Fell Pony syndrome in a pony in North America.
Abstract: A 5-week-old Fell Pony colt was examined for fever, lethargy, and anemia. The colt had been lethargic for 1 week before examination, had continued to nurse, had a temperature of 104°F (40°C), and was treated with ceftiofur (5 mg/kg IM q12h). Approximately 36 hours before examination, the colt developed watery diarrhea. Blood work performed by the referring veterinarian on the day of admission revealed a PCV of 10%.
Publication Date: 2006-02-25 PubMed ID: 16496942DOI: 10.1892/0891-6640(2006)20[198:fpsiap]2.0.co;2Google Scholar: Lookup
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- Case Reports
- Journal Article
- Case Reports
- Clinical Symptoms
- Diagnosis
- Disease
- Disease control
- Disease Diagnosis
- Disease Etiology
- Disease Management
- Disease Outbreaks
- Disease Prevention
- Disease Surveillance
- Disease Transmission
- Disease Treatment
- Equine Diseases
- Equine Health
- Genetics
- Horses
- Pony
- Veterinary Care
- Veterinary Medicine
- Veterinary Research
Summary
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The study examines a case of Fell Pony Syndrome (FPS) in a 5-week-old colt in North America, who presented symptoms of fever, lethargy, anemia and subsequently watery diarrhea. FPS is an inherited disease that primarily affects the breed, leading to severe anemia and other complications.
Background
- Fell Pony Syndrome (FPS) is an inherited illness that primarily impacts Fell Ponies, a type of horse bred in Northern England. The disease is often fatal and has symptoms such as lethargy, fever, and severe anemia.
- In this study, a case of a 5-week-old Fell Pony colt with the disease is presented. The case reportedly occurred in North America, which makes it a unique observation, given the Fell Pony breed’s geographical origins.
Clinical Examination
- The young colt turned lethargic a week before examination and was found with a high temperature of 104°F (40°C). Despite its condition, the colt continued to nurse.
- The pony was administered ceftiofur, an antibiotic used in horses, at a dose of 5 mg/kg twice daily. Ceftiofur was likely provided to manage potential bacterial infections given the pony’s fever.
- Approximately 36 hours before the examination, the colt developed watery diarrhea, a symptom not generally associated with FPS, suggesting potential complications or secondary infections.
Diagnostic Tests
- A referring veterinarian performed blood work on the day of admission and found severe levels of anemia in the colt as its packed cell volume (PCV) was only at 10%. PCV measures the percentage of red blood cells in the blood and a low PCV indicates anemia.
- Severe anemia is a typical symptom of FPS, and alongside the other symptoms presented and the colt’s breed, this significantly suggested the likelihood of FPS.
Cite This Article
APA
Gardner RB, Hart KA, Stokol T, Divers TJ, Flaminio MJ.
(2006).
Fell Pony syndrome in a pony in North America.
J Vet Intern Med, 20(1), 198-203.
https://doi.org/10.1892/0891-6640(2006)20[198:fpsiap]2.0.co;2 Publication
Researcher Affiliations
- Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
MeSH Terms
- Anemia / diagnosis
- Anemia / veterinary
- Animals
- Animals, Newborn
- Bone Marrow / pathology
- Horse Diseases / diagnosis
- Horse Diseases / drug therapy
- Horse Diseases / pathology
- Horses
- Lymph Nodes / pathology
- Male
- North America
- Spleen / pathology
- Syndrome
Citations
This article has been cited 3 times.- Tallmadge RL, Stokol T, Gould-Earley MJ, Earley E, Secor EJ, Matychak MB, Felippe MJ. Fell Pony syndrome: characterization of developmental hematopoiesis failure and associated gene expression profiles. Clin Vaccine Immunol 2012 Jul;19(7):1054-64.
- Brosnahan MM, Brooks SA, Antczak DF. Equine clinical genomics: A clinician's primer. Equine Vet J 2010 Oct;42(7):658-70.
- Flaminio MJ, Tallmadge RL, Salles-Gomes CO, Matychak MB. Common variable immunodeficiency in horses is characterized by B cell depletion in primary and secondary lymphoid tissues. J Clin Immunol 2009 Jan;29(1):107-16.
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