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BMC veterinary research2019; 15(1); 78; doi: 10.1186/s12917-019-1829-5

Feasibility of a disposable canister-free negative-pressure wound therapy (NPWT) device for treating open wounds in horses.

Abstract: Wounds are among the most common medical conditions affecting horses and have a major economic impact on the horse industry. Wound healing in horses is distinct to that documented in other species, and often results in delayed healing and extensive scarring, with compromised functional and aesthetic outcomes. To date, there is no conventional method objectively proven to accelerate healing or to successfully prevent complications associated with second intention healing. Several effects of Negative Pressure Wound Therapy (NPWT) may be particularly useful to the management of wounds in horses. However, cumbersome designs of classic NPWT devices render them unsuitable for equine practice. A new lightweight, portable and disposable unit of NPWT (PICO®), should facilitate the use of this modality by equine practitioners. The aim of this study was to evaluate the feasibility of using this canister-free system to treat experimental open wounds in horses. Results: No difficulties were encountered with the application or maintenance of the PICO® system during the ex vivo experiment or during the preliminary in vivo experiment conducted on intact skin. All horses readily tolerated the PICO® but difficulties with adhesion and seal prevented the completion of the experimental wound study despite the use of many adjunctive adhesives. Conclusions: The current PICO® dressing design is not suitable to be used as a dressing for open wounds in horses though the device is well tolerated by equine patients. A dressing with a wider adhesive edge, a superior adhesive and a more flexible pad would likely be better adapted to enable its future use in equine practice.
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Publication Date: 2019-03-06 PubMed ID: 30841889PubMed Central: PMC6404353DOI: 10.1186/s12917-019-1829-5Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article centers on the practicality of a disposable canister-free negative-pressure wound therapy (NPWT) device for treating wounds in horses. The researchers concluded that while horses well tolerated the device, its current design is unsuitable due to issues with adhesion and seal, suggesting modifications for future use.

Introduction to the Study

  • The study evaluates the feasibility of a portable, disposable NPWT device, PICO®, for treating open wounds in horses.
  • Negative Pressure Wound Therapy (NPWT) is identified as potentially beneficial to wound management in horses, yet typical NPWT devices are not appropriate for equine practice due to their bulky designs.

Methodology of the Study

  • The researchers conducted both an ex vivo (outside of a living organism) and a preliminary in vivo (within a living organism) experiment to assess the device’s applicability.
  • The study further evaluated the horse’s tolerance of the PICO® system, as well as application and maintenance issues.

Results of the Study

  • In terms of applying and maintaining the PICO® system, the researchers experienced no issues during ex vivo experiments or in vivo experiments on intact skin.
  • All horses tolerated the PICO® system. However, problems with the adhesion and sealing of the device hindered the completion of the experimental wound study, even with the use of additional adhesives.

Conclusion of the Study

  • The superiority of the PICO® system’s current design was found to be lacking significantly for use as a dressing for open wounds on horses, despite being well-tolerated by the animals.
  • The researchers suggest improvements to the dressing, such as a wider adhesive edge, a more robust adhesive, and a more flexible pad, would make the device more suitable for future use in equine practice.

Cite This Article

APA
Kamus L, Rameau M, Theoret C. (2019). Feasibility of a disposable canister-free negative-pressure wound therapy (NPWT) device for treating open wounds in horses. BMC Vet Res, 15(1), 78. https://doi.org/10.1186/s12917-019-1829-5

Publication

BMC veterinary research
ISSN: 1746-6148
NlmUniqueID: 101249759
Country: England
Language: English
Volume: 15
Issue: 1
Pages: 78

Researcher Affiliations

Kamus, Louis
  • Département de biomédecine vétérinaire, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, QC, J2S 2M2, Canada. louis.j.kamus@umontreal.ca.
Rameau, Marie
  • Département de biomédecine vétérinaire, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, QC, J2S 2M2, Canada.
Theoret, Christine
  • Département de biomédecine vétérinaire, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, QC, J2S 2M2, Canada.

MeSH Terms

  • Adhesives / adverse effects
  • Animals
  • Bandages / adverse effects
  • Bandages / veterinary
  • Equipment Design / veterinary
  • Female
  • Horses / injuries
  • Negative-Pressure Wound Therapy / instrumentation
  • Negative-Pressure Wound Therapy / veterinary
  • Wound Healing
  • Wounds and Injuries / therapy
  • Wounds and Injuries / veterinary

Grant Funding

  • 2881 / American College of Veterinary Surgeons Foundation

Conflict of Interest Statement

ETHICS APPROVAL AND CONSENT TO PARTICIPATE: The protocol was evaluated and approved by the ethics board on animal use of the Université de Montréal, which follows the guidelines of the Canadian Council on Animal Care (approval # 15-Rech-1811). CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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Citations

This article has been cited 2 times.
  1. Cantatore F, Pagliara E, Marcatili M, Bertuglia A. Negative-Pressure Wound Therapy (NPWT) in Horses: A Scoping Review. Vet Sci 2023 Aug 6;10(8).
    doi: 10.3390/vetsci10080507pubmed: 37624295google scholar: lookup
  2. Dubuc V, Laverty S, Richard H, Doré M, Theoret C. Development of a computer-based quantification method for immunohistochemically-stained tissues and its application to study mast cells in equine wound healing (proof of concept). BMC Vet Res 2020 Jul 2;16(1):228.
    doi: 10.1186/s12917-020-02444-xpubmed: 32616050google scholar: lookup
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