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The Veterinary clinics of North America. Equine practice2006; 22(3); 857-866; doi: 10.1016/j.cveq.2006.07.004

Equine cloning.

Abstract: Equine cloning is now in use as a clinical technique. It is available commercially, and its efficiency seems to be increasing. The foals produced by cloning may differ in some phenotypic and behavioral traits from the original animal but should produce offspring that reflect those that the original donor animal would have produced. This is especially true in the case of male animals, where the mitochondrial DNA is not passed to the progeny. Results of pregnancies due in 2006 should add significantly to our understanding of the factors affecting production of viable cloned foals and of the similarities and differences among cloned foals and between these foals and the donor animals.
Publication Date: 2006-11-30 PubMed ID: 17129808DOI: 10.1016/j.cveq.2006.07.004Google Scholar: Lookup
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  • Journal Article
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  • Non-U.S. Gov't
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Summary

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The research looks into the clinical technique of equine cloning, its commercial availability, efficiency, and the attributes of the offspring produced. The observations are aimed at enhancing understanding of the factors affecting production of clone foals and their similarities or differences to the donor animals.

Commercial Use and Efficiency of Equine Cloning

  • The paper highlights that equine cloning is not just a theoretical possibility anymore. The technology is in actual clinical use, paving the way for its commercial availability across the world. This signifies the strides made in biotechnological procedures in the field of animal cloning.
  • The study finds an increasing efficiency in the cloning process, that is, the percentage of successful cloning experiments are on the rise, reducing wastage and increasing predictability.

Phenotypic and Behavioral Traits of Clone Foals

  • The researchers highlight an interesting observation: clone foals, while identical to the donor genetically, exhibit some differences in their phenotypic and behavioral traits. This suggests that genetics aren’t the only determinant of these traits; environmental influence post-birth might play a significant role too.

Foals’ Inheritance of Traits from the Donor

  • The paper explains how the clone foals should theoretically inherit the traits of the donor animals. This is particularly so in male animals, given that mitochondrial DNA does not get passed onto the progeny.
  • However, the authors suggest the need for further results, particularly from pregnancies due in 2006. These impending results hold the potential to substantiate the observations made so far regarding trait inheritance.

Current and Future Understanding of Equine Cloning

  • With continued research and studies, the authors hope to shed light on the factors that impact the production of viable clone foals, besides unravelling the genetic mysteries of similarities and differences among clone foals, and between them and donor animals.

Cite This Article

APA
Hinrichs K. (2006). Equine cloning. Vet Clin North Am Equine Pract, 22(3), 857-866. https://doi.org/10.1016/j.cveq.2006.07.004

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 22
Issue: 3
Pages: 857-866

Researcher Affiliations

Hinrichs, Katrin
  • Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4466, USA. khinrichs@cvm.tamu.edu

MeSH Terms

  • Animals
  • Cloning, Organism / methods
  • Cloning, Organism / veterinary
  • Embryo Transfer / veterinary
  • Female
  • Horses / physiology
  • Pregnancy
  • Pregnancy Outcome / veterinary

Citations

This article has been cited 4 times.
  1. Campbell MLH. Is cloning horses ethical?. Equine Vet Educ 2018 May;30(5):268-273.
    doi: 10.1111/eve.12566pubmed: 29937631google scholar: lookup
  2. Campbell ML, Sandøe P. Welfare in horse breeding. Vet Rec 2015 Apr 25;176(17):436-40.
    doi: 10.1136/vr.102814pubmed: 25908746google scholar: lookup
  3. Cortez JV, Hardwicke K, Méndez-Calderón CE, Grupen CG. Effect of Pre-IVM Duration with cAMP Modulators on the Production of Cloned Equine Embryos and Foals. Animals (Basel) 2025 Jul 3;15(13).
    doi: 10.3390/ani15131961pubmed: 40646860google scholar: lookup
  4. Nesiyama TNG, Sangalli JR, De Bem THC, Recchia K, Martins SMMK, de Andrade AFC, Ferst JG, Almeida GHDR, Marques MG, Dória RGS, Carregaro AB, Feliciano MAR, Miglino MA, Bressan FF, Perecin F, da Silveira JC, Smith LC, Bordignon V, Meirelles FV. Swine clones: potential application for animal production and animal models. Anim Reprod 2025;22(1):e20240037.
    doi: 10.1590/1984-3143-AR2024-0037pubmed: 39867300google scholar: lookup