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Effects of preanesthetic medication, anesthesia, and position of recumbency on central venous pressure in horses.

Abstract: Central venous pressure (cvp) was recorded in horses before and after tranquilization and during halothane-maintained anesthesia in lateral or dorsal recumbency. The cvp was significantly decreased after administration of acetylpromazine, when compared with base line measurements and measurements taken after xylazine administration. After induction of anesthesia, cvp increased with time for 75 minutes, and values in lateral recumbency were significantly higher than those in dorsal recumbency.
Publication Date: 1977-01-15 PubMed ID: 833047
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  • Journal Article

Summary

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This study explores how central venous pressure (CVP) in horses is influenced by preanesthetic medication, anesthesia, and their physical position during anesthesia. The research discovered that certain tranquilizers significantly lower CVP, while the application of specific anesthesia and the horse’s positioning can measurably impact CVP levels.

Understanding Central Venous Pressure (CVP)

  • Central venous pressure refers to the pressure of blood in the thoracic vena cava, near the right atrium of the heart. CVP indicates the amount of blood returning to the heart and the ability of the heart to pump the blood back into the arterial system, therefore it’s a crucial factor to evaluate in the context of veterinary anesthesia.

Preanesthetic Medication and its Influence on CVP

  • This research found that the use of acetylpromazine, a tranquilizer, significantly reduced central venous pressure in horses. The same observation was not made when xylazine was administered as a tranquilizer.
  • This implies that the choice of preanesthetic medication can have a direct effect on the horse’s cardiovascular dynamics and should be considered carefully.

Anesthesia’s Impact on CVP

  • After the initiation of anesthesia, it was noted that central venous pressure increased over time, peaking at approximately 75 minutes into the procedure.
  • Understanding this trend is important for effective management of blood pressure during anesthesia, as the increase in CVP might dictate adjustments in anesthesia protocol or changes in therapeutic strategies.

Effect of Recumbency Position on CVP

  • The research also found that the position of the horse during anesthesia affected CVP. Specifically, the central venous pressure was significantly higher when the horse was in a lateral recumbency (lying on its side) as opposed to dorsal recumbency (lying on its back).
  • This suggests that the physical position of the horse during the procedure can significantly influence cardiovascular dynamics and should be considered in preoperative planning to ensure the horse’s safety and wellbeing throughout the operation.

Cite This Article

APA
Klein L, Sherman J. (1977). Effects of preanesthetic medication, anesthesia, and position of recumbency on central venous pressure in horses. J Am Vet Med Assoc, 170(2), 216-219.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 170
Issue: 2
Pages: 216-219

Researcher Affiliations

Klein, L
    Sherman, J

      MeSH Terms

      • Acepromazine / pharmacology
      • Anesthesia / veterinary
      • Animals
      • Central Venous Pressure / drug effects
      • Horses / physiology
      • Posture
      • Preanesthetic Medication / veterinary
      • Xylazine / pharmacology

      Citations

      This article has been cited 3 times.
      1. Singh V, Amarpal, Kinjavdekar P, Aithal HP, Pratap K. Medetomidine with ketamine and bupivacaine for epidural analgesia in buffaloes.. Vet Res Commun 2005 Jan;29(1):1-18.
      2. Kerr CL, McDonell WN, Young SS. Cardiopulmonary effects of romifidine/ketamine or xylazine/ketamine when used for short duration anesthesia in the horse.. Can J Vet Res 2004 Oct;68(4):274-82.
        pubmed: 15581222
      3. Gasthuys F, De Moor A, Parmentier D. Haemodynamic changes during sedation in ponies.. Vet Res Commun 1990;14(4):309-27.
        doi: 10.1007/BF00350713pubmed: 2392824google scholar: lookup