Epidemiology of equine protozoal myeloencephalitis in North America based on histologically confirmed cases. A report.
Abstract: Following a workshop on equine protozoal myeloencephalitis (EPM) convened at the Veterinary Medical Forum of the American College of Veterinary Internal Medicine in 1988, this survey of EPM in North America was developed. It is based upon 364 histologically confirmed case records from California, Florida, Illinois, Kentucky, New York, Ohio, Oklahoma, Ontario, Pennsylvania, and Texas up to 1988. The highest rate of infection was found in young Thoroughbred, Standardbred, and quarter horses. Differences in geographic location, sex, and month (season) of infection were not discernible. This report, the first comprehensive survey of EPM in North America, is intended to serve as a basis for evaluating future changes in prevalence and spread of EPM.
Publication Date: 1990-03-01 PubMed ID: 2342022DOI: 10.1111/j.1939-1676.1990.tb03103.xGoogle Scholar: Lookup
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- Journal Article
Summary
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This study is a survey on equine protozoal myeloencephalitis (EPM) in North America, based on 364 histologically confirmed cases until 1988. It aims to underscore the prevalent rate of this disease in young Thoroughbred, Standardbred, and quarter horses and lays a foundation for future studies on this topic.
Research Background
- The research is based on a workshop on equine protozoal myeloencephalitis (EPM) that was held at the Veterinary Medical Forum of the American College of Veterinary Internal Medicine in 1988. EPM is a severe neurological disease that can affect horses, caused by a protozoan parasite.
- This study is the first comprehensive survey of EPM in North America aiming to establish understanding and provide a foundation for future studies.
Methodology
- The study used 364 histologically confirmed case records from several places including California, Florida, Illinois, Kentucky, New York, Ohio, Oklahoma, Ontario, Pennsylvania, and Texas up to 1988.
- The research did not identify discernible differences based on geographic location, sex, and season of infection, signifying that these factors could not conclusively determine the prevalence or susceptibility of horses to EPM.
Key Findings
- Based on the recorded cases, the highest rate of infection was found in young Thoroughbred, Standardbred, and quarter horses, pointing to a higher prevalence of EPM in these horses.
- There were no substantial differences found in relation to the geographic location, sex, and month (season) of infection, which could be significant in guiding future research on EPM.
Research Implications
- This research forms the basis for understanding the prevalence and spread of EPM in North America and serves as a foundation for evaluating future changes in these aspects.
- The findings can be critical in directing future research where focus might be placed on studying why certain breeds of horses are more susceptible to EPM and devising strategies to prevent or treat the disease among those breeds.
Cite This Article
APA
Fayer R, Mayhew IG, Baird JD, Dill SG, Foreman JH, Fox JC, Higgins RJ, Reed SM, Ruoff WW, Sweeney RW.
(1990).
Epidemiology of equine protozoal myeloencephalitis in North America based on histologically confirmed cases. A report.
J Vet Intern Med, 4(2), 54-57.
https://doi.org/10.1111/j.1939-1676.1990.tb03103.x Publication
Researcher Affiliations
- Zoonotic Diseases Laboratory, U.S. Department of Agriculture, Beltsville, MD 20705.
MeSH Terms
- Animals
- Encephalomyelitis / epidemiology
- Encephalomyelitis / veterinary
- Female
- Horse Diseases / epidemiology
- Horses
- Male
- Ontario / epidemiology
- Prevalence
- Protozoan Infections / epidemiology
- Protozoan Infections, Animal
- Retrospective Studies
- United States / epidemiology
Citations
This article has been cited 8 times.- Bedenice D, Johnson AL. Neurologic conditions in the sport horse. Anim Front 2022 Jun;12(3):37-44.
- Aleman M, Berryhill E, Woolard K, Easton-Jones CA, Kozikowski-Nicholas T, Dyson S, Kilcoyne I. Sidewinder gait in horses. J Vet Intern Med 2020 Sep;34(5):2122-2131.
- Johnstone LK, Engiles JB, Aceto H, Buechner-Maxwell V, Divers T, Gardner R, Levine R, Scherrer N, Tewari D, Tomlinson J, Johnson AL. Retrospective Evaluation of Horses Diagnosed with Neuroborreliosis on Postmortem Examination: 16 Cases (2004-2015). J Vet Intern Med 2016 Jul;30(4):1305-12.
- Reed SM, Furr M, Howe DK, Johnson AL, MacKay RJ, Morrow JK, Pusterla N, Witonsky S. Equine Protozoal Myeloencephalitis: An Updated Consensus Statement with a Focus on Parasite Biology, Diagnosis, Treatment, and Prevention. J Vet Intern Med 2016 Mar-Apr;30(2):491-502.
- Rejmanek D, Miller MA, Grigg ME, Crosbie PR, Conrad PA. Molecular characterization of Sarcocystis neurona strains from opossums (Didelphis virginiana) and intermediate hosts from Central California. Vet Parasitol 2010 May 28;170(1-2):20-9.
- Wobeser BK, Godson DL, Rejmanek D, Dowling P. Equine protozoal myeloencephalitis caused by Neospora hughesi in an adult horse in Saskatchewan. Can Vet J 2009 Aug;50(8):851-3.
- Liang FT, Granstrom DE, Zhao XM, Timoney JF. Evidence that surface proteins Sn14 and Sn16 of Sarcocystis neurona merozoites are involved in infection and immunity. Infect Immun 1998 May;66(5):1834-8.
- Valderrama-Martinez C, Packham A, Zheng S, Smith W, Plancarte M, Aleman M. Effect of refrigeration, room temperature, and processing time on serum immunofluorescent antibody titers for Sarcocystis neurona. J Vet Intern Med 2025 Jan-Feb;39(1):e17282.
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