Hematology and biochemistry reference values for the light horse.
Abstract: Reference hematology and biochemistry intervals are presented for a number of variables of clinical interest determined for blood samples obtained from 60 thoroughbred mares, 12 thoroughbred foals and 50 standardbred horses in training. The observations for each variable were examined for outliers and Gaussian distribution. Parametric analysis was used where the observations were Gaussian initially or after any of four transformations, otherwise nonparametric analysis was required for estimation of the 2.5 and 97.5 percentiles. Description of the sample collection procedures, laboratory methods and statistical analysis are available allowing comparison and judicious application of these reference intervals by interested researchers and clinicians.
Publication Date: 1980-01-01 PubMed ID: 7397597PubMed Central: PMC1320032
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- Comparative Study
- Journal Article
Summary
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The research paper presents established biochemistry and hematology reference values for different variables of clinical interest in blood samples from various classes of horses, including thoroughbred mares, foals, and horses in training. These references serve as beneficial tools for researchers and clinicians for comparison and suitable application.
Collection of Blood Samples and Selection of Variables
- The study drew blood samples from a varied selection of horses, 60 thoroughbred mares, 12 foals and 50 actively training standardbred horses.
- These samples were then examined for several clinical variables of interest to establish the reference values. However, the specific variables looked into are not stated in the abstract. It is necessary to read the complete research paper to understand what these variables were.
Analysis and Estimation
- The values for each of these clinical variables were analyzed for outliers and Gaussian distribution, which is a standard statistical method used to understand how the data is distributed.
- Where the distribution was Gaussian (or after alterations), parametric analysis was implemented. Parametric statistical methods make certain assumptions about the variables and are commonly used when the data follow a certain distribution.
- If the values were not following a Gaussian distribution initially or after alterations, nonparametric analysis was adopted. The nonparametric method doesn’t make assumptions based on a specific distribution and was used to estimate the 2.5% and 97.5% percentiles. These percentiles are used to establish a reference range. Any value that falls outside of this range might be considered abnormal or warrant further investigation.
Implications and Usage
- The reference intervals provided are not meant to replace individual clinic’s reference intervals, but rather to be used by researchers and clinicians to compare and adapt properly into their specific situation.
- The process and methods used for sample collection, lab work, and statistical analysis are accessible for review. This transparency allows for accurate comparisons and sensible application of the reference values by interested parties.
Cite This Article
APA
Lumsden JH, Rowe R, Mullen K.
(1980).
Hematology and biochemistry reference values for the light horse.
Can J Comp Med, 44(1), 32-42.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Female
- Horses / blood
- Male
- Reference Values
References
This article includes 19 references
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Citations
This article has been cited 10 times.- Wensley FM, Berryhill EH, Magdesian KG. Association of globulin concentrations with prognosis in horses with lymphoma.. Front Vet Sci 2022;9:1086010.
- Morón-Elorza P, Rojo-Solis C, Steyrer C, Álvaro-Álvarez T, Valls-Torres M, Encinas T, García-Párraga D. Hematology and Plasma Chemistry Reference Values in Nursehound Shark (Scyliorhinus Stellaris) Maintained Under Human Care.. Front Vet Sci 2022;9:909834.
- Kinsella HM, Hostnik LD, Snyder HA, Mazur SE, Kamr AM, Burns TA, Mossbarger JC, Toribio RE. Comparison of insulin sensitivity between healthy neonatal foals and horses using minimal model analysis.. PLoS One 2022;17(1):e0262584.
- Farrell A, Kersh K, Liepman R, Dembek KA. Development of a Colic Scoring System to Predict Outcome in Horses.. Front Vet Sci 2021;8:697589.
- Du X, Liu X, Mawolo JB, Wang H, Mi X, Dong J, Li Q, Wen Y. Determination of haematological and biochemical parameters of Calf Saiga antelope (Saiga tatarica) living in the Gansu Endangered Animals Research Center.. Vet Med Sci 2020 Aug;6(3):591-599.
- Liu X, Mawolo JB, Du X, Zhou Y, Wang H, Liu F, He Z, Marela HA. Investigation of biochemical and physiological parameters of the newborn Saiga antelope (Saiga tatarica) in Gansu Province, China.. PLoS One 2019;14(11):e0224822.
- Ono T, Yamada Y, Hata A, Shimokawa Miyama T, Shibano K, Iwata E, Ohzawa E, Kitagawa H. Reference values of hematological and blood biochemical parameters for the Noma horse.. J Equine Sci 2019 Sep;30(3):69-73.
- Leidinger EF, Leidinger J, Figl J, Rumpler B, Schwendenwein I. Application of the ASVCP guidelines for the establishment of haematologic and biochemical reference intervals in Icelandic horses in Austria.. Acta Vet Scand 2015 Jun 14;57(1):30.
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- Pascoe PJ, Ducharme NG, Ducharme GR, Lumsden JH. A computer-derived protocol using recursive partitioning to aid in estimating prognosis of horses with abdominal pain in referral hospitals.. Can J Vet Res 1990 Jun;54(3):373-8.
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