Equine cardiac disease. Clinical pharmacology and therapeutics.
Abstract: Cardiac disease is often life-threatening and challenging to treat. Prolonged therapy is indicated in many cases, which can lead to problems with treatment costs, owner compliance, and potential drug toxicity. Many therapies are empirical or based on data from other species because of a lack of well-designed prospective clinical trials in horses. This article reviews the clinical pharmacology and therapeutics of heart failure, cardiac arrhythmias, myocardial disease, endocarditis, and pericardial disease.
Publication Date: 1999-12-10 PubMed ID: 10589465DOI: 10.1016/s0749-0739(17)30130-xGoogle Scholar: Lookup
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- Journal Article
- Review
- Cardiac Arrhythmias
- Cardiovascular Health
- Clinical Examination
- Clinical Pathology
- Clinical Signs
- Clinical Study
- Clinical Symptoms
- Disease Management
- Disease Treatment
- Equine Diseases
- Equine Health
- Heart
- Horses
- Pharmacodynamics
- Pharmacokinetics
- Pharmacology
- Veterinary Care
- Veterinary Medicine
- Veterinary Practice
- Veterinary Research
Summary
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This research discusses the treatment complications of cardiac disease in horses. The authors underline the scarcity of relevant clinical trials and review the prevalent treatments for several heart conditions in horses.
The Challenge of Treating Cardiac Disease in Horses
- The study sheds light on the difficulties surrounding the treatment of cardiac disease in horses, a condition often associated with significant risk to life. Among these difficulties are high treatment costs, compliance with a prolonged therapy regime, and potential drug toxicity. These issues together can complicate the treatment process and result in suboptimal outcomes.
Lack of Well-Designed Prospective Clinical Trials
- The research points out there is a serious lack of comprehensive, well-structured prospective clinical trials focused on equine cardiac disease. This gap in research leaves practitioners reliant on experience-based or empirical therapies and data extrapolated from studies on other species. It suggests the pressing need for more research specifically targeted toward equine cardiac diseases.
Review of Current Therapies
- The paper broadly discusses the clinical pharmacology and therapeutics associated with managing different types of heart conditions in horses, including heart failure, cardiac arrhythmias, myocardial disease, endocarditis, and pericardial disease. By doing so, it provides valuable insights into current conventional treatment modalities and their efficacy in managing various cardiac conditions in horses.
Implications and Recommendations
- In conclusion, the paper brings to the fore the need for more targeted research in the field of equine cardiac diseases treatment. It further recommends that given the limitations and challenges surrounding current treatment regimes, the focus should be on developing better and more effective therapeutic solutions specifically designed for horses.
Cite This Article
APA
Mogg TD.
(1999).
Equine cardiac disease. Clinical pharmacology and therapeutics.
Vet Clin North Am Equine Pract, 15(3), 523-vii.
https://doi.org/10.1016/s0749-0739(17)30130-x Publication
Researcher Affiliations
- Institute of Veterinary, Animal, and Biomedical Sciences, Massey University, Palmerston North, New Zealand.
MeSH Terms
- Animals
- Anti-Arrhythmia Agents / therapeutic use
- Anti-Bacterial Agents / therapeutic use
- Cardiotonic Agents / therapeutic use
- Diuretics / therapeutic use
- Heart Diseases / drug therapy
- Heart Diseases / veterinary
- Horse Diseases / drug therapy
- Horses
- Vasodilator Agents / therapeutic use
References
This article includes 30 references
Citations
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