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The Veterinary clinics of North America. Equine practice2009; 25(2); 381-399; doi: 10.1016/j.cveq.2009.04.006

Equine grass sickness: epidemiology, diagnosis, and global distribution.

Abstract: Equine grass sickness (EGS) is recognized as a debilitating and predominantly fatal neurodegenerative disease affecting grazing equids. The gastrointestinal tract is the most severely affected body system, resulting in the main clinical signs of colic (acute grass sickness), weight loss, or dysphagia (chronic grass sickness). EGS predominantly occurs within Great Britain, although it is also recognized in regions of mainland Europe, and mainly affects young horses with access to pasture in the springtime. There is strong evidence of an association between EGS and the type C toxins produced by the bacterium Clostridium botulinum. This article covers the clinical aspects, epidemiology, and global distribution of EGS, along with comparisons with botulism and developments in disease prevention.
Publication Date: 2009-07-08 PubMed ID: 19580947DOI: 10.1016/j.cveq.2009.04.006Google Scholar: Lookup
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Summary

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The research article discusses Equine grass sickness (EGS), a fatal neurodegenerative disease in grazing horses linked to toxins produced by the bacterium Clostridium botulinum, its clinical aspects, epidemiology, and distribution, as well as disease prevention methods.

Epidemiology and Distribution of EGS

  • This study discusses EGS, a predominantly fatal disease in grazing horses, which affects their gastrointestinal tract. The impact on the digestive system results in colic (also known as acute grass sickness), weight loss, or dysphagia (chronic grass sickness).
  • Although EGS is most common in Great Britain, it’s also found in some regions of mainland Europe. Typically, the disease primarily impacts young horses with pasture access, especially during the spring season.
  • The researchers detail the global distribution of EGS, emphasizing its predominant occurrence within Great Britain and existence in specific regions in mainland Europe.

Association with Clostridium Botulinum

  • The research provides substantial evidence that links EGS with type C toxins produced by the bacterium Clostridium botulinum.

Clinical Aspects of EGS

  • The article explains the primary clinical signs of the disease, including colic, weight loss, and dysphagia. Evidence shows that these symptoms are due to the severe impact the disease has on the horses’ gastrointestinal systems.

Comparisons with Botulism

  • The researchers draw comparisons between EGS and botulism, another disease caused by toxins produced by the bacterium Clostridium botulinum.

Disease Prevention

  • Finally, the article considers advancements in the prevention of EGS, although it does not specify what these preventive methods entail.

Cite This Article

APA
Wylie CE, Proudman CJ. (2009). Equine grass sickness: epidemiology, diagnosis, and global distribution. Vet Clin North Am Equine Pract, 25(2), 381-399. https://doi.org/10.1016/j.cveq.2009.04.006

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 25
Issue: 2
Pages: 381-399

Researcher Affiliations

Wylie, Claire E
  • Epidemiology and Disease Surveillance, Animal Health Trust, Centre for Preventive Medicine, Lanwades Park, Kentford, Newmarket, Suffolk, England. claire.wylie@aht.org.uk
Proudman, Chris J

    MeSH Terms

    • Animals
    • Gastrointestinal Diseases / diagnosis
    • Gastrointestinal Diseases / epidemiology
    • Gastrointestinal Diseases / pathology
    • Gastrointestinal Diseases / veterinary
    • Global Health
    • Horse Diseases / diagnosis
    • Horse Diseases / epidemiology
    • Horse Diseases / pathology
    • Horses

    Citations

    This article has been cited 4 times.
    1. Laus F, Corsalini J, Mandara MT, Bazzano M, Bertoletti A, Gialletti R. Equine grass sickness in italy: a case series study.. BMC Vet Res 2021 Aug 6;17(1):264.
      doi: 10.1186/s12917-021-02966-ypubmed: 34362361google scholar: lookup
    2. Randleff-Rasmussen PK, Leblond A, Cappelle J, Bontemps J, Belluco S, Popoff MR, Marcillaud-Pitel C, Tapprest J, Tritz P, Desjardins I. Development of a clinical prediction score for detection of suspected cases of equine grass sickness (dysautonomia) in France.. Vet Res Commun 2018 Mar;42(1):19-27.
      doi: 10.1007/s11259-017-9704-ypubmed: 29204821google scholar: lookup
    3. Jahns H, Fast C. A histopathological study of bovine ganglia.. J Comp Pathol 2014 Feb-Apr;150(2-3):234-44.
      doi: 10.1016/j.jcpa.2013.11.207pubmed: 24456750google scholar: lookup
    4. Edwards SE, Martz KE, Rogge A, Heinrich M. Edaphic and Phytochemical Factors as Predictors of Equine Grass Sickness Cases in the UK.. Front Pharmacol 2010;1:122.
      doi: 10.3389/fphar.2010.00122pubmed: 21833167google scholar: lookup