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Equine veterinary journal. Supplement2012; (41); 113-119; doi: 10.1111/j.2042-3306.2011.00452.x

Factors influencing placental development and function in the mare.

Abstract: The development of the equine placenta involves a series of stage-specific events which ensure that the fetus is nourished throughout its 11 months of gestation. Initially, placental exchange to the developing embryo is histotrophic, via the yolk sac but, as the allantochorion develops and microcotyledons form, haemotrophic nutrition plays the major role in sustaining the increasing demands of the growing fetus. This review describes the development of the allantochorionic placenta of the mare and discusses some of the factors that influence its growth, size and functions and, hence, its control of fetal growth and maturation.
Publication Date: 2012-05-19 PubMed ID: 22594039DOI: 10.1111/j.2042-3306.2011.00452.xGoogle Scholar: Lookup
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  • Journal Article
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  • Non-U.S. Gov't
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article gives an in-depth analysis of how the placenta of a horse develops and functions, as well as the elements that have an impact on its growth, size, and function, thereby controlling the growth and maturation of the foetus.

Placental Development in Mares

This research paper is primarily focused on the developmental journey of the placenta in female horses (mares). The following points provide insight into the specifics of this development:

  • The placental development involves a series of stage-specific events to provide nutrition to the fetus over its 11-month gestation period.
  • Initially, the placental exchange to the embryo is via the yolk sac, a process referred to as histotrophic nutrition.
  • As the allantochorion develops and microcotyledons form, the mode of nutrition shifts to haemotrophic, playing a major role in meeting the growing nutritional demands of the fetus.

Factors Influencing Placental Growth and Functions

The research article not only provides insight into the development of the equine placenta, it also delves into factors influencing its growth, size, and functions. This is significant as it ultimately affects fetal growth and maturation. Key factors discussed are:

  • The development of the allantochorionic placenta: This is a crucial stage in which the mare’s placenta forms numerous microscopic cotyledons that expand its surface area, enabling better absorption of nutrients and oxygen for the fetus.
  • Size of the placenta: The size of the placenta influences the size of the foetus. Larger placentas can provide more nutrition, supporting the growth of a larger foetus.
  • Various unspecified environmental and genetic factors: The study suggests that the growth, size, and function of a mare’s placenta are influenced by both genetic and environmental factors, although the specifics are not detailed in the abstract.

Cite This Article

APA
Wilsher S, Allen WR. (2012). Factors influencing placental development and function in the mare. Equine Vet J Suppl(41), 113-119. https://doi.org/10.1111/j.2042-3306.2011.00452.x

Publication

NlmUniqueID: 9614088
Country: United States
Language: English
Issue: 41
Pages: 113-119

Researcher Affiliations

Wilsher, S
  • The Paul Mellon Laboratory of Equine Reproduction, Newmarket, Suffolk, UK. pml@binternet.com
Allen, W R

    MeSH Terms

    • Animal Nutritional Physiological Phenomena
    • Animals
    • Female
    • Horses / physiology
    • Maternal Nutritional Physiological Phenomena
    • Placenta / physiology
    • Placenta / ultrastructure
    • Placentation
    • Pregnancy

    Citations

    This article has been cited 5 times.
    1. Satué K, La Fauci D, Medica P, Damiá Gímenez E, Cravana C, Fazio E. Shifts between pro-inflammatory and anti-inflammatory profiles in pregnant mares: a review of physiological functions. Front Vet Sci 2025;12:1660759.
      doi: 10.3389/fvets.2025.1660759pubmed: 41049139google scholar: lookup
    2. Peere S, Van den Branden E, Broothaers K, Polfliet E, Smits K, Govaere J. Birth of a Healthy Monozygotic Twin Foal with Hydrops and a Dead Co-Twin. Vet Sci 2024 Dec 13;11(12).
      doi: 10.3390/vetsci11120649pubmed: 39728989google scholar: lookup
    3. Zdrojkowski Ł, Pawliński B, Skierbiszewska K, Jasiński T, Domino M. Assessment of Connective Tissue in the Equine Uterus and Cervix: Review of Clinical Impact and Staining Options. Animals (Basel) 2024 Jan 3;14(1).
      doi: 10.3390/ani14010156pubmed: 38200887google scholar: lookup
    4. Katila T, Ferreira-Dias G. Evolution of the Concepts of Endometrosis, Post Breeding Endometritis, and Susceptibility of Mares. Animals (Basel) 2022 Mar 19;12(6).
      doi: 10.3390/ani12060779pubmed: 35327176google scholar: lookup
    5. Neto da Silva AC, Costa AL, Teixeira A, Alpoim-Moreira J, Fernandes C, Fradinho MJ, Rebordão MR, Silva E, Ferreira da Silva J, Bliebernicht M, Alexandre-Pires G, Ferreira-Dias G. Collagen and Microvascularization in Placentas From Young and Older Mares. Front Vet Sci 2021;8:772658.
      doi: 10.3389/fvets.2021.772658pubmed: 35059454google scholar: lookup