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Home / Equine Research Bank / Pharmaceutics / Evaluation of Platonia insignis Mart. (Bacuri Butter) and Bi...
Pharmaceutics2024; 16(11); doi: 10.3390/pharmaceutics16111457

Evaluation of Platonia insignis Mart. (Bacuri Butter) and Biopolymers from the Puree of Allium cepa L. (Yellow Onion Bulb) for Wound Healing in Horses.

Abstract: Background/Objectives: Skin injuries are common in the equine clinical practice, requiring effective treatment to support natural healing. Bacuri butter is gaining attention for its potential in wound healing and its anti-inflammatory, antimicrobial, and antioxidant properties. Natural polymers such as onion (Allium cepa) bioplastics have been investigated for their potential as occlusive dressings and for tissue regeneration. Methods: This study evaluated the healing process of experimentally induced skin wounds on horses treated with bacuri butter, washed onion film, and unwashed onion film. Clinical and histopathological analyses of the wounds were conducted in six clinically healthy horses over 28 days, with a control group receiving Ringer's lactate solution. The onion films were produced and characterized for their chemical structure and properties, while the bacuri butter was sourced and prepared for application. Results: All treatments, including the control group, promoted wound healing without relevant differences in wound contraction rates, gross aspect, or histopathological parameters. Conclusions: Therefore, despite minor variations observed in the clinical evaluations between the treatment groups, the bacuri butter or onion biopolymer showed no significant healing effect on skin wounds in horses. Additionally, this study showed the potential of equine models in testing novel therapeutic approaches for wound healing, benefiting both veterinary and human medicine.
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Publication Date: 2024-11-15 PubMed ID: 39598581PubMed Central: PMC11597205DOI: 10.3390/pharmaceutics16111457Google Scholar: Lookup
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  • Journal Article

Summary

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This research article evaluates the effectiveness of Bacuri butter and onion biopolymers in aiding wound healing in horses.

Objective of the Study

  • The main purpose was to observe the healing process of skin wounds on horses when treated with the Bacuri butter, washed onion film, and unwashed onion film.
  • The study also aimed to assess the potential of these natural substances for wound treatment in veterinary and human medicine.

Methods and Materials

  • Firstly, experimentally induced skin wounds were created on six healthy horses.
  • These wounds were then treated with Bacuri butter, washed onion film, or unwashed onion film over a period of 28 days.
  • For control purposes, a group was treated with Ringer’s lactate solution.
  • The team also produced and characterized onion films for their chemical structure and properties, and sourced and prepared Bacuri butter for application.

Findings of the Study

  • Clinical and histopathological analysis showed that all treatments promoted wound healing on the horses.
  • However, there weren’t any considerable differences in wound contraction rates, visual attributes, or histopathological parameters between the groups.
  • This indicates that the Bacuri butter and onion biopolymer were not significantly more effective for wound healing than the Ringer’s lactate solution in the control group.

Conclusion and Further Implications

  • While Bacuri butter and onion biopolymer did assist in wound healing, the study concluded that they were not significantly better than traditional treatments.
  • Nonetheless, minor variations observed in the clinical evaluations show that there may still be potential for these substances in wound treatment, pending further research.
  • Additionally, this study demonstrated the utility of equine models for testing new therapeutic approaches for wound healing, which can be beneficial for both veterinary and human medicine.

Cite This Article

APA
Resende AM, Miranda BA, Silva LB, Oliveira AB, Castro MB, Macêdo IL, Dallago BSL, Barud HS, Borges MAC, Ribeiro CA, Dias DS, Campebell RC. (2024). Evaluation of Platonia insignis Mart. (Bacuri Butter) and Biopolymers from the Puree of Allium cepa L. (Yellow Onion Bulb) for Wound Healing in Horses. Pharmaceutics, 16(11). https://doi.org/10.3390/pharmaceutics16111457

Publication

Pharmaceutics
ISSN: 1999-4923
NlmUniqueID: 101534003
Country: Switzerland
Language: English
Volume: 16
Issue: 11

Researcher Affiliations

Resende, André M
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Miranda, Beatriz A
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Silva, Luiza B
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Oliveira, Andressa B
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Castro, Márcio B
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Macêdo, Isabel L
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Dallago, Bruno S L
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.
Barud, Hernane S
  • Laboratório de Biopolímeros e Biomateriais (BIOPOLMAT), Departamento de Química, Universidade de Araraquara (UNIARA), Araraquara 14801-320, SP, Brazil.
Borges, Marco A Costa
  • Laboratório de Biopolímeros e Biomateriais (BIOPOLMAT), Departamento de Química, Universidade de Araraquara (UNIARA), Araraquara 14801-320, SP, Brazil.
Ribeiro, Clovis A
  • Departamento de Química Analítica, Fisico-Química e Inorgânica, Instituto de Química, Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Araraquara 14800-060, SP, Brazil.
Dias, Diogenes S
  • Departamento de Química Analítica, Fisico-Química e Inorgânica, Instituto de Química, Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP), Araraquara 14800-060, SP, Brazil.
Campebell, Rita C
  • Hospital Escola de Grandes Animais, Faculdade de Agronomia e Medicina Veterinária (FAV), Universidade de Brasília (UnB), Área Especial SRB, Galpão 4, Granja do Torto, Brasília 70636-200, DF, Brazil.

Conflict of Interest Statement

The authors declare no conflicts of interest.

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