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Evaluation of occlusive dressings for management of full-thickness excisional wounds on the distal portion of the limbs of horses.
Abstract: Two 2.5-cm2 full-thickness skin wounds were created surgically over the lateral aspect of the cannon bone of each limb of 6 horses (n = 48 wounds). Dressings evaluated were a nonadherent gauze pad (group 1); a synthetic semiocclusive dressing, (group 2); equine amnion (group 3); and a synthetic fully occlusive dressing (group 4). Wounds were assessed subjectively at each dressing change, and total wound area, area of granulation tissue, and area of epithelium in each wound were determined by computerized digital analysis of photographs of the wounds. Complete healing time (wound covered by epithelium) also was determined for each wound. Statistical comparisons were made, using Kruskal-Wallis analysis and a Mann-Whitney U test. Median time to complete healing was: group 1, 53 days; group 2, 71 days; group 3, 63 days; and group 4, 113 days. Time to complete healing was significantly longer for wounds of group-4 horses than all other groups, and wounds of group-1 horses healed faster than did those of group-2 horses (P < 0.05). Wounds in group-4 horses required significantly (P < or = 0.05) more excisions of granulation tissue (median, 11.5 times) than did those in group-1 (median, 3.5), group-2 (median, 5.5) or group-3 (median, 2.5) horses. Epithelial tissue was detected later in wounds of group-4 horses (median, 27 days) than in wounds of horses in groups 1, 2 or 3 (median, 17 days); however, this difference was not statistically significant.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Date: 1993-12-01 PubMed ID: 8116952 The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Clinical Trial
- Comparative Study
- Journal Article
- Randomized Controlled Trial
- Research Support
- Non-U.S. Gov't
- Animal Health
- Animal Studies
- Bandaging
- Clinical Examination
- Clinical Findings
- Clinical Pathology
- Clinical Study
- Comparative Study
- Disease Treatment
- Equine Health
- Equine Research
- Equine Wounds
- Granulation Tissue
- Horses
- Observational Study
- Statistical Analysis
- Surgery
- Veterinary Care
- Veterinary Medicine
- Veterinary Procedure
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This study explored the impact of four types of wound dressings on the healing of full-thickness skin wounds on horse limbs. The results showed that nonadherent gauze pads and equine amnion aided faster healing while synthetic fully occlusive dressings prolonged the healing duration.
Methodology
- The research simulated two 2.5-cm2 full-thickness skin wounds per limb on each of the six horses involved in the study, creating a total of 48 wounds.
- Four types of wound dressings were tested in the study. The types were a nonadherent gauze pad, a synthetic semiocclusive dressing, equine amnion, and a synthetic fully occlusive dressing. These were categorized as groups 1 to 4 respectively.
- Each wound’s progress was monitored and assessed at each dressing change.
- Total wound area, area of granulation tissue (new connective tissue and microscopic blood vessels that form on the surface of a wound during the healing process), and the area of epithelium in each wound were determined through computerized digital analysis of wound photographs.
- The complete healing time for every wound was also determined, indicating when the wound was completely covered by epithelium (skin cells).
Results
- Statistics showed that the median time to complete healing was 53 days for group 1 (nonadherent gauze pad), 71 days for group 2 (synthetic semiocclusive dressing), 63 days for group 3(equine amnion), and the longest healing period was for group 4 (synthetic fully occlusive dressing) with 113 days.
- Wounds treated with synthetic fully occlusive dressings (Group 4) took significantly longer to heal than those treated with the other solutions.
- Group-1 horses’ wounds healed more quickly compared to those of group-2.
- Wounds in group-4 horses required more extensive granulation tissue excision (average 11.5 times) compared to groups 1, 2, and 3.
- Epithelial tissue was detected later in wounds of group-4 horses than in wounds of horses in the other groups; however, this difference was not statistically significant.
Conclusions
- This research demonstrates that the type of dressing applied to a full-thickness skin wound can significantly impact the healing time in horses. Nonadherent gauze pads and equine amnion appeared to be the most effective dressings in this study.
- On the other hand, synthetic fully occlusive dressings significantly extended the healing period and required more granulation tissue excision, indicating they are potentially less beneficial for this type of wound in horses.
- These findings can provide guidance for veterinarians in the care and management of full-thickness skin wounds in horses.
Cite This Article
APA
Howard RD, Stashak TS, Baxter GM.
(1993).
Evaluation of occlusive dressings for management of full-thickness excisional wounds on the distal portion of the limbs of horses.
Am J Vet Res, 54(12), 2150-2154.
Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
MeSH Terms
- Animals
- Female
- Granuloma / physiopathology
- Granuloma / therapy
- Granuloma / veterinary
- Hindlimb
- Horse Diseases
- Horses
- Male
- Occlusive Dressings / veterinary
- Orchiectomy
- Skin Diseases / physiopathology
- Skin Diseases / therapy
- Skin Diseases / veterinary
- Wound Healing
- Wounds and Injuries / physiopathology
- Wounds and Injuries / therapy
- Wounds and Injuries / veterinary
Citations
This article has been cited 2 times.- Wise LM, Bodaan CJ, Stuart GS, Real NC, Lateef Z, Mercer AA, Riley CB, Theoret CL. Treatment of limb wounds of horses with orf virus IL-10 and VEGF-E accelerates resolution of exuberant granulation tissue, but does not prevent its development. PLoS One 2018;13(5):e0197223.
- Gomez JH, Schumacher J, Lauten SD, Sartin EA, Hathcock TL, Swaim SF. Effects of 3 biologic dressings on healing of cutaneous wounds on the limbs of horses. Can J Vet Res 2004 Jan;68(1):49-55.
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