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Animals : an open access journal from MDPI2020; 10(12); doi: 10.3390/ani10122231

Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium.

Abstract: Due to the long courtship needed to attain excitation and erection, donkey semen collection can take up to 90 min. ProstaglandinF2α (PGF2α) has been reported to hasten the onset of erection and ejaculation in domesticated mammals, presumably by inducing smooth muscle contractions in the internal genitalia. However, while it has been anecdotally used in donkeys, it has yet to be critically evaluated. This study aimed to compare behavioral and semen parameters in Catalan, Balearic, Amiata, and Miranda jacks treated with the PGF2α analogue cloprostenol sodium immediately prior to exposure to an estrus jenny. Nineteen donkeys were assigned in a crossover design to receive cloprostenol sodium (125µg, i.m.; n = 53 collections) or saline (1 mL, i.m.; n = 53 collections). There were no differences for erection (52/53 vs. 52/53) or ejaculation (52/53 vs. 48/53) for collection attempts assigned to saline or cloprostenol sodium, respectively. Cloprostenol sodium significantly hastened treatment-to-erection and treatment-to-ejaculation times from 12.0 ± 1.6 to 6.0 ± 1.6 min and from 14.0 ± 1.4 to 9.6 ± 1.4 min, respectively. Significant effects of breed and age were observed in behavioral and parameters, but there were no effects of cloprostenol sodium administration on semen parameters. In conclusion, cloprostenol sodium administration immediately prior to semen collection hastened time to collect semen in donkeys with no detrimental effects on semen quality and can be used by practitioners to circumvent long delays in donkey semen collection.
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Publication Date: 2020-11-27 PubMed ID: 33261078PubMed Central: PMC7760598DOI: 10.3390/ani10122231Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study explores the use of a prostaglandin analog, cloprostenol sodium, to hasten the time to ejaculation in donkey jacks, effectively reducing the time taken in semen collection. The research found that the treatment significantly reduced time to erection and ejaculation without affecting the quality of the semen.

Objective and Method of the Research

  • The study aimed to study the effect of cloprostenol sodium, a prostaglandin F2α analog, on the semen collection process in donkey jacks (male donkeys) from different breeds.
  • Prostaglandins are known to speed up the onset of erection and ejaculation in various mammals. However, their effect in donkeys hasn’t been critically analyzed before.
  • Nineteen donkeys were included in this cross-over design research. They were treated with either 125 µg cloprostenol sodium or 1 mL saline before exposure to an estrus donkey female.
  • The study then compared the time taken to erection and ejaculation along with the behavior and semen parameters to assess the treatment’s efficacy.

Findings of the Study

  • The results showed no significant difference in the frequency of erection (52/53) or ejaculation (52/53 vs. 48/53) when comparing the cloprostenol sodium group to the saline group.
  • However, cloprostenol sodium significantly cut down the time taken to erection (from 12.0 ± 1.6 to 6.0 ± 1.6 minutes) and ejaculation (from 14.0 ± 1.4 to 9.6 ± 1.4 minutes), effectively reducing the time taken for semen collection.
  • The breed and age of the donkeys played a significant role in affecting behavior and related parameters.
  • There was no negative impact on the quality of semen post cloprostenol sodium treatment, making it a viable solution to prevent long delays in semen collection in donkeys.

Conclusion of the Study

  • The study concluded that using cloprostenol sodium prior to semen collection can significantly reduce the time taken to ejaculation in donkey jacks without adversely impacting the semen quality.
  • It provides a practical solution to avoid long semen collection delays while upholding the quality of the collected semen.

Cite This Article

APA
Panzani D, Quaresma M, Fanelli D, Camillo F, Moroni R, Rota A, Martins-Bessa A, Nóvoa M, Catalán J, Canisso IF, Conte G, Mirò J. (2020). Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium. Animals (Basel), 10(12). https://doi.org/10.3390/ani10122231

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 10
Issue: 12

Researcher Affiliations

Panzani, Duccio
  • Department of Veterinary Clinical Sciences, University of Pisa, via Livornese 1286, San Piero a Grado, 56122 Pisa (PI), Italy.
Quaresma, Miguel
  • Center of Animal and Veterinary Science (CECAV) University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, 5000-801 Vila Real, Portugal.
Fanelli, Diana
  • Department of Veterinary Clinical Sciences, University of Pisa, via Livornese 1286, San Piero a Grado, 56122 Pisa (PI), Italy.
Camillo, Francesco
  • Department of Veterinary Clinical Sciences, University of Pisa, via Livornese 1286, San Piero a Grado, 56122 Pisa (PI), Italy.
Moroni, Rebecca
  • Department of Veterinary Clinical Sciences, University of Pisa, via Livornese 1286, San Piero a Grado, 56122 Pisa (PI), Italy.
Rota, Alessandra
  • Department of Veterinary Clinical Sciences, University of Pisa, via Livornese 1286, San Piero a Grado, 56122 Pisa (PI), Italy.
Martins-Bessa, Ana
  • Center of Animal and Veterinary Science (CECAV) University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, 5000-801 Vila Real, Portugal.
Nóvoa, Miguel
  • Association for the Study and Protection of Donkeys (AEPGA), Largo da Igreja, 5225-011 Atenor, Portugal.
Catalán, Jaime
  • Equine Reproduction Service, Department of Animal Medicine and Surgery, Veterinary Faculty, Autonomous University of Barcelona, E-08193 Bellaterra, Cerdanyola del Valles, Spain.
Canisso, Igor F
  • Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, IL 61802, USA.
Conte, Giuseppe
  • Department of Agriculture, Food and Environment, University of Pisa, via del Borghetto 80, 56124 Pisa, Italy.
Mirò, Jordi
  • Equine Reproduction Service, Department of Animal Medicine and Surgery, Veterinary Faculty, Autonomous University of Barcelona, E-08193 Bellaterra, Cerdanyola del Valles, Spain.

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

This article has been cited 2 times.
  1. Martins-Bessa A, McLean AK. Advances in Donkey and Mule Research. Animals (Basel) 2024 Aug 1;14(15).
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  2. Khanam A, Swelum AA, Khan FA. Pharmacologically Induced Ex Copula Ejaculation in Horses and Donkeys. Front Vet Sci 2021;8:669423.
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