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Home / Equine Research Bank / Vet Rec / Equine glanders in Turkey.
The Veterinary record1999; 144(10); 255-258; doi: 10.1136/vr.144.10.255

Equine glanders in Turkey.

Abstract: In the course of an epidemiological study of glanders on a number of Turkish islands in the Sea of Marmara, 1128 horses were examined by using the intracutaneous mallein test. Thirty-five (3-1 per cent) developed an increase in rectal temperature and a swelling at the point of injection. Ten of these horses were killed and glanders was confirmed in five cases by the presence of lesions and by the immunohistological demonstration of the causative agent, Burkholderia mallei. Clinical and pathological findings indicated that in all cases the infection was restricted to the mucous membrane of the nasal cavity with its parasinus, the nostrils and the upper lips. It was confirmed that equine glanders is endemic in Turkey.
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Publication Date: 1999-04-21 PubMed ID: 10209817DOI: 10.1136/vr.144.10.255Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research study was focused on investigating the occurrence of the disease glanders in horses living on several Turkish islands in the Sea of Marmara. The findings suggest that the disease, caused by Burkholderia mallei, is endemic in the area.

Research Method

  • The researchers took a total of 1128 horses and examined them using the intracutaneous mallein test, a specific and sensitive diagnostic procedure for detecting glanders in horses. The benefit of this test is that it can detect the disease even before clinical signs are apparent, enabling proactive treatment and control measures.
  • This test specifically involves injecting mallein – a protein derived from the bacteria that causes glanders – into the skin of the horse and examining the reaction. An increase in rectal temperature and a visible swelling at the point of injection typically indicates a positive reaction, suggesting the horse is infected.

Findings and Interpretation

  • Out of the total horses tested, about 3.1%, or 35 horses showed response to the mallein test, implying they might be infected with glanders.
  • To confirm this, ten of these suspected infected horses were euthanized, and on further investigation, glanders was confirmed in five cases.
  • The confirmatory procedure involved looking for the presence of lesions caused by the bacteria. Furthermore, an immunohistological test (a test that combines immunological and histological (tissue-based) techniques) was used to visually identify the presence of Burkholderia mallei, the bacteria responsible for causing glanders in these samples.
  • The findings from the investigation of the killed horses showed that the infection was limited to the mucous membrane of the nasal cavity, its parasinus, the nostrils, and the upper lips in all the cases, which is typical of glanders infection in horses.

Conclusion

  • The results from this study indicate that glanders remains a significant issue in the horse population on the Turkish islands in the Sea of Marmara.
  • The researchers have thereby confirmed that glanders disease is endemic in Turkey, meaning that it is commonly found among horses in this region.

Cite This Article

APA
Arun S, Neubauer H, Gürel A, Ayyildiz G, Kusçu B, Yesildere T, Meyer H, Hermanns W. (1999). Equine glanders in Turkey. Vet Rec, 144(10), 255-258. https://doi.org/10.1136/vr.144.10.255

Publication

The Veterinary record
ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 144
Issue: 10
Pages: 255-258

Researcher Affiliations

Arun, S
  • Institute for Animal Pathology, University of Istanbul, Turkey.
Neubauer, H
    Gürel, A
      Ayyildiz, G
        Kusçu, B
          Yesildere, T
            Meyer, H
              Hermanns, W

                MeSH Terms

                • Animals
                • Burkholderia / isolation & purification
                • Burkholderia / pathogenicity
                • Disease Transmission, Infectious / veterinary
                • Female
                • Glanders / epidemiology
                • Glanders / microbiology
                • Horses
                • Male
                • Nasal Cavity / microbiology
                • Nasal Cavity / pathology
                • Turkey / epidemiology

                Citations

                This article has been cited 25 times.
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