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The Veterinary clinics of North America. Equine practice2005; 21(2); 273-v; doi: 10.1016/j.cveq.2005.04.007

Equine neonatal sepsis.

Abstract: Neonatal infection remains a leading cause of morbidity and mortality in the equine industry, despite advances in prevention and treatment. Many factors can influence a foal's risk for the development of sepsis in the peripartum period. This article discusses those factors, causative organisms, and therapeutic options. Factors that influence prognosis and potential preventative strategies also are addressed.
Publication Date: 2005-07-30 PubMed ID: 16051050DOI: 10.1016/j.cveq.2005.04.007Google Scholar: Lookup
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Summary

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This research article investigates the causes, factors, and treatment options for equine neonatal sepsis, which is a leading cause of disease and mortality among newborn foals, even amidst advancements in prevention and therapeutic strategies.

Understanding Equine Neonatal Sepsis

  • The paper focuses on equine neonatal sepsis, an infection that significantly impacts the health and survival of newborn horses.
  • Sepsis, which is a systemic infection often causing a body-wide inflammatory response, remains a pervasive health issue among foals despite scientific and medical progress in its prevention and treatment.

Factors Influencing the Development of Sepsis

  • The article recognizes the various elements that could increase a foal’s susceptibility to developing sepsis during the peripartum period, which is the duration before, during, and immediately after birth.
  • Though the specific factors are not detailed in the abstract, they usually include aspects like the foals’ health status, environmental conditions, the mother’s health, and the adequacy of colostrum intake.

Major Causes and Treatment Options

  • The paper identifies the organisms that are often responsible for causing neonatal sepsis in horses.
  • These causative organisms could include various types of bacteria, viruses, and parasites that may infect the foal during or immediately after birth.
  • The study also explores the different therapeutic strategies available for managing and treating sepsis in equine neonates. The best treatment protocol often involves a combination of antibiotics, supportive care, and sometimes surgery, depending on the severity and cause of the sepsis.

Prognosis and Prevention of Equine Neonatal Sepsis

  • The research article also discusses the influencing factors on the prognosis of equine neonatal sepsis. These factors essentially involve the foal’s overall health, the severity of the infection, and the timeliness and effectiveness of the treatment provided.
  • Additionally, the paper aims to shed light on potential prevention strategies against neonatal sepsis in horses.
  • Generally, preventive methods include ensuring optimal hygiene during the birthing process, adequate colostrum intake, timely vet checks, and prophylactic use of antibiotics.

Cite This Article

APA
Sanchez LC. (2005). Equine neonatal sepsis. Vet Clin North Am Equine Pract, 21(2), 273-v. https://doi.org/10.1016/j.cveq.2005.04.007

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 21
Issue: 2
Pages: 273-v

Researcher Affiliations

Sanchez, L Chris
  • Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100136, 2015 S.W. 16th Avenue, Gainesville, FL 32610-0136, USA. sanchezl@mail.vetmed.ufl.edu

MeSH Terms

  • Animals
  • Animals, Newborn / immunology
  • Anti-Bacterial Agents / therapeutic use
  • Horse Diseases / drug therapy
  • Horse Diseases / epidemiology
  • Horse Diseases / prevention & control
  • Horses
  • Prognosis
  • Risk Factors
  • Sepsis / drug therapy
  • Sepsis / epidemiology
  • Sepsis / prevention & control
  • Sepsis / veterinary
  • Survival Analysis
  • Treatment Outcome

Citations

This article has been cited 13 times.
  1. Scalco R, de Oliveira GN, da Rosa Curcio B, Wooten M, Magdesian KG, Hidai ST, Pandit P, Aleman M. Red blood cell distribution width to platelet ratio in neonatal foals with sepsis. J Vet Intern Med 2023 Jul-Aug;37(4):1552-1560.
    doi: 10.1111/jvim.16793pubmed: 37306395google scholar: lookup
  2. Gomez DE, Wong D, MacNicol J, Dembek K. The fecal bacterial microbiota of healthy and sick newborn foals. J Vet Intern Med 2023 Jan;37(1):315-322.
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  3. Hoeberg E, Sånge A, Saegerman C, Bohlin A, Nostell K, Durie I, Husted L, Öhman A, Jacobsen S, Berg L, Laursen SH, van Galen G. Serum amyloid A as a marker to detect sepsis and predict outcome in hospitalized neonatal foals. J Vet Intern Med 2022 Nov;36(6):2245-2253.
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  4. Michael SA, Hayman DTS, Gray R, Roe WD. Clinical parameters of hypervirulent Klebsiella pneumoniae disease and ivermectin treatment in New Zealand sea lion (Phocarctos hookeri) pups. PLoS One 2022;17(3):e0264582.
    doi: 10.1371/journal.pone.0264582pubmed: 35239682google scholar: lookup
  5. Wollanke B, Gerhards H, Ackermann K. Infectious Uveitis in Horses and New Insights in Its Leptospiral Biofilm-Related Pathogenesis. Microorganisms 2022 Feb 7;10(2).
  6. Müller V, Toribio RE, Dembek K, Moraes BSS, Mousquer MA, Curcio BR, Nogueira CEW. Serum cortisol and thyroid hormone concentrations and survival in foals born from mares with experimentally induced ascending placentitis. J Vet Intern Med 2020 May;34(3):1332-1338.
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    doi: 10.1111/eve.12290pubmed: 32313390google scholar: lookup
  8. Harrison JM, Quanstrom LM, Robinson AR, Wobeser B, Anderson SL, Singh B. Expression of von Willebrand factor, pulmonary intravascular macrophages, and Toll-like receptors in lungs of septic foals. J Vet Sci 2017 Mar 30;18(1):17-23.
    doi: 10.4142/jvs.2017.18.1.17pubmed: 27297419google scholar: lookup
  9. Dembek KA, Hurcombe SD, Frazer ML, Morresey PR, Toribio RE. Development of a likelihood of survival scoring system for hospitalized equine neonates using generalized boosted regression modeling. PLoS One 2014;9(10):e109212.
    doi: 10.1371/journal.pone.0109212pubmed: 25295600google scholar: lookup
  10. Werners AH, Bryant CE. Pattern recognition receptors in equine endotoxaemia and sepsis. Equine Vet J 2012 Jul;44(4):490-8.
  11. Cesarini C, Macieira S, Girard C, Drolet R, d'Anjou MA, Jean D. Costochondral junction osteomyelitis in 3 septic foals. Can Vet J 2011 Jul;52(7):772-7.
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  12. Castagnetti C, Veronesi MC. Prognostic factors in the sick neonatal foal. Vet Res Commun 2008 Sep;32 Suppl 1:S87-91.
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  13. Baek SM, Lee SW, Kim TU, Kim JH, Lee YJ, Yim JH, Kim WJ, Choi SK, Han JE, Jeong KS, Park JK. Case report: Fatal neonatal sepsis associated with Escherichia fergusonii infection in a common bottlenose dolphin (Tursiops truncatus). Front Vet Sci 2023;10:1242599.
    doi: 10.3389/fvets.2023.1242599pubmed: 37822952google scholar: lookup