Factors influencing placental development and function in the mare.
- Journal Article
- Research Support
- Non-U.S. Gov't
- Review
Summary
The research article gives an in-depth analysis of how the placenta of a horse develops and functions, as well as the elements that have an impact on its growth, size, and function, thereby controlling the growth and maturation of the foetus.
Placental Development in Mares
This research paper is primarily focused on the developmental journey of the placenta in female horses (mares). The following points provide insight into the specifics of this development:
- The placental development involves a series of stage-specific events to provide nutrition to the fetus over its 11-month gestation period.
- Initially, the placental exchange to the embryo is via the yolk sac, a process referred to as histotrophic nutrition.
- As the allantochorion develops and microcotyledons form, the mode of nutrition shifts to haemotrophic, playing a major role in meeting the growing nutritional demands of the fetus.
Factors Influencing Placental Growth and Functions
The research article not only provides insight into the development of the equine placenta, it also delves into factors influencing its growth, size, and functions. This is significant as it ultimately affects fetal growth and maturation. Key factors discussed are:
- The development of the allantochorionic placenta: This is a crucial stage in which the mare’s placenta forms numerous microscopic cotyledons that expand its surface area, enabling better absorption of nutrients and oxygen for the fetus.
- Size of the placenta: The size of the placenta influences the size of the foetus. Larger placentas can provide more nutrition, supporting the growth of a larger foetus.
- Various unspecified environmental and genetic factors: The study suggests that the growth, size, and function of a mare’s placenta are influenced by both genetic and environmental factors, although the specifics are not detailed in the abstract.
Cite This Article
Publication
Researcher Affiliations
- The Paul Mellon Laboratory of Equine Reproduction, Newmarket, Suffolk, UK. pml@binternet.com
MeSH Terms
- Animal Nutritional Physiological Phenomena
- Animals
- Female
- Horses / physiology
- Maternal Nutritional Physiological Phenomena
- Placenta / physiology
- Placenta / ultrastructure
- Placentation
- Pregnancy
Citations
This article has been cited 5 times.- Satué K, La Fauci D, Medica P, Damiá Gímenez E, Cravana C, Fazio E. Shifts between pro-inflammatory and anti-inflammatory profiles in pregnant mares: a review of physiological functions. Front Vet Sci 2025;12:1660759.
- Peere S, Van den Branden E, Broothaers K, Polfliet E, Smits K, Govaere J. Birth of a Healthy Monozygotic Twin Foal with Hydrops and a Dead Co-Twin. Vet Sci 2024 Dec 13;11(12).
- Zdrojkowski Ł, Pawliński B, Skierbiszewska K, Jasiński T, Domino M. Assessment of Connective Tissue in the Equine Uterus and Cervix: Review of Clinical Impact and Staining Options. Animals (Basel) 2024 Jan 3;14(1).
- Katila T, Ferreira-Dias G. Evolution of the Concepts of Endometrosis, Post Breeding Endometritis, and Susceptibility of Mares. Animals (Basel) 2022 Mar 19;12(6).
- Neto da Silva AC, Costa AL, Teixeira A, Alpoim-Moreira J, Fernandes C, Fradinho MJ, Rebordão MR, Silva E, Ferreira da Silva J, Bliebernicht M, Alexandre-Pires G, Ferreira-Dias G. Collagen and Microvascularization in Placentas From Young and Older Mares. Front Vet Sci 2021;8:772658.