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Animal science journal = Nihon chikusan Gakkaiho2018; 90(2); 222-228; doi: 10.1111/asj.13057

Dietary effect of lemon verbena extract on selected blood parameters and on plasma oxidative profile in Avelignese horses.

Abstract: The effect of Lippia citriodora extract on selected blood parameters and on plasma oxidative markers in Avelignese horses was evaluated. Twenty-four horses were divided into three groups, consisting of eight animals each. Results of two experimental groups, 0.5 mg of verbascoside per kg of metabolic body weight (bw ) in the low-dose group (LVB) and 1.0 mg of verbascoside per kg of metabolic body weight (bw ) in the high-dose group (HVB), were compared to the control group (CON). Groups fed L. citriodora extract (HVB and LVB) showed a significant decrease in triglycerides, total cholesterol and LDL cholesterol (p < .01), bilirubin, and transaminases (p < .05), and an increase in HDL cholesterol (p < .01) compared to the CON group. Oxidative status was improved due to significant decrease in plasma concentration of ROMs and TBARS (p < .01) and increase in levels of vitamin A and vitamin E (p < .01). Based on obtained results, it is assumed that dietary supplementation with L. citriodora extract might find a useful application in horse feeding, with positive impact observed in blood parameters and plasma oxidative markers, with beneficial effects on the physiological welfare of livestock animals.
Publication Date: 2018-12-16 PubMed ID: 30556324DOI: 10.1111/asj.13057Google Scholar: Lookup
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  • Journal Article

Summary

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The research article examines how the addition of Lippia citriodora extract, commonly known as lemon verbena, to the diets of Avelignese horses affects their blood parameters and oxidative markers in plasma, suggesting potential benefits for the animals’ health.

Study Overview

The study involved splitting twenty-four Avelignese horses into three group, each consisting of eight horses. Two groups were experimental, differing in the dose of Lippia citriodora extract fed, while the third served as the control group, not receiving any extract. The goal of this experiment was to analyze the impact of the lemon verbena extract.

Treatment Groups

  • The low-dose group (LVB) received 0.5 mg of verbascoside per kg of metabolic body weight.
  • The high-dose group (HVB) was given 1.0 mg of verbascoside per kg of metabolic body weight.
  • The control group (CON) did not receive any extract in their diet and were used for comparison.

Effects on Blood Parameters and Oxidative Markers

The two groups of horses that were fed with L. citriodora extract showed substantial improvements in blood parameters and oxidative markers in their plasma. Key changes observed included:

  • A decrease in triglycerides, total cholesterol, LDL cholesterol, bilirubin, and transaminases.
  • An increase in HDL cholesterol.
  • Improvement in oxidative status, demonstrated by a decrease in plasma concentration of ROMS and TBARS, and an increase in levels of vitamins A and E.

Conclusion

The findings indicate that dietary supplementation involving L. citriodora extract can have beneficial effects on the physiological welfare of livestock animals, showing positive impacts on horses’ blood parameters and plasma oxidative markers. It therefore suggests potential uses for lemon verbena extract within horse feeding regimes that could improve their health and wellbeing.

Cite This Article

APA
Palazzo M, Vizzarri F, Cinone M, D'Alessandro AG, Martemucci G, Casamassima D. (2018). Dietary effect of lemon verbena extract on selected blood parameters and on plasma oxidative profile in Avelignese horses. Anim Sci J, 90(2), 222-228. https://doi.org/10.1111/asj.13057

Publication

ISSN: 1740-0929
NlmUniqueID: 100956805
Country: Australia
Language: English
Volume: 90
Issue: 2
Pages: 222-228

Researcher Affiliations

Palazzo, Marisa
  • Department of Agricultural, Environmental and Food Sciences, University of Molise, Campobasso, Italy.
Vizzarri, Francesco
  • Department of Agricultural, Environmental and Food Sciences, University of Molise, Campobasso, Italy.
Cinone, Mario
  • Department of Emergency and Organ Transplants, University of Bari, Bari, Italy.
D'Alessandro, Angela Gabriella
  • Department of Agricultural and Environmental Science, University of Bari, Bari, Italy.
Martemucci, Giovanni
  • Department of Agricultural and Environmental Science, University of Bari, Bari, Italy.
Casamassima, Donato
  • Department of Agricultural, Environmental and Food Sciences, University of Molise, Campobasso, Italy.

MeSH Terms

  • Animal Feed
  • Animals
  • Bilirubin / blood
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Diet / veterinary
  • Dietary Supplements
  • Dose-Response Relationship, Drug
  • Horses / blood
  • Horses / metabolism
  • Lippia
  • Oxidation-Reduction
  • Oxidative Stress
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology
  • Transaminases / blood
  • Triglycerides / blood
  • Vitamin A / blood
  • Vitamin E / blood

Citations

This article has been cited 4 times.
  1. Quaresma M, Marín C, Bacellar D, Nóvoa M, Navas FJ, McLean A. Selenium and Vitamin E Concentrations in Miranda Jennies and Foals (Equus asinus) in Northeast Portugal. Animals (Basel) 2021 Jun 14;11(6).
    doi: 10.3390/ani11061772pubmed: 34198534google scholar: lookup
  2. Angiolillo A, Leccese D, Palazzo M, Vizzarri F, Casamassima D, Corino C, Di Costanzo A. Effects of Lippia citriodora Leaf Extract on Lipid and Oxidative Blood Profile of Volunteers with Hypercholesterolemia: A Preliminary Study. Antioxidants (Basel) 2021 Mar 27;10(4).
    doi: 10.3390/antiox10040521pubmed: 33801586google scholar: lookup
  3. Liu A, Zhu Y, Yang S, Yao B, Liao F, Zhu B. Dietary verbena officinalis reduces feather-pecking duration in laying ducks by modulating cecal microbiota composition and hypothalamic neurotransmitter secretion. Front Microbiol 2025;16:1605305.
    doi: 10.3389/fmicb.2025.1605305pubmed: 40584029google scholar: lookup
  4. Rossi R, Mainardi E, Vizzarri F, Corino C. Verbascoside-Rich Plant Extracts in Animal Nutrition. Antioxidants (Basel) 2023 Dec 24;13(1).
    doi: 10.3390/antiox13010039pubmed: 38247465google scholar: lookup