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Veterinary parasitology2008; 154(3-4); 233-241; doi: 10.1016/j.vetpar.2008.02.034

Health management of horses under high challenge from trypanosomes: a case study from Serengeti, Tanzania.

Abstract: Horses kept for recreational riding purposes by a wildlife tourism company in a heavily tsetse fly-infested region of north-western Tanzania were systematically monitored to investigate the occurrence, presentation and management of tsetse-transmitted trypanosomosis. During a 23-month period, 18 clinical cases were diagnosed (Trypanosoma brucei or Trypanosoma congolense were identified) and treated and trypanosomes were implicated of involvement in four deaths. Pyrexia consistently aided early detection (17 cases). Ataxia, weight loss and anaemia were seen in chronic cases and conferred a poor prognosis. Delaying treatment by more than 2 days from the onset of clinical signs led to prolonged disease course and more severe anaemia. Early detection, prompt treatment, thorough post-treatment health monitoring and rigorous prophylactic measures helped keep clinical cases to manageable levels, but re-infection remained a constant, insidious threat.
Publication Date: 2008-03-14 PubMed ID: 18450381DOI: 10.1016/j.vetpar.2008.02.034Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research paper revolves around the study of horses used for recreational purposes in Tanzania by a wildlife company, in an area heavily infested with Tsetse flies. The aim is to understand the occurrence, symptoms and management of diseases transmitted by these flies to the horses. The focus is on early detection and prompt treatment of these diseases to avoid severe implications or deaths.

Study Overview

  • The research was conducted over a 23-month period.
  • During this time, the horses were systematically observed to understand the impact of diseases, primarily Trypanosomosis, transmitted by Tsetse flies.
  • Out of the total cases observed, 18 were diagnosed with Trypanosoma brucei or Trypanosoma congolense and were given appropriate treatment.

Symptoms & Diagnosis

  • The horses showed various symptoms like fever, ataxia (loss of control over body movements), weight loss and anaemia.
  • An early red flag that helped in detecting the disease was constant fever in 17 out of 18 clinical cases.
  • More chronic symptoms were loss of weight, anemia, and ataxia. It was inferred that their presence meant a poor prognosis, indicating a more severe disease situation.
  • Delay in treatment, particularly more than two days after the onset of these clinical symptoms, led to a more prolonged recovery period and heightened severity of anaemia.

Management & Prevention

  • Early detection and prompt administration of treatment were crucial in the disease management process.
  • Rigorous post-treatment health monitoring was also enforced to keep a check on any lingering effects of the disease or its recurrence.
  • Additionally, thorough prophylactic measures were undertaken to prevent future instances of the disease.
  • However, despite these efforts, re-infection from the flies posed a persistent, stealthy threat.

Conclusions

  • Even with early detection and prompt treatment, re-infection remained a significant issue, indicating the need for more effective preventive measures.
  • The study suggested the necessity of constant vigilance in high-risk regions to control disease impact.
  • Though the measures taken helped to manage the disease to an extent, the threat of trypanosomosis in such regions remains a pressing concern for animal health.

Cite This Article

APA
Auty H, Mundy A, Fyumagwa RD, Picozzi K, Welburn S, Hoare R. (2008). Health management of horses under high challenge from trypanosomes: a case study from Serengeti, Tanzania. Vet Parasitol, 154(3-4), 233-241. https://doi.org/10.1016/j.vetpar.2008.02.034

Publication

ISSN: 0304-4017
NlmUniqueID: 7602745
Country: Netherlands
Language: English
Volume: 154
Issue: 3-4
Pages: 233-241

Researcher Affiliations

Auty, Harriet
  • Centre for Tropical Veterinary Medicine, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian EH25 9RG, UK. h.k.auty@sms.ed.ac.uk
Mundy, Alison
    Fyumagwa, Robert D
      Picozzi, Kim
        Welburn, Susan
          Hoare, Richard

            MeSH Terms

            • Animal Husbandry
            • Animals
            • Horse Diseases / drug therapy
            • Horse Diseases / epidemiology
            • Horse Diseases / prevention & control
            • Horses
            • Phenanthridines / therapeutic use
            • Quinolinium Compounds / therapeutic use
            • Tanzania / epidemiology
            • Trypanocidal Agents / therapeutic use
            • Trypanosomiasis, African / drug therapy
            • Trypanosomiasis, African / epidemiology
            • Trypanosomiasis, African / prevention & control
            • Trypanosomiasis, African / veterinary

            Citations

            This article has been cited 7 times.
            1. Gummery L, Jallow S, Raftery AG, Bennet E, Rodgers J, Sutton DGM. Comparison of loop-mediated isothermal amplification (LAMP) and PCR for the diagnosis of infection with Trypanosoma brucei ssp. in equids in The Gambia.. PLoS One 2020;15(8):e0237187.
              doi: 10.1371/journal.pone.0237187pubmed: 32833981google scholar: lookup
            2. Raftery AG, Jallow S, Coultous RM, Rodgers J, Sutton DGM. Variation in disease phenotype is marked in equine trypanosomiasis.. Parasit Vectors 2020 Mar 21;13(1):148.
              doi: 10.1186/s13071-020-04020-6pubmed: 32199454google scholar: lookup
            3. Büscher P, Gonzatti MI, Hébert L, Inoue N, Pascucci I, Schnaufer A, Suganuma K, Touratier L, Van Reet N. Equine trypanosomosis: enigmas and diagnostic challenges.. Parasit Vectors 2019 May 15;12(1):234.
              doi: 10.1186/s13071-019-3484-xpubmed: 31092285google scholar: lookup
            4. Raftery AG, Jallow S, Rodgers J, Sutton DGM. Safety and efficacy of three trypanocides in confirmed field cases of trypanosomiasis in working equines in The Gambia: a prospective, randomised, non-inferiority trial.. PLoS Negl Trop Dis 2019 Mar;13(3):e0007175.
              doi: 10.1371/journal.pntd.0007175pubmed: 30901321google scholar: lookup
            5. Giordani F, Morrison LJ, Rowan TG, DE Koning HP, Barrett MP. The animal trypanosomiases and their chemotherapy: a review.. Parasitology 2016 Dec;143(14):1862-1889.
              doi: 10.1017/S0031182016001268pubmed: 27719692google scholar: lookup
            6. Onmaz AC, Beutel RG, Schneeberg K, Pavaloiu AN, Komarek A, van den Hoven R. Vectors and vector-borne diseases of horses.. Vet Res Commun 2013 Mar;37(1):65-81.
              doi: 10.1007/s11259-012-9537-7pubmed: 23054414google scholar: lookup
            7. Da Silva AS, Garcia Perez HA, Costa MM, França RT, De Gasperi D, Zanette RA, Amado JA, Lopes ST, Teixeira MM, Monteiro SG. Horses naturally infected by Trypanosoma vivax in southern Brazil.. Parasitol Res 2011 Jan;108(1):23-30.
              doi: 10.1007/s00436-010-2036-2pubmed: 20820805google scholar: lookup