Equine Cushing’s disease.
Abstract: Equine Cushing's disease (ECD) is a chronic progressive disease of the intermediate pituitary gland of older horses. Horses with Cushing's disease often have other health problems, such as laminitis, chronic infections, pseudolactation, and other issues. Diagnosis of ECD is usually based on clinical signs and endocrine tests. Medical management of affected horses is usually a long-term or lifelong commitment. The goal of this article is to review the pathophysiology of ECD, outline diagnostic tests, and present treatment options.
Publication Date: 2003-01-09 PubMed ID: 12516933DOI: 10.1016/s0749-0739(02)00038-xGoogle Scholar: Lookup
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Summary
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The research article is about a chronic progressive disease in older horses, called Equine Cushing’s disease (ECD). The researchers discussed the pathophysiology of ECD, diagnostic tests, and treatment options.
Understanding Equine Cushing’s Disease (ECD)
- The article begins by describing ECD as a chronic condition that targets the intermediate lobes of the pituitary gland in elderly horses. This ailment, which steadily advances over time, often leads to several other health complications such as laminitis, chronic infections, pseudolactation, among other issues. Essentially, these secondary conditions are potentially hazardous and require appropriate medical interventions.
Diagnosis of Equine Cushing’s Disease
- The diagnosis of ECD is commonly based on the clinical signs exhibited by the horse, coupled with various endocrine tests designed to confirm the presence of the disease. The authors highlight that this combination of symptom recognition and medical testing is crucial to ensure a correct and prompt diagnosis of ECD. However, they do not detail specific endocrine tests used or potential biomarkers for the disease within the abstract.
Managing and Treating Equine Cushing’s Disease
- A significant portion of the article is drawn to the comprehensive management of ECD. They echo that treating horses affected by ECD is usually a long-term or lifelong commitment, emphasizing the resilient nature of this disease. The objective of the management and treatment strategy is predicated on controlling the symptoms, slowing the progression of the disease, and improving the overall quality of life for the affected horses.
Pathophysiology, Diagnostic Tests, and Treatment Options of ECD
- The main goal of the article is to offer a comprehensive review of ECD. The authors extensively discuss the pathophysiology of the disease, thereby giving their audience a deeper understanding of how it affects the pituitary gland and subsequent physiological processes. Furthermore, they outline various diagnostic tests that assist in identifying the disease.
- Also, they present treatment options that are currently available to manage ECD. However, an in-depth analysis of these treatment options is not provided within the article’s abstract. Therefore, to gain a complete understanding of these options, one would need to refer to the full text of the research article.
Cite This Article
APA
McCue PM.
(2003).
Equine Cushing’s disease.
Vet Clin North Am Equine Pract, 18(3), 533-viii.
https://doi.org/10.1016/s0749-0739(02)00038-x Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine and Biological Sciences, Colorado State University, Fort Collins, CO 80523, USA. pmccue@colostate.edu
MeSH Terms
- Animals
- Cushing Syndrome / diagnosis
- Cushing Syndrome / etiology
- Cushing Syndrome / therapy
- Cushing Syndrome / veterinary
- Horse Diseases / diagnosis
- Horse Diseases / etiology
- Horse Diseases / physiopathology
- Horse Diseases / therapy
- Horses
- Hydrocortisone / blood
Citations
This article has been cited 4 times.- Sahm A, Platzer M, Koch P, Henning Y, Bens M, Groth M, Burda H, Begall S, Ting S, Goetz M, Van Daele P, Staniszewska M, Klose JM, Costa PF, Hoffmann S, Szafranski K, Dammann P. Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis. Elife 2021 Mar 16;10.
- Hughes K. Development and Pathology of the Equine Mammary Gland. J Mammary Gland Biol Neoplasia 2021 Jun;26(2):121-134.
- To T. Inappropriate lactation in a 15-year-old thoroughbred mare. Can Vet J 2019 Apr;60(4):430-433.
- Williams ZJ, Pezzanite LM, Hendrickson DA. Review of skin grafting in equine wounds: indications and techniques. Equine Vet Educ 2024 Sep;36(9):484-493.
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