Evaluation of the thoraco-laryngeal reflex (‘slap test’) as an aid to the diagnosis of cervical spinal cord and brainstem disease in horses.
Abstract: A study was conducted over a 12 month period to assess the specificity and sensitivity of the 'slap test', using endoscopic evaluation, in the detection of cervical spinal cord and caudal brainstem lesions in horses. Fifteen ataxic horses were subjected to the 'slap test' and subsequently examined post mortem. Twelve out of the 15 had histopathological lesions consistent with their clinical signs. Thirteen horses with no history of neurological dysfunction and no histopathological evidence of cervical spinal cord or brainstem disease were used as controls. The laryngeal adductory responses exhibited by all horses were filmed and later scored independently by 3 assessors. The proportion of animals diagnosed with cervical spinal cord and/or brainstem disease, defined by histopathological criteria, was found to be statistically similar to the proportion with abnormal 'slap test' responses, using the McNemar chi-Square test. Despite statistical significance between proportions, sensitivity of the 'slap test' was low, 50% for the left side on both days and 58% for the right side. Specificity was higher, 69% (Day 1) and 75% (Day 2) for the left side and 75% (Day 1) and 69% (Day 2) for the right side. In contrast to this, conventional neurological examination was found to be 100% sensitive and 81% specific in the detection of lesions of histopathological significance in the cervical spinal cord/caudal brainstem. Agreement between scores for the 'slap test' from the same assessor on different days was good, with values for kappa of 0.59 to 0.85. In contrast, agreement between assessors on the 'slap test' score was poor, with kappa 0.35.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Date: 1994-09-01 PubMed ID: 7988537DOI: 10.1111/j.2042-3306.1994.tb04403.xGoogle Scholar: Lookup
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- Clinical Trial
- Controlled Clinical Trial
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This research evaluates the ‘slap test’, a diagnostic method for identifying cervical spinal cord and brainstem diseases in horses, by using endoscopic evaluation and comparing it with conventional neurological examination. The study was conducted over a year and had 15 ataxic horses assessed, along with 13 healthy horses for control. Despite statistical significance, the slap test showed low sensitivity but high specificity. The conventional neurological examination was more effective.
Study Design and Procedure
- The study was conducted over a year, with a test group of 15 ataxic horses and a control group of 13 healthy horses.
- Test horses were subjected to the ‘slap test’ — a diagnostic method believed to identify neurological issues in horses.
- Post-mortem examination of the horses was then conducted to confirm the presence of histopathological lesions.
- Responses of all horses were recorded and subsequently reviewed by three independent assessors.
Study Results
- Out of the 15 test horses, 12 were found to have histopathological lesions confirming their clinical signs.
- The correlation between the diagnosis of cervical spinal cord and/or brainstem disease and the response to the ‘slap test’ was statistically equivalent according to the McNemar chi-Square test.
- However, the ‘slap test’ showed low sensitivity (50% for the left side and 58% for the right side).
- The specificity of the ‘slap test’ was higher (around 70% on average).
Comparative Analysis
- Conventional neurological testing of horses showed 100% sensitivity and 81% specificity, proving to be more effective than the ‘slap test’ in the detection of lesions.
- The consistency between each assessor’s own slap test scores on different days was good (kappa values 0.59 to 0.85).
- However, agreement among different assessors on slap test scores was poor (kappa value 0.35), indicating that the slap test might not provide uniform results across different evaluators.
Cite This Article
APA
Newton-Clarke MJ, Divers TJ, Delahunta A, Mohammed HO.
(1994).
Evaluation of the thoraco-laryngeal reflex (‘slap test’) as an aid to the diagnosis of cervical spinal cord and brainstem disease in horses.
Equine Vet J, 26(5), 358-361.
https://doi.org/10.1111/j.2042-3306.1994.tb04403.x Publication
Researcher Affiliations
- New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
MeSH Terms
- Animals
- Brain Diseases / diagnosis
- Brain Diseases / physiopathology
- Brain Diseases / veterinary
- Brain Stem / pathology
- Chi-Square Distribution
- Evaluation Studies as Topic
- Female
- Horse Diseases / diagnosis
- Horse Diseases / physiopathology
- Horses
- Laryngeal Muscles / physiopathology
- Laryngoscopy / veterinary
- Male
- Predictive Value of Tests
- Reflex
- Reproducibility of Results
- Single-Blind Method
- Spinal Cord / pathology
- Spinal Cord / physiopathology
- Spinal Cord Diseases / diagnosis
- Spinal Cord Diseases / physiopathology
- Spinal Cord Diseases / veterinary
- Videotape Recording
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