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Histologic features of the carotid artery trifurcation in thoroughbreds.

Abstract: The common, external, and internal carotid and occipital arteries were examined histologically at the trifurcation of the common carotid arteries in 13 Thoroughbred foals (0 to 30 days old) and 64 Thoroughbred adults (2 to 4 years old). Calcification in the media of the common carotid and external carotid arteries was observed in 3 of the 13 foals and in 30 of the 64 adult horses. Calcification resembled that seen in Mönckeberg's arteriosclerosis in human beings, the cause of which is unknown.
Publication Date: 1992-03-01 PubMed ID: 1595952
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  • Journal Article

Summary

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The research article looks at the structural features of the area where the common carotid artery branches in young and adult Thoroughbred horses. It identifies calcification, similar to a type of hardening of the arteries seen in human beings, present in both age groups.

Research Context and Purpose

  • The study was conducted in the context of understanding the histological (study of the microscopic anatomy of cells and tissues) features of the carotid artery trifurcation (the point where the common carotid artery divides) in Thoroughbred horses.
  • The primary aim was to investigate the presence of calcification (hardening due to calcium deposits) in the arteries of these horses.

Sample and Method

  • The research was carried out on 13 newly born (0 to 30 days old) Thoroughbred foals and 64 adult Thoroughbred horses (2 to 4 years old).
  • The common, external, and internal carotid and occipital arteries at the point of trifurcation of the common carotid arteries in these horses were examined histologically, meaning tissue samples were analyzed under a microscope.

Findings of the Study

  • Calcification in the media (middle layer) of the common and external carotid arteries was observed in 3 of the 13 foals and 30 of the 64 adults. This implies that both young and grown horses can experience hardening of these arteries due to calcium deposits.
  • The calcification observed in these horses showed similarities to Mönckeberg’s arteriosclerosis, a medical condition seen in humans characterized by calcification of the middle layer of the arteries. This disease’s origin remains unknown in medicine, indicating that the cause of the equivalent calcification in horses is also unclear.

Cite This Article

APA
Nakamura T, Kiryu K, Machida N, Iwata T, Oikawa M, Kaneko M. (1992). Histologic features of the carotid artery trifurcation in thoroughbreds. Am J Vet Res, 53(3), 288-290.

Publication

ISSN: 0002-9645
NlmUniqueID: 0375011
Country: United States
Language: English
Volume: 53
Issue: 3
Pages: 288-290

Researcher Affiliations

Nakamura, T
  • Department of Veterinary Pathology, Tokyo University of Agriculture and Technology, Japan.
Kiryu, K
    Machida, N
      Iwata, T
        Oikawa, M
          Kaneko, M

            MeSH Terms

            • Animals
            • Calcinosis / pathology
            • Calcinosis / veterinary
            • Carotid Arteries / pathology
            • Carotid Artery Diseases / pathology
            • Carotid Artery Diseases / veterinary
            • Edema
            • Horse Diseases / pathology
            • Horses
            • Muscle, Smooth, Vascular / pathology

            Citations

            This article has been cited 2 times.
            1. Tsang HG, Rashdan NA, Whitelaw CB, Corcoran BM, Summers KM, MacRae VE. Large animal models of cardiovascular disease. Cell Biochem Funct 2016 Apr;34(3):113-32.
              doi: 10.1002/cbf.3173pubmed: 26914991google scholar: lookup
            2. Maeda Y, Kanno C, Sugiyama M, Yamamoto R, Sato S, Ando R, Noda R, Kawaguchi H, Takahashi F. Sudden death in a Thoroughbred stallion: cardiac tamponade due to transverse aortic rupture with bone metaplasia and calcification. J Equine Sci 2025 Jun;36(2):75-79.
              doi: 10.1294/jes.36.75pubmed: 40832001google scholar: lookup