Equine viral arteritis with abortions: serological and virological evidence in Germany.
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
The research focuses on an outbreak of an equine viral disease in Germany leading to abortions in horses. The study examined the disease both serologically (measurement of antibodies in the blood) and virologically (detection of the virus).
Analysis of Disease Outbreak
In the first part of the paper, the researchers look into an outbreak of a disease presenting clinical features, particularly leading to abortions, among horse populations in Germany. The disease was suspected to be Equine Viral Arteritis (EVA), a contagious disease in horses caused by the Equine Arteritis Virus (EAV).
- EVA is characterized by several clinical symptoms, including fever, depression, loss of appetite, swelling in legs, and, importantly, abortions in mares.
- The disease could be severe in some cases, causing significant economic losses in the equine industry.
Serological and Virological Examination
The research involved serological and virological testing to confirm the presence of EVA.
- Serological examination involves analyzing blood samples for the presence of antibodies specific to the identified pathogen, in this case, EAV. An increasing seropositive rate indicates a growing immune response in the affected animals against the pathogen.
- Virological testing focuses on identifying the virus from samples, which in this case, was achieved by isolating the EAV from an aborted fetus.
- The combination of both tests provides a robust approach for diagnosing the disease.
EVA Prevalence and Need for Control Measures
The study’s findings confirmed EVA’s presence in the German equine population. A significant increase in seropositive horses was noted, indicative of growing prevalence and transmission of the disease among horses.
- Such a situation urges the need for control and prevention measures, given the potential economic impact on the equine industry. These may include vaccination programs, biosecurity measures like isolation of infected animals, and surveillance of the disease.
- This study is crucial to understanding the prevalence of EVA in Germany and emphasizes the importance of ongoing disease surveillance and control measures to mitigate the impacts of such outbreaks.
Cite This Article
Publication
Researcher Affiliations
- Institute for Medical Microbiology, Infectious and Epidemic Diseases, Veterinary Faculty, Ludwig-Maximilians-University, Munich, Germany.
MeSH Terms
- Abortion, Veterinary / epidemiology
- Abortion, Veterinary / virology
- Animals
- Antibodies, Viral / blood
- Arterivirus Infections / epidemiology
- Arterivirus Infections / veterinary
- Arterivirus Infections / virology
- Cell Line
- Chlorocebus aethiops
- Disease Outbreaks / veterinary
- Equartevirus / immunology
- Equartevirus / isolation & purification
- Female
- Horse Diseases / epidemiology
- Horse Diseases / virology
- Horses
- Male
- Pregnancy
- Vero Cells
Citations
This article has been cited 3 times.- Lazić S, Lupulović D, Gaudaire D, Petrovic T, Lazić G, Hans A. Serological evidence of equine arteritis virus infection and phylogenetic analysis of viral isolates in semen of stallions from Serbia. BMC Vet Res 2017 Nov 7;13(1):316.
- Balasuriya UB, Go YY, MacLachlan NJ. Equine arteritis virus. Vet Microbiol 2013 Nov 29;167(1-2):93-122.
- Glaser AL, Chirnside ED, Horzinek MC, de Vries AA. Equine arteritis virus. Theriogenology 1997 Apr 15;47(6):1275-95.