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Animals : an open access journal from MDPI2024; 14(5); doi: 10.3390/ani14050727

Effect of Exercise Conditioning on Countering the Effects of Obesity and Insulin Resistance in Horses-A Review.

Abstract: Obesity is an important health concern in horses, along with humans and companion animals. Adipose tissue is an inflammatory organ that alters the insulin-signaling cascade, ultimately causing insulin dysregulation and impaired glucose metabolism. These disruptions can increase the risk of metabolic disease and laminitis in horses and may also impact energy metabolism during exercise. A single bout of exercise, along with chronic exercise conditioning, increases insulin sensitivity and glucose disposal via both contraction- and insulin-mediated glucose uptake pathways. Regular exercise also increases calorie expenditure, which can facilitate weight (as body fat) loss. This paper explores the metabolic pathways affected by adiposity, as well as discusses the impact of exercise on insulin metabolism in horses.
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Publication Date: 2024-02-26 PubMed ID: 38473112PubMed Central: PMC10931081DOI: 10.3390/ani14050727Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article explores the effects of exercise on combating obesity and insulin resistance in horses, by examining the role of adipose tissue and how physical activity can enhance insulin sensitivity and glucose metabolism.

Overview of adiposity and exercise

  • The main focus of the paper is on the impact of obesity and insulin resistance in horses, common health issues that also affect humans and other companion animals.
  • Adiposity, the state of being obese or having excess body fat, is studied in relation to metabolic disruptions it can cause in horses.
  • The researchers examine how adipose tissue, known as an inflammatory organ, can alter the insulin-signaling cascade, leading to insulin dysregulation and impaired glucose metabolism. These changes can increase horses’ risk for metabolic diseases and laminitis.

Effects of Exercise on Horses

  • Among the potential solutions examined here, exercise emerges as a significant factor in combating these issues. Particularly, the impact of a single bout and chronic exercise conditioning on insulin sensitivity and glucose disposal is discussed.
  • Physical activity is suggested to enhance both contraction- and insulin-mediated glucose uptake pathways, resulting in improved energy metabolism during exercise and overall horse health.
  • Exercise also boosts calorie expenditure, which can contribute to weight loss in terms of body fat reduction.

The Connection between Adiposity, Exercise and Insulin Metabolism

  • This paper meticulously explores the complex metabolic pathways affected by adiposity, providing a comprehensive look at the potential harms of obesity in horses.
  • The researchers also delve extensively into the role of exercise in insulin metabolism, illustrating how physical conditioning can help manage and even alleviate obesity and related disorders.

Conclusion

  • Overall, this research offers valuable insights for equine health practitioners, providing evidence-backed strategies for tackling obesity and insulin resistance in horses through exercise.
  • While the paper focuses on horses, it may also bear implications for understanding obesity and insulin resistance in a broader range of animals, including humans.

Cite This Article

APA
Pratt-Phillips S. (2024). Effect of Exercise Conditioning on Countering the Effects of Obesity and Insulin Resistance in Horses-A Review. Animals (Basel), 14(5). https://doi.org/10.3390/ani14050727

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 14
Issue: 5

Researcher Affiliations

Pratt-Phillips, Shannon
  • Department of Animal Science, North Carolina State University, Raleigh, NC 27607, USA.

Conflict of Interest Statement

The author declares no conflicts of interest.

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