Exercise-induced pulmonary hemorrhage in Thoroughbreds after racing and breezing.
Abstract: Thoroughbred horses (n = 191) were examined with a flexible fiberoptic endoscope within 2 hours of racing on a dirt track; 147 (75.4%) had evidence of exercise-induced pulmonary hemorrhage (EIPH), and 13 (9.0%) had blood at the nostrils. Of 107 Thoroughbreds examined within the same period after breezing, 41 (38.3%) had evidence of EIPH. One horse (2.4%) of this group had blood at the nostrils. Statistical analysis of frequency data showed that a relationship existed between EIPH and the horse's age or distance raced or breezed. Relationship did not exist between EIPH and sex or finishing position. Thoroughbreds were also examined endoscopically after steeplechase, flat turf, and timber races; 67.7% (21/31), 14.3% (2/14), and 66.6% (2/3) of the horses in such races were EIPH-positive, respectively; and 14.3% (3/21), 0% (0/2), and 100% (2/2) of these EIPH-positive horses had blood at the nostrils. Of 32 breezing Thoroughbreds in a 3rd survey, 21 (65.5%) were EIPH-positive. None bled from the nostrils. Endoscopic findings of EIPH are repeatable in the horses, indicating that bleeding is not a random event.
Publication Date: 1982-07-01 PubMed ID: 7103190
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This study investigates the prevalence of exercise-induced pulmonary hemorrhage (EIPH) in racehorses after participating in different types of races and training exercises. The findings present a significant incidence of EIPH and indicate that the occurrence of this condition relies heavily on the horse’s age and the distance they race or train, with no significant relation to their sex or race outcome.
Study Design and Participants
- The study involved thoroughbred horses that were examined after participating in racing or breezing (a milder form of exercise).
- A total of 191 horses were examined after racing on a dirt track, and 107 horses were examined after breezing.
- Additional thoroughbred horses were also studied after steeplechase, flat turf, and timber races.
Method of Examination
- All horses were examined within two hours of their respective activities using a flexible fiberoptic endoscope. This is a technique used to visualize the internal structures of the body, in this case, the respiratory system, to detect any signs of EIPH.
- The main symptom of EIPH, bleeding from the nostrils, was also closely observed.
Findings
- A significant number of the horses exhibited signs of EIPH, with 75.4% of the racers and 38.3% of the horses that had been breezing showing evidence of this condition. Blood at the nostrils, a clear indication of EIPH, was observed in 9.0% of the EIPH positive racers and 2.4% of the breezing horses.
- After the steeplechase, flat turf, and timber races, 67.7%, 14.3%, and 66.6% of the horses respectively were EIPH-positive. The percentage of these EIPH-positive horses that had blood at the nostrils was 14.3%, 0%, and 100%, respectively.
- In a third survey involving 32 breezing Thoroughbreds, 65.5% were found to be EIPH-positive. None of these horses exhibited blood from the nostrils.
- Statistical analysis showed a relationship existed between the incidence of EIPH and factors such as the horse’s age or distance they raced or breezed. However, no significant relationship was found between EIPH and sex or race outcome.
- The study also notes that endoscopic findings of EIPH are repeatable in horses, signifying that EIPH occurrence is not a random event but may be related to specific triggers or predisposing factors.
Cite This Article
APA
Raphel CF, Soma LR.
(1982).
Exercise-induced pulmonary hemorrhage in Thoroughbreds after racing and breezing.
Am J Vet Res, 43(7), 1123-1127.
Publication
Researcher Affiliations
MeSH Terms
- Age Factors
- Animals
- Endoscopy / veterinary
- Female
- Fiber Optic Technology
- Hemorrhage / epidemiology
- Hemorrhage / etiology
- Hemorrhage / veterinary
- Horse Diseases / epidemiology
- Horse Diseases / etiology
- Horses
- Lung Diseases / epidemiology
- Lung Diseases / etiology
- Lung Diseases / veterinary
- Male
- Pennsylvania
- Physical Exertion
- Sex Factors
Citations
This article has been cited 13 times.- Sugiyama F, Takahashi Y, Nomura M, Ebisuda Y, Mukai K, Yoshida T. Risk Factors for Epistaxis in Thoroughbred Flat Races in Japan (2001-2020). Animals (Basel) 2023 Apr 14;13(8).
- Lo Feudo CM, Stucchi L, Stancari G, Alberti E, Conturba B, Zucca E, Ferrucci F. Associations between Exercise-Induced Pulmonary Hemorrhage (EIPH) and Fitness Parameters Measured by Incremental Treadmill Test in Standardbred Racehorses. Animals (Basel) 2022 Feb 12;12(4).
- Dahlgren AR, Tablin F, Finno CJ. Genetics of equine bleeding disorders. Equine Vet J 2021 Jan;53(1):30-37.
- Lopez Sanchez CM, Kogan C, Gold JR, Sellon DC, Bayly WM. Relationship between tracheobronchoscopic score and bronchoalveolar lavage red blood cell numbers in the diagnosis of exercise-induced pulmonary hemorrhage in horses. J Vet Intern Med 2020 Jan;34(1):322-329.
- Poole DC, Erickson HH. Exercise-induced pulmonary hemorrhage: where are we now?. Vet Med (Auckl) 2016;7:133-148.
- Barton AK, Gehlen H. Pulmonary Remodeling in Equine Asthma: What Do We Know about Mediators of Inflammation in the Horse?. Mediators Inflamm 2016;2016:5693205.
- Hinchcliff KW, Couetil LL, Knight PK, Morley PS, Robinson NE, Sweeney CR, van Erck E. Exercise induced pulmonary hemorrhage in horses: American College of Veterinary Internal Medicine consensus statement. J Vet Intern Med 2015 May-Jun;29(3):743-58.
- Hackett RP, Ducharme NG, Gleed RD, Mitchell L, Soderholm LV, Erickson BK, Erb HN. Do Thoroughbred and Standardbred horses have similar increases in pulmonary vascular pressures during exertion?. Can J Vet Res 2003 Oct;67(4):291-6.
- Doucet MY, Viel L. Clinical, radiographic, endoscopic, bronchoalveolar lavage and lung biopsy findings in horses with exercise-induced pulmonary hemorrhage. Can Vet J 2002 Mar;43(3):195-202.
- Guthrie AJ, Beadle RE, Bateman RD, White CE. The effects of three models of airway disease on tidal breathing flow-volume loops of thoroughbred horses. Vet Res Commun 1995;19(6):517-27.
- Littlejohn A, Howell W, Killeen V. Pulmonary arterial haemodynamics and blood gas values of Thoroughbred racehorses with a history of epistaxis during a race. Vet Res Commun 1984 Feb;8(1):41-5.
- Donaldson LL. A review of the pathophysiology of exercise-induced pulmonary haemorrhage in the equine athlete. Vet Res Commun 1991;15(3):211-26.
- Nath LC, Elliott A, La Gerche A, Weir J, Forbes G, Thomas G, Franklin S. Associations between postrace atrial fibrillation and measures of performance, racing history and airway disease in horses. J Vet Intern Med 2023 Nov-Dec;37(6):2573-2583.
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