stegelmeier, B L
    Cheney, C D
      Ralphs, M H
        Gardner, D R

          MeSH Terms

          • Animals
          • Apomorphine / pharmacology
          • Astragalus Plant / poisoning
          • Aversive Therapy
          • Behavior, Animal / physiology
          • Conditioning, Psychological
          • Dose-Response Relationship, Drug
          • Feeding Behavior / physiology
          • Food Preferences
          • Horse Diseases / prevention & control
          • Horses / physiology
          • Horses / psychology
          • Housing, Animal
          • Lithium Chloride / pharmacology
          • Plant Poisoning / prevention & control
          • Plant Poisoning / veterinary
          • Random Allocation
          • Taste / physiology

          Citations

          This article has been cited 2 times.
          1. Rørvang MV, Nielsen BL, McLean AN. Sensory Abilities of Horses and Their Importance for Equitation Science.. Front Vet Sci 2020;7:633.
            doi: 10.3389/fvets.2020.00633pubmed: 33033724google scholar: lookup
          2. Wang Y, Li Y, Hu Y, Li J, Yang G, Kang D, Li H, Wang J. Potential degradation of swainsonine by intracellular enzymes of Arthrobacter sp. HW08.. Toxins (Basel) 2013 Nov 14;5(11):2161-71.
            doi: 10.3390/toxins5112161pubmed: 24240642google scholar: lookup