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Current topics in microbiology and immunology2012; 359; 11-23; doi: 10.1007/82_2012_214

Ecological aspects of hendra virus.

Abstract: Hendra virus, a novel and fatally zoonotic member of the family Paramyxoviridae, was first described in Australia in 1994. Periodic spillover from its natural host (fruit bats) results in catastrophic disease in horses and occasionally the subsequent infection of humans. Prior to 2011, 14 equine incidents involving seven human cases (four fatal) were recorded. The year 2011 saw a dramatic departure from the sporadic incidents of the previous 16 years, with a cluster of 18 incidents in a single 3-month period. The fundamental difference in 2011 was the total number of incidents, the geographic clustering, and the expanded geographic range. The 2011 cluster more than doubled the total number of incidents previously reported, and poses the possibility of a new HeV infection paradigm. Epidemiologic evidence suggests that compelling additional host and/or environmental factors were at play.
Publication Date: 2012-04-06 PubMed ID: 22476530DOI: 10.1007/82_2012_214Google Scholar: Lookup
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Summary

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The research article presents a study on Hendra virus, a lethal zoonotic virus first discovered in Australia in 1994. It mainly identifies the potential changes in the patterns of HeV infection based on an increased number of recorded incidents in 2011 as compared to the previous years.

Hendra Virus

  • The study covers the Hendra virus (HeV), a deadly zoonotic virus belonging to the Paramyxoviridae family. It was first identified in 1994 in Australia.
  • HeV commonly affects fruit bats, its natural host, but sporadically spills over to horses, causing severe disease. Occasionally, humans get infected from the infected horses.

Historical Incident Data

  • Prior to 2011, there had been 14 equine incidents which led to seven human cases, out of which four were fatal.

The 2011 Cluster

  • In 2011, there was a significant increase in the occurrence of HeV incidents, with 18 incidents observed within three months. This dramatic surge was unusual compared to the sporadic incidents recorded in the preceding 16 years.
  • Notable differences during this year included the total number of incidents, geographic clustering, and the expansion of the geographic range.
  • This surge doubled the total number of HeV incidents previously reported, suggesting a possible new pattern of HeV infections.

Epidemiology and Other Factors

  • The researchers hypothesize that other host or environmental factors may have been involved, as suggested by the epidemiological evidence.
  • The study does not mention what these factors could be, implying that further research is needed to identify and understand these additional factors and their role in the spread of HeV.

Cite This Article

APA
Field H, Crameri G, Kung NY, Wang LF. (2012). Ecological aspects of hendra virus. Curr Top Microbiol Immunol, 359, 11-23. https://doi.org/10.1007/82_2012_214

Publication

ISSN: 0070-217X
NlmUniqueID: 0110513
Country: Germany
Language: English
Volume: 359
Pages: 11-23

Researcher Affiliations

Field, Hume
  • Biosecurity Queensland, Department of Employment, Economic Development and Innovation, Brisbane, QLD, Australia. hume.field@qld.gov.au
Crameri, Gary
    Kung, Nina Yu-Hsin
      Wang, Lin-Fa

        MeSH Terms

        • Animals
        • Australia / epidemiology
        • Chiroptera / virology
        • Disease Outbreaks
        • Ecosystem
        • Hendra Virus / isolation & purification
        • Hendra Virus / pathogenicity
        • Henipavirus Infections / epidemiology
        • Henipavirus Infections / veterinary
        • Henipavirus Infections / virology
        • Horse Diseases / epidemiology
        • Horse Diseases / virology
        • Horses / virology
        • Humans
        • Phylogeography
        • Zoonoses / epidemiology
        • Zoonoses / virology