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Journal of the American Veterinary Medical Association2018; 252(9); 1113-1119; doi: 10.2460/javma.252.9.1113

Factors associated with postoperative complications in healthy horses after general anesthesia for ophthalmic versus non-ophthalmic procedures: 556 cases (2012-2014).

Abstract: OBJECTIVE To compare complications between healthy horses undergoing general anesthesia for ophthalmic versus non-ophthalmic procedures and identify potential risk factors for the development of complications. DESIGN Retrospective case series. ANIMALS 502 horses (556 anesthetic procedures). PROCEDURES Medical records from January 2012 through December 2014 were reviewed to identify horses undergoing general anesthesia. Signalment, body weight, drugs administered, patient positioning, procedure type (ophthalmic, orthopedic, soft tissue, or diagnostic imaging), specific procedure, procedure time, anesthesia time, recovery time, recovery quality, and postoperative complications were recorded. RESULTS Patients underwent general anesthesia for ophthalmic (n = 106), orthopedic (246), soft tissue (84), diagnostic imaging (110), or combined (10) procedures. Mean procedure, anesthesia, and recovery times were significantly longer for patients undergoing ophthalmic versus non-ophthalmic procedures. Excluding diagnostic imaging procedures, there was a significant positive correlation between surgery time and recovery time. Within ophthalmic procedures, surgery time, anesthesia time, and recovery time were significantly greater for penetrating keratoplasty versus other ophthalmic procedures. There was a significantly higher rate of postoperative colic following penetrating keratoplasty, compared with all other ophthalmic procedures. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that in healthy horses, duration of general anesthesia should be minimized to decrease the risk of postanesthetic complications. Judicious use of orally administered fluconazole is recommended for horses undergoing general anesthesia. For horses undergoing a retrobulbar nerve block during general anesthesia, use of the lowest effective volume is suggested.
Publication Date: 2018-04-12 PubMed ID: 29641332DOI: 10.2460/javma.252.9.1113Google Scholar: Lookup
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  • Journal Article

Summary

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This research article examines the complications experienced by healthy horses after general anesthesia for different surgical procedures, particularly focusing on ophthalmic (eye-related) procedures. The study identifies potential risk factors for these complications and suggests ways to mitigate them.

Study Design and Procedures

  • The study is designed as a retrospective case series, where the researches reviewed previously recorded data.
  • Medical records of 502 horses, amounting to 556 anesthetic procedures, from January 2012 through December 2014 were reviewed.
  • Data collected included the characteristic of the horse (signalment), body weight, drugs administered during the surgery, patient positioning, the type of procedure, specific procedure details, procedure time, anesthesia time, recovery time & quality, and any postoperative complications.

Findings of the Study

  • The horses had undergone general anesthesia procedures for ophthalmic (eye-related), orthopedic, soft tissue, diagnostic imaging, or combined procedures.
  • The research found that on average, procedure time, anesthesia duration, and recovery time were longer for patients undergoing ophthalmic versus non-ophthalmic procedures.
  • Excluding diagnostic imaging procedures, there was a significant positive correlation between the duration of the surgery and the recovery time, meaning longer surgeries corresponded to longer recovery times.
  • Within ophthalmic procedures, surgery time, anesthesia time, and recovery time were longer for a specific procedure called penetrating keratoplasty versus other ophthalmic procedures.
  • There was a higher incidence of postoperative colic (abdominal pain) following penetrating keratoplasty, compared with all other ophthalmic procedures.

Conclusions and Clinical Relevance

  • The results suggest that in healthy horses, the duration of general anesthesia should be kept as short as possible to decrease the risk of postanesthetic complications.
  • The study recommends the cautious use of the antifungal medication fluconazole, administered orally, for horses undergoing general anesthesia.
  • For horses undergoing a retrobulbar nerve block during general anesthesia, a procedure where anesthetics are injected into the area behind the eye, the researchers suggest that the lowest effective volume of anesthetic should be used.

Cite This Article

APA
Curto EM, Griffith EH, Posner LP, Walsh KT, Balko JA, Gilger BC. (2018). Factors associated with postoperative complications in healthy horses after general anesthesia for ophthalmic versus non-ophthalmic procedures: 556 cases (2012-2014). J Am Vet Med Assoc, 252(9), 1113-1119. https://doi.org/10.2460/javma.252.9.1113

Publication

ISSN: 1943-569X
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 252
Issue: 9
Pages: 1113-1119

Researcher Affiliations

Curto, Elizabeth M
    Griffith, Emily H
      Posner, Lysa P
        Walsh, Kaitlyn T
          Balko, Julie A
            Gilger, Brian C

              MeSH Terms

              • Anesthesia Recovery Period
              • Anesthesia, General / veterinary
              • Animals
              • Colic / veterinary
              • Eye Diseases / surgery
              • Eye Diseases / veterinary
              • Female
              • Horse Diseases / surgery
              • Horses
              • Male
              • Ophthalmologic Surgical Procedures / veterinary
              • Postoperative Complications / veterinary
              • Records / veterinary
              • Treatment Outcome

              Citations

              This article has been cited 7 times.
              1. Szewczyk AM, Fernandez Barrientos MA, Bradbrook C. Anaesthetic Complications in Dogs Undergoing Total Ear Canal Ablation and Ventral Bulla Osteotomy: A Single-Centre Retrospective Study. Animals (Basel) 2025 May 13;15(10).
                doi: 10.3390/ani15101401pubmed: 40427278google scholar: lookup
              2. Holz N, Suárez J, Hetzel U, Rampazzo A, Stoppini R. Mycotic Sphenopalatine Sinusitis With Concurrent Compression of the Optic Nerves and Chiasm and Severe Visual Impairment in A Horse. Vet Ophthalmol 2026 Jan;29(1):e70003.
                doi: 10.1111/vop.70003pubmed: 40055139google scholar: lookup
              3. Brandenberger O, Kalinovskiy A, Körner J, Genn H, Burger R, Leser S. Effect of Bio-Electro-Magnetic-Energy-Regulation (BEMER) Horse Therapy on Cardiopulmonary Function and Recovery Quality After Isoflurane Anesthesia in 100 Horses Subjected to Pars-Plana Vitrectomy: An Investigator-Blinded Clinical Study. Animals (Basel) 2024 Dec 18;14(24).
                doi: 10.3390/ani14243654pubmed: 39765558google scholar: lookup
              4. Young K, Hasegawa T, Vridhachalam N, Henderson N, Salmon JH, McCall TF, Hirsch ML, Gilger BC. Ocular toxicity, distribution, and shedding of intravitreal AAV-eqIL-10 in horses. Mol Ther Methods Clin Dev 2024 Dec 12;32(4):101360.
                doi: 10.1016/j.omtm.2024.101360pubmed: 39703903google scholar: lookup
              5. Manning H, Sampson S. Peri-anaesthetic complications in 1798 equids undergoing high-field elective orthopaedic MRI at a tertiary referral hospital. Equine Vet J 2025 May;57(3):666-673.
                doi: 10.1111/evj.14208pubmed: 39143703google scholar: lookup
              6. Jodzio D, DeNotta S, Plummer C, Sanchez C. Pain scoring systems in hospitalized horses with ocular disease. J Vet Intern Med 2024 Jan-Feb;38(1):388-397.
                doi: 10.1111/jvim.16933pubmed: 37982362google scholar: lookup
              7. Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature. Animals (Basel) 2021 Jun 14;11(6).
                doi: 10.3390/ani11061777pubmed: 34198637google scholar: lookup