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The Veterinary clinics of North America. Equine practice2008; 24(1); 153-175; doi: 10.1016/j.cveq.2007.11.008

Future tools for early diagnosis and monitoring of musculoskeletal injury: biomarkers and CT.

Abstract: This article provides an overview of two relatively new techniques that can be used for the early detection of musculoskeletal injury: biochemical markers and CT. The emphasis in the biomarker section is on the early detection of joint disorders because these are most important clinically and most of the research has been conducted in this area. In the section on CT, bone is the target tissue.
Publication Date: 2008-03-04 PubMed ID: 18314041DOI: 10.1016/j.cveq.2007.11.008Google Scholar: Lookup
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Summary

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The research article focuses on the development and potential of two non-invasive techniques for early detection of musculoskeletal injuries, namely biomarkers and CT (Computed Tomography) scans, with a specific interest in joint disorders and bone health.

Biomarkers for early detection of joint disorders

  • The research emphasizes biomarkers, biochemical entities found in blood, other bodily fluids, or tissues, which can indicate the existence of certain medical conditions.
  • In terms of musculoskeletal injuries, biomarkers are particularly relevant for early detection of joint disorders. Joint disorders such as arthritis can have a significant clinical impact, thus the need for early detection and intervention is crucial.
  • The study points out that most research around biomarkers and musculoskeletal conditions has been concentrated on joint diseases. This is likely due to the high prevalence and significant effect of these disorders on a patient’s quality of life.

CT Scans in the study of bone injuries

  • The second part of the article delves into the use of CT scans, specifically in relation to bone health and injury.
  • A computed tomography (CT) scan is a diagnostic imaging procedure that uses a combination of X-rays and computer technology to produce cross-sectional images (often called slices), both horizontally and vertically, of the body.
  • These scans offer a highly detailed view inside the body, allowing for in-depth examination and assessment of bone health. It offers valuable insights into potential injuries or diseases affecting bones, making it a useful tool in the early detection and monitoring of bone-related conditions.

Conclusion

  • The research predominantly examines the potential of these non-invasive methods in aiding early diagnosis and subsequent treatment of musculoskeletal injury, thereby reducing the associated morbidity and improving patient outcomes.
  • Through enhancing the understanding of how biomarkers and CT scans contribute to the detection and monitoring of issues such as joint disorders and bone conditions, healthcare professionals can refine their approach in preventing and treating these prevalent conditions.

Cite This Article

APA
van Weeren PR, Firth EC. (2008). Future tools for early diagnosis and monitoring of musculoskeletal injury: biomarkers and CT. Vet Clin North Am Equine Pract, 24(1), 153-175. https://doi.org/10.1016/j.cveq.2007.11.008

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 24
Issue: 1
Pages: 153-175

Researcher Affiliations

van Weeren, P René
  • Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 114, NL-3584 CM Utrecht, The Netherlands. p.r.vanweeren@vet.uu.nl
Firth, Elwyn C

    MeSH Terms

    • Animals
    • Biomarkers / metabolism
    • Bone and Bones / metabolism
    • Horse Diseases / diagnosis
    • Horses
    • Joint Diseases / diagnosis
    • Joint Diseases / veterinary
    • Musculoskeletal System / injuries
    • Tomography, X-Ray Computed / methods
    • Tomography, X-Ray Computed / veterinary

    Citations

    This article has been cited 2 times.
    1. Panizzi L, Dittmer KE, Vignes M, Doucet JS, Gedye K, Waterland MR, Rogers CW, Sano H, McIlwraith CW, Riley CB. Plasma and Synovial Fluid Cell-Free DNA Concentrations Following Induction of Osteoarthritis in Horses.. Animals (Basel) 2023 Mar 14;13(6).
      doi: 10.3390/ani13061053pubmed: 36978592google scholar: lookup
    2. Panizzi L, Vignes M, Dittmer KE, Waterland MR, Rogers CW, Sano H, McIlwraith CW, Pemberton S, Owen M, Riley CB. Infrared spectroscopy of serum fails to identify early biomarker changes in an equine model of traumatic osteoarthritis.. Osteoarthr Cartil Open 2022 Dec;4(4):100297.
      doi: 10.1016/j.ocarto.2022.100297pubmed: 36474792google scholar: lookup