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Epidemiology of African horsesickness: duration of viraemia in zebra (Equus burchelli).

Abstract: The viraemic period of African horsesickness is significantly longer in experimentally infected zebra than in horses. The virus could be isolated 40 d post-infection from blood and 48 d post-infection from spleen. The introduction of zebra into African horsesickness-free countries should therefore be considered carefully, and preferably be restricted to serologically negative zebra.
Publication Date: 1994-12-01 PubMed ID: 7501371
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigated the African horsesickness virus in zebras, finding it stayed in their system longer than it did in horses. This provided important insights for potential introductions of zebras into horsesickness-free regions.

Study Focus and Methodology

  • The research focused on understanding the duration of the African horsesickness virus in zebras as compared to horses. Particularly, the research wanted to establish how long the virus could survive in the blood and spleen of the infected zebras.
  • The researchers used an experimental approach to infect the zebras with the African horsesickness virus. They then monitored the zebras over a period, regularly taking samples of the blood and spleen tissue to test for the presence of the virus.

Research Findings

  • The findings suggested that the African horsesickness virus persisted for a significantly longer duration in zebras than in horses. The virus was still present in the zebras’ blood even 40 days post infection.
  • Further, the virus was isolable from the zebras’ spleen 48 days after infection, implying that the spleen could act as a repository for the virus over a prolonged period.

Implication of the Study

  • The results imply that zebras could be a potential long-term carrier of the African horsesickness virus. Since they can harbor the virus for longer durations, they could potentially aid in the spread of the virus into horsesickness-free regions.
  • The study thus advises careful consideration of introducing zebras into regions free of African horsesickness. In particular, the research suggests that the introduction of zebras should be restricted to those that are serologically confirmed to be negative for the virus.

Cite This Article

APA
Barnard BJ, Bengis R, Keet D, Dekker EH. (1994). Epidemiology of African horsesickness: duration of viraemia in zebra (Equus burchelli). Onderstepoort J Vet Res, 61(4), 391-393.

Publication

ISSN: 0030-2465
NlmUniqueID: 0401107
Country: South Africa
Language: English
Volume: 61
Issue: 4
Pages: 391-393

Researcher Affiliations

Barnard, B J
  • Onderstepoort Veterinary Institute, South Africa.
Bengis, R
    Keet, D
      Dekker, E H

        MeSH Terms

        • African Horse Sickness / epidemiology
        • African Horse Sickness / virology
        • African Horse Sickness Virus / isolation & purification
        • Animals
        • Horse Diseases / epidemiology
        • Horses
        • South Africa / epidemiology

        Citations

        This article has been cited 7 times.
        1. Gao H, Wang L, Ma J, Gao X, Xiao J, Wang H. Modeling the current distribution suitability and future dynamics of Culicoides imicola under climate change scenarios. PeerJ 2021;9:e12308.
          doi: 10.7717/peerj.12308pubmed: 34760364google scholar: lookup
        2. Grewar JD, Kotze JL, Parker BJ, van Helden LS, Weyer CT. An entry risk assessment of African horse sickness virus into the controlled area of South Africa through the legal movement of equids. PLoS One 2021;16(5):e0252117.
          doi: 10.1371/journal.pone.0252117pubmed: 34038466google scholar: lookup
        3. Porphyre T, Grewar JD. Assessing the potential of plains zebra to maintain African horse sickness in the Western Cape Province, South Africa. PLoS One 2019;14(10):e0222366.
          doi: 10.1371/journal.pone.0222366pubmed: 31671099google scholar: lookup
        4. Thompson GM, Jess S, Murchie AK. A review of African horse sickness and its implications for Ireland. Ir Vet J 2012 Jul 5;65(1):9.
          doi: 10.1186/2046-0481-65-9pubmed: 22553991google scholar: lookup
        5. Wilson A, Mellor PS, Szmaragd C, Mertens PP. Adaptive strategies of African horse sickness virus to facilitate vector transmission. Vet Res 2009 Mar-Apr;40(2):16.
          doi: 10.1051/vetres:2008054pubmed: 19094921google scholar: lookup
        6. Kuno G, Chang GJ. Biological transmission of arboviruses: reexamination of and new insights into components, mechanisms, and unique traits as well as their evolutionary trends. Clin Microbiol Rev 2005 Oct;18(4):608-37.
          doi: 10.1128/CMR.18.4.608-637.2005pubmed: 16223950google scholar: lookup
        7. Pitchers KG, Boakye OD, Campeotto I, Daly JM. The Potential of Plant-Produced Virus-like Particle Vaccines for African Horse Sickness and Other Equine Orbiviruses. Pathogens 2024 May 28;13(6).
          doi: 10.3390/pathogens13060458pubmed: 38921755google scholar: lookup