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The Veterinary clinics of North America. Equine practice2023; 39(1); 133-145; doi: 10.1016/j.cveq.2022.11.011

Equine Granulocytic Anaplasmosis.

Abstract: Equine granulocytic anaplasmosis is a clinically significant and common disease of equids that has a broader prevalence than was once thought. The most common clinical signs include high fever and edema, with mild to mderate thrombocytopenia and lymphopenia typically noted on complete blood count. Subclinical cases are reported and many are self-limiting. Rare clinical presentations include neurologic disease, vasculitis, dysphagia, rhabdomyolysis, or bicavitary effusion. Most cases resolve rapidly with appropriate antimicrobial intervention.
Publication Date: 2023-02-01 PubMed ID: 36737288DOI: 10.1016/j.cveq.2022.11.011Google Scholar: Lookup
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Summary

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The research article focuses on equine granulocytic anaplasmosis which is a common ailment in horses. This disease is more prevalent than previously believed and can induce symptoms like fever and edema. However, normal treatment with antimicrobials leads to quick recovery in most cases.

Overview of the Disease

  • The research discusses equine granulocytic anaplasmosis, a well-known yet widespread disease in equids, or animals from the equidae family including horses, donkeys, and zebras.
  • Contrary to earlier beliefs, the disease is found quite common and more widespread.

Clinical Manifestations

  • It primarily manifests as high fever and edema, a condition marked by an excess of watery fluid collecting in the cavities or tissues of the body, in the affected animals.
  • The complete blood count in such cases typically shows signs of mild to moderate thrombocytopenia, which is a lower than normal number of platelets (thrombocytes) in the blood, and lymphopenia or the condition of low levels of lymphocytes, a type of white blood cells, in the blood.
  • It also details unusual clinical presentations like neurologic disease, vasculitis (inflammation of the blood vessels), dysphagia (difficulties in swallowing), rhabdomyolysis (breakdown of damaged skeletal muscle), or bicavitary effusion (fluid accumulation in two different cavities).

Subclinical Cases and Treatment

  • Silent or subclinical cases of the disease, where horses are infected but do not show visible symptoms or signs, are also mentioned in the research.
  • Notably, many such cases are self-limiting, in that, they improve on their own without any external treatment or intervention.
  • The paper concludes by stating that with appropriate antimicrobial treatment, most active cases of equine granulocytic anaplasmosis resolve rapidly, indicating a positive outcome and recovery with timely medical intervention.

Cite This Article

APA
Oliver A, Conrado FO, Nolen-Walston R. (2023). Equine Granulocytic Anaplasmosis. Vet Clin North Am Equine Pract, 39(1), 133-145. https://doi.org/10.1016/j.cveq.2022.11.011

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 39
Issue: 1
Pages: 133-145

Researcher Affiliations

Oliver, Andrea
  • Department of Clinical Studies, University of Pennsylvania, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA.
Conrado, Francisco O
  • Department of Comparative Pathobiology, Tufts University, Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA.
Nolen-Walston, Rose
  • Department of Clinical Studies, University of Pennsylvania, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA. Electronic address: rnolenw@upenn.edu.

MeSH Terms

  • Anaplasmosis / diagnosis
  • Anaplasmosis / drug therapy
  • Anaplasmosis / epidemiology
  • Anaplasmosis / pathology
  • Anti-Bacterial Agents / therapeutic use
  • Horse Diseases / diagnosis
  • Horse Diseases / drug therapy
  • Horse Diseases / epidemiology
  • Horse Diseases / pathology
  • Horses
  • Seroepidemiologic Studies
  • Tetracycline / therapeutic use
  • Animals