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Journal of veterinary internal medicine2007; 21(4); 812-819; doi: 10.1892/0891-6640(2007)21[812:capcvc]2.0.co;2

Confirmed and presumptive cervical vertebral compressive myelopathy in older horses: a retrospective study (1992-2004).

Abstract: Cervical vertebral compressive myelopathy (CVCM) is a common cause of myelopathy in horses aged 6 months to 4 years. Little information is available regarding the types of lesions, treatment, and outcomes in horses with CVCM that are > or =4 years old. Methods: Twenty-two affected horses (10 with a confirmed diagnosis of CVCM and 12 presumptive cases) and 210 contemporaneous control horses. Methods: Horses > or =4 years old that were diagnosed with CVCM between January 1992 and January 2004 were identified from medical records at Texas A&M University and the University of Florida. Data analyzed included history, signalment, neurologic examination findings, lesion location, treatment, and outcome. Signalment was also recorded in a population of contemporaneous controls. Results: Horses identified had a median age of 8.4 years, and there was a greater percentage of male horses among the cases than among the controls. The most common breeds represented were warmblood (n=6) and quarter horse (n=5) types; warmbloods were significantly (P < .05) overrepresented relative to control horses. The caudal cervical vertebral column was the most common site of CVCM lesions, and the C5-C6 (4/9) and C6-C7 (3/9) articulations were most often identified as abnormal via myelography. The most common lesions seen with radiography and myelography were articular process osteophytes. Of the 22 affected horses, 8 were euthanized and a diagnosis of CVCM was confirmed by necropsy for all; 5 of 8 of these horses had spinal cord compression caused, entirely or in part, by articular process osteophytes. Medical management was the therapy chosen in all horses, and administration of corticosteroids and nonsteroidal anti-inflammatory drugs resulted in improvement in the greatest number of horses. Conclusions: CVCM should be a differential diagnosis in older horses with cervical myelopathy. Articular process osteophytes are the most frequently identified cause of spinal cord compression in this group. Male horses and horses of warmblood or Tennessee Walking Horse breeds may be predisposed to this condition.
Publication Date: 2007-08-22 PubMed ID: 17708404DOI: 10.1892/0891-6640(2007)21[812:capcvc]2.0.co;2Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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This research focuses on a detailed study of cervical vertebral compressive myelopathy (CVCM) in horses, specifically the types of lesions, treatments, and outcomes in horses that are more than four years old. It provides valuable insights on the commonality of the disease, the predominant breeds affected, and the most effective treatment methods.

Methodology

  • The study analyzed data from 22 horses diagnosed with CVCM, including 10 confirmed and 12 presumptive cases, and an additional 210 control horses.
  • Horses older than 4 years diagnosed between 1992 and 2004 were included in the study. The information was collected from medical records at Texas A&M University and the University of Florida.
  • Data such as history, signalment (age, breed, sex), neurologic examination findings, lesion location, treatment, and outcome were critically evaluated.

Results

  • The median age of the diagnosed horses was roughly 8.4 years and a higher proportion of the cases were males compared to the controls.
  • The most frequent breeds represented were warmbloods and quarter horses. Warmbloods were significantly more affected by CVCM compared to other breeds.
  • Cervical vertebral column, particularly C5-C6 and C6-C7 articulations were identified as the most common sites of CVCM lesions.
  • The most frequent lesions identified during radiography and myelography were articular process osteophytes – bone spurs on the spinal joints.
  • During the study, eight horses were euthanized and CVCM was confirmed at necropsy in all the cases; 63% among them had spinal cord compression resulting partly or entirely from articular process osteophytes.

Treatment and Conclusion

  • All affected horses were medically managed; administration of corticosteroids and non-steroidal anti-inflammatory drugs led to significant improvements in the majority of cases.
  • The research concluded that CVCM should be an important differential diagnosis in older horses with neural disorders along the spine.
  • Articular process osteophytes were identified as the most prevalent cause of spinal cord compression in the group.
  • Male horses, and warmblood or Tennessee Walking Horse breeds may be predisposed to this condition.

Cite This Article

APA
Levine JM, Adam E, MacKay RJ, Walker MA, Frederick JD, Cohen ND. (2007). Confirmed and presumptive cervical vertebral compressive myelopathy in older horses: a retrospective study (1992-2004). J Vet Intern Med, 21(4), 812-819. https://doi.org/10.1892/0891-6640(2007)21[812:capcvc]2.0.co;2

Publication

ISSN: 0891-6640
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 21
Issue: 4
Pages: 812-819

Researcher Affiliations

Levine, Jonathan M
  • Department of Small Animal Clinical Sciences , College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station 77843, USA. jlevine@cvm.tamu.edu
Adam, Emma
    MacKay, Robert J
      Walker, Michael A
        Frederick, Jeremy D
          Cohen, Noah D

            MeSH Terms

            • Animals
            • Cervical Vertebrae / pathology
            • Horse Diseases / diagnosis
            • Horse Diseases / pathology
            • Horse Diseases / therapy
            • Horses
            • Retrospective Studies
            • Spinal Cord Compression / diagnosis
            • Spinal Cord Compression / pathology
            • Spinal Cord Compression / therapy
            • Spinal Cord Compression / veterinary