Dietary risk factors and colonic pH and mineral concentrations in horses with enterolithiasis.
Abstract: A prospective, unmatched case control study was performed to identify dietary and environmental risk factors for enterolithiasis in horses in California and to determine whether colonic ingesta analyses differed between horses with and without enteroliths. Forty-three horses with enterolithiasis were compared with 19 horses with surgical colic attributable to nonstrangulating obstruction of the colon without enteroliths. Colonic ingesta samples were collected at surgery from horses with enteroliths and control horses. Colonic pH and colonic concentrations of magnesium, phosphorus, sulfur, sodium, calcium, potassium, and nitrogen were measured. Questionnaires were distributed to owners to determine diet and management practices. Student's t-test and Mann-Whitney tests were used to evaluate differences in pH, dry matter content, percent nitrogen, and mineral content. Associations between dietary and management risk factors and enterolith occurrence were quantified by odds ratios. Mean pH of colonic contents from horses with enterolithiasis was significantly higher than for control horses. Horses with enterolithiasis had significantly lower percent dry matter in colonic fecal samples and higher mean mineral concentrations than controls. On the basis of reported feeding and management practices, horses with enterolithiasis were fed a significantly higher proportion of alfalfa in their diet and were less likely to have daily access to pasture grass than horses without enteroliths. Results suggest that decreasing alfalfa consumption and allowing daily access to pasture grazing might reduce the risk of enterolithiasis. Dietary modifications promoting acidification of colonic contents and dilution of minerals might be beneficial as preventive measures for enterolithiasis in horses.
Publication Date: 2004-06-11 PubMed ID: 15188822DOI: 10.1892/0891-6640(2004)18<346:drfacp>2.0.co;2Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The article discusses a study that compared diet and environmental factors between horses in California with enterolithiasis (intestinal stones) and horses with surgical colic due to non-strangulating obstruction of the colon. The results suggest reducing alfalfa consumption and promoting regular access to pasture grass might decrease the likelihood of enterolithiasis.
Research Design and Methodology
- The researchers performed a prospective, unmatched case control study. In this kind of study, the researchers observe subjects and measure their outcomes without having to manipulate environments or behaviors.
- Two groups were compared – 43 horses with enterolithiasis, and 19 horses with surgical colic due to nonstrangulating obstruction of the colon but without enteroliths.
- Colonic ingesta samples were collected from the horses during surgery. These samples were analysed for their pH level and concentrations of various minerals – magnesium, phosphorus, sulfur, sodium, calcium, potassium, and nitrogen.
- Questionnaires were sent to horse owners to gather information on the horses’ diets and management practices.
- Statistical tests, such as the Student’s t-test and Mann-Whitney tests, were used to compare the values such as pH, dry matter content, nitrogen percentage, and mineral content between the two groups.
Study Findings
- The study found that horses with enterolithiasis had significantly higher mean pH levels in their colonic contents than the control group.
- The dry matter percentage in fecal samples of horses with enterolithiasis was found to be significantly lower than in the controls.
- Mineral concentrations in the horses with enterolithiasis were higher on average than in the control group.
- Regarding diet and management practices, horses with enterolithiasis were found to have consumed higher proportions of alfalfa in their diet and were less likely to have daily access to pasture grass compared to horses without enteroliths.
Conclusions and Recommendations
- The findings suggest that reducing alfalfa intake and providing daily access to pasture grazing could decrease the risk of enterolithiasis in horses.
- Additionally, dietary modifications that promote acidification of the colonic contents and dilution of minerals were suggested as potential preventive measures for enterolithiasis.
Cite This Article
APA
Hassel DM, Rakestraw PC, Gardner IA, Spier SJ, Snyder JR.
(2004).
Dietary risk factors and colonic pH and mineral concentrations in horses with enterolithiasis.
J Vet Intern Med, 18(3), 346-349.
https://doi.org/10.1892/0891-6640(2004)18<346:drfacp>2.0.co;2 Publication
Researcher Affiliations
- Comparative Gastroenterology Laboratory, Department of Surgical and Radiological Scieinces, School of Veterinary Medicine, University of California, Davis, CA, USA. dmhassel@ucdavis.edu
MeSH Terms
- Animal Feed / adverse effects
- Animals
- Case-Control Studies
- Colon / physiology
- Diet
- Gastrointestinal Contents / chemistry
- Horse Diseases / diet therapy
- Horse Diseases / etiology
- Horses
- Hydrogen-Ion Concentration
- Intestinal Diseases / etiology
- Intestinal Diseases / veterinary
- Lithiasis / etiology
- Lithiasis / veterinary
- Risk Factors
Citations
This article has been cited 6 times.- Albanese V, Munsterman A, Klohnen A. Prevalence of Gastric Ulceration in Horses with Enterolithiasis Compared with Horses with Simple Large Intestinal Obstruction.. Vet Sci 2022 Oct 25;9(11).
- Turek B, Witkowski M, Drewnowska O. Enterolithiasis in horses: analysis of 15 cases treated surgically in Saudi Arabia.. Iran J Vet Res 2019 Fall;20(4):270-276.
- Curtis L, Burford JH, England GCW, Freeman SL. Risk factors for acute abdominal pain (colic) in the adult horse: A scoping review of risk factors, and a systematic review of the effect of management-related changes.. PLoS One 2019;14(7):e0219307.
- Nakamae Y, Ishihara A, Itoh M, Yanagawa M, Sasaki N, Yamada K. Displacement of the large colon in a horse with enterolithiasis due to changed positions observed by computed tomography.. J Equine Sci 2018;29(1):9-13.
- Iwamuro M, Urata H, Hiraoka S, Ohmori M, Kondo Y, Kawahara Y, Okada H. A Calcium Enterolith in a Patient with Crohn's Disease and Its In Vitro Dissolubility in Citric Acid.. Case Rep Gastrointest Med 2017;2017:2951547.
- Oreff GL, Shiraki R, Kelmer G. Removal of sialoliths using the intraoral approach in 15 horses.. Can Vet J 2016 Jun;57(6):647-50.
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