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Home / Equine Research Bank / PLoS One / Genetic structure and gene flows within horses: a genealogic...
PloS one2013; 8(4); e61544; doi: 10.1371/journal.pone.0061544

Genetic structure and gene flows within horses: a genealogical study at the french population scale.

Abstract: Since horse breeds constitute populations submitted to variable and multiple outcrossing events, we analyzed the genetic structure and gene flows considering horses raised in France. We used genealogical data, with a reference population of 547,620 horses born in France between 2002 and 2011, grouped according to 55 breed origins. On average, individuals had 6.3 equivalent generations known. Considering different population levels, fixation index decreased from an overall species FIT of 1.37%, to an average [Formula: see text] of -0.07% when considering the 55 origins, showing that most horse breeds constitute populations without genetic structure. We illustrate the complexity of gene flows existing among horse breeds, a few populations being closed to foreign influence, most, however, being submitted to various levels of introgression. In particular, Thoroughbred and Arab breeds are largely used as introgression sources, since those two populations explain together 26% of founder origins within the overall horse population. When compared with molecular data, breeds with a small level of coancestry also showed low genetic distance; the gene pool of the breeds was probably impacted by their reproducer exchanges.
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Publication Date: 2013-04-22 PubMed ID: 23630596PubMed Central: PMC3632587DOI: 10.1371/journal.pone.0061544Google Scholar: Lookup
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  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research examined the genetic structure and gene flows within horse populations in France. It found that most horse breeds do not have a fixed genetic structure and there is a complex network of gene flow between breeds.

Research Methodology

  • The researchers used genealogical data from a population of 547,620 horses born in France between 2002 and 2011.
  • The horses were grouped according to 55 different breed origins.
  • The researchers assessed the equivalent generations known for each horse and found an average of 6.3 equivalent generations.

Findings:

  • The study found that the fixation index, a measure of genetic diversity within a population, did vary when looking at different populations and level.
  • Across the species as a whole, there was a fixation index (FIT) of 1.37% suggesting some level of genetic structure.
  • However, when viewing the 55 origins or breed groups, this decreased to an average of -0.07% suggesting a lack of genetic structure within breeds.

Gene Flows Among Horse Breeds

  • The research found a complex pattern of gene flow between horse breeds, with few populations being closed off to foreign influence.
  • Most breeds show varying levels of introgression, which refers to the transfer of genetic information from one species to another following periods of interbreeding.
  • Two breeds, the Thoroughbred and Arab, were identified as primary sources of gene introgression accounting for 26% of founder origins within the total horse population.

Comparison with Molecular Data

  • When compared with molecular data, breeds with low levels of coancestry also showed low genetic distance.
  • This suggests that the gene pool of the breeds was likely influenced by the number of exchanges between breeders.

This research provides a comprehensive analysis of the genetic structure and gene flows within horse breeds in France. The results improve our understanding of the genetic complexity of domestic horse populations, which could inform breeding practices and conservation efforts.

Cite This Article

APA
Pirault P, Danvy S, Verrier E, Leroy G. (2013). Genetic structure and gene flows within horses: a genealogical study at the french population scale. PLoS One, 8(4), e61544. https://doi.org/10.1371/journal.pone.0061544

Publication

PloS one
ISSN: 1932-6203
NlmUniqueID: 101285081
Country: United States
Language: English
Volume: 8
Issue: 4
Pages: e61544
PII: e61544

Researcher Affiliations

Pirault, Pauline
  • AgroParisTech, Unité Mixte de Recherche 1313 Génétique Animale et Biologie Intégrative, Paris, France.
Danvy, Sophy
    Verrier, Etienne
      Leroy, Grégoire

        MeSH Terms

        • Animals
        • Founder Effect
        • France
        • Gene Flow
        • Genetic Variation
        • Genetics, Population
        • Horses / genetics
        • Inbreeding
        • Models, Genetic
        • Pedigree
        • Phylogeny
        • Probability

        Conflict of Interest Statement

        The authors have declared that no competing interests exist.

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        Citations

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        5. Winton CL, McMahon R, Hegarty MJ, McEwan NR, Davies-Morel MCG, Morgan C, Nash DM. Genetic diversity within and between British and Irish breeds: The maternal and paternal history of native ponies.. Ecol Evol 2020 Feb;10(3):1352-1367.
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