First isolation of Bunyamwera virus (Bunyaviridae family) from horses with neurological disease and an abortion in Argentina.
Abstract: Bunyamwera virus (BUNV) is the prototype virus for both the Orthobunyavirus genus and the Bunyaviridae family. Different strains of BUNV have been associated with clinical diseases in domestic animals, mainly ruminants. During 2013, in Argentina's Santa Fe Province, three new isolates of BUNV were recovered from the brain and spleen of two horses with encephalitis, and from the brain of an aborted equine fetus. This isolation of BUNV from domestic animals provided the first association of BUNV infection with disease of the central nervous system and abortion in equines in Argentina.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Publication Date: 2015-06-25 PubMed ID: 26183295DOI: 10.1016/j.tvjl.2015.06.013Google Scholar: Lookup
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Summary
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The article documents the first instance in Argentina where the Bunyamwera virus (BUNV), usually found in ruminants, was isolated from horses showing signs of neurological disease and an aborted equine fetus.
Background
- The article provides background information on Bunyamwera virus (BUNV), which is the primary strain of virus for the Orthobunyavirus genus and the Bunyaviridae family. Historically, this type of virus has most commonly been linked to diseases in domestic animals, primarily ruminants.
Recent Findings
- The study faced a unique circumstance in 2013 when, in Santa Fe Province of Argentina, BUNV was isolated from two horses exhibiting signs of encephalitis, a type of brain inflammation that leads to altered function and potentially severe neurological disease.
- The virus was also found in the brain of a horse fetus that had been aborted, presenting another first-time observation for researchers.
Significance and Implications
- The significance of these findings is twofold—firstly, this is the initial documented instance of BUNV being associated with neurological disease in horses. Secondly, it’s the first known case where BUNV has been related to equine abortion.
- This suggests a potential expansion of the virus’s host range or alteration in its potency, both of which have important implications for animal health and disease control initiatives.
- The discovery is especially important in Argentina, where the local agriculture sector relies heavily on healthy horse populations. It can also provide useful insights to assist in veterinary disease control and management across the globe.
Cite This Article
APA
Tauro LB, Rivarola ME, Lucca E, Mariño B, Mazzini R, Cardoso JF, Barrandeguy ME, Teixeira Nunes MR, Contigiani MS.
(2015).
First isolation of Bunyamwera virus (Bunyaviridae family) from horses with neurological disease and an abortion in Argentina.
Vet J, 206(1), 111-114.
https://doi.org/10.1016/j.tvjl.2015.06.013 Publication
Researcher Affiliations
- Laboratorio de Arbovirus, Instituto de Virología Dr. J.M. Vanella, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, CP: X5016 GRA Ciudad Universitaria, Córdoba, Argentina. Electronic address: lauratauro@gmail.com.
- Laboratorio de Arbovirus, Instituto de Virología Dr. J.M. Vanella, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, CP: X5016 GRA Ciudad Universitaria, Córdoba, Argentina.
- Cátedra de Enfermedades Infecciosas, Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, RP Kreder 2805, S3080HOF Esperanza, Santa Fe, Argentina.
- Catedra de Microbiologia, Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, RP Kreder 2805, S3080HOF Esperanza, Santa Fe, Argentina.
- Cátedra de Practicas Hospitalarias de Grandes Animales, Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, Nacional del Litoral, RP Kreder 2805, S3080HOF Esperanza, Santa Fe, Argentina.
- Centro de Inovações Tecnológicas, Instituto Evandro Chagas, Ministério da Saúde, Rodovia BR-316 km 7 s/n, Levilândia, Ananindeua, 67030-000 PA, Brazil.
- Instituto de Virología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto de Tecnología Agropecuaria, Las Cabañas y Los Reseros s/n, Castelar, 1712 Buenos Aires, Argentina.
- Centro de Inovações Tecnológicas, Instituto Evandro Chagas, Ministério da Saúde, Rodovia BR-316 km 7 s/n, Levilândia, Ananindeua, 67030-000 PA, Brazil.
- Laboratorio de Arbovirus, Instituto de Virología Dr. J.M. Vanella, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo Gómez s/n, CP: X5016 GRA Ciudad Universitaria, Córdoba, Argentina.
MeSH Terms
- Aborted Fetus / virology
- Animals
- Argentina / epidemiology
- Bunyamwera virus / genetics
- Bunyamwera virus / isolation & purification
- Bunyaviridae Infections / epidemiology
- Bunyaviridae Infections / veterinary
- Bunyaviridae Infections / virology
- Encephalitis, Viral / epidemiology
- Encephalitis, Viral / veterinary
- Encephalitis, Viral / virology
- Horse Diseases / epidemiology
- Horse Diseases / virology
- Horses
- Phylogeny
Citations
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