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Equine veterinary journal2006; 38(1); 47-51; doi: 10.2746/042516406775374207

Horses on pasture may be affected by equine motor neuron disease.

Abstract: Equine motor neuron disease (EMND) was diagnosed in 3 horses maintained on lush, grass-based pasture. This contrasted with North American studies which identified limited or no access to green herbage as an important risk factor for EMND. Objective: Grazing horses that have an apparently adequate intake of pasture herbage to meet normal equine vitamin E requirements can develop EMND. Methods: Owners of 32 European horses diagnosed with EMND completed a questionnaire regarding intrinsic, managemental, nutritional and environmental factors that could potentially be risk factors for EMND, and also regarding clinical signs, treatments and case outcome. Plasma/serum vitamin E data for these horses were supplied by the veterinarians. No control population was studied. Results: Thirteen of 32 horses (termed the 'grazing' group) had part- or full-time access to grass-based pasture at the onset of EMND (median duration at pasture 12 h/day, range 3-24 h). Five of these horses were at pasture for at least 235 h/day at the onset of EMND, 2 of which were at pasture for at least 23.5 h/day throughout the year. Despite grazing, all these horses had a low vitamin E status. The remaining 19 horses resembled those cases reported from North America, in that they had no or limited access to pasture. Conclusions: A diagnosis of EMND should not be discounted on the basis that a horse has access, even full-time, to lush grass-based pasture. Inadequate vitamin E intake was probably not the sole cause of either the EMND or the low vitamin E status in the grazing horses; the latter was probably the result of abnormal bioavailability or excessive utilisation of vitamin E.
Publication Date: 2006-01-18 PubMed ID: 16411586DOI: 10.2746/042516406775374207Google Scholar: Lookup
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  • Journal Article

Summary

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The research article focuses on equine motor neuron disease (EMND) found in three horses that were fed on lush, grass-based pasture, an occurrence contrasting from North American findings where a lack of or limited access to green herbage is identified as a major risk factor for EMND.

Objective and Methods

  • The primary objective of this research was to investigate if horses that are getting a seemingly sufficient intake of pasture herbage, which should meet their normal vitamin E requirements, can still develop EMND.
  • The research methodology involved a questionnaire filled out by the owners of 32 European horses, all of which were diagnosed with EMND. The questionnaire inquired about various potential risk factors for EMND, which included factors intrinsic to the horses, management-related factors, nutritional factors, and environmental factors. It also sought information about symptoms, treatments, and the outcomes of each case.
  • Along with the questionnaire, serum/plasma vitamin E data for these horses were also supplied by the veterinarians. It’s important to note that no control group was used in this study.

Results

  • The results of the study showed that thirteen out of the 32 horses, or the ‘grazing’ group, had part-time or full-time access to grass-based pasture when EMND was first noticed. More specifically, some horses were grazing for at least 235 hours per day at the onset of EMND. Interestingly, despite grazing, the vitamin E status of all these horses was low.
  • The remaining 19 horses were matched to cases reported in North America where the horses had limited or no access to green herbage.

Conclusions

  • The study concludes that EMND cannot be dismissed just because a horse has access, even full-time, to lush, grass-based pasture.
  • Furthermore, it suggests that insufficient vitamin E intake was unlikely the sole cause for either the low vitamin E status or the occurrence of EMND in the grazing horses. The researchers theorize that this might be due to aberrant bioavailability or exaggerated utilisation of vitamin E.

Cite This Article

APA
McGorum BC, Mayhew IG, Amory H, Deprez P, Gillies L, Green K, Mair TS, Nollet H, Wijnberg ID, Hahn CN. (2006). Horses on pasture may be affected by equine motor neuron disease. Equine Vet J, 38(1), 47-51. https://doi.org/10.2746/042516406775374207

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 38
Issue: 1
Pages: 47-51

Researcher Affiliations

McGorum, B C
  • Department of Veterinary Clinical Studies, University of Edinburgh, Easter Bush Veterinary Centre, Easter Bush, Roslin, Midlothian EH25 9RG, UK.
Mayhew, I G
    Amory, H
      Deprez, P
        Gillies, L
          Green, K
            Mair, T S
              Nollet, H
                Wijnberg, I D
                  Hahn, C N

                    MeSH Terms

                    • Animal Feed
                    • Animal Nutritional Physiological Phenomena
                    • Animals
                    • Biological Availability
                    • Breeding
                    • Environment
                    • Female
                    • Horse Diseases / blood
                    • Horse Diseases / etiology
                    • Horses
                    • Male
                    • Motor Neuron Disease / blood
                    • Motor Neuron Disease / etiology
                    • Motor Neuron Disease / veterinary
                    • Nutritional Requirements
                    • Nutritional Status
                    • Poaceae
                    • Risk Factors
                    • Surveys and Questionnaires
                    • Vitamin E / administration & dosage
                    • Vitamin E / blood
                    • Vitamin E Deficiency / blood
                    • Vitamin E Deficiency / complications
                    • Vitamin E Deficiency / veterinary
                    • Vitamins / administration & dosage
                    • Vitamins / blood

                    Citations

                    This article has been cited 5 times.
                    1. Żak A, Siwińska N, Chełmecka E, Bażanów B, Romuk E, Adams A, Niedźwiedź A, Stygar D. Effects of Advanced Age, Pituitary Pars Intermedia Dysfunction and Insulin Dysregulation on Serum Antioxidant Markers in Horses. Antioxidants (Basel) 2020 May 21;9(5).
                      doi: 10.3390/antiox9050444pubmed: 32455574google scholar: lookup
                    2. Díez de Castro E, Zafra R, Acevedo LM, Pérez J, Acosta I, Rivero JL, Aguilera-Tejero E. Eosinophilic Enteritis in Horses with Motor Neuron Disease. J Vet Intern Med 2016 May;30(3):873-9.
                      doi: 10.1111/jvim.13944pubmed: 27015868google scholar: lookup
                    3. McGorum BC, Pirie RS, Glendinning L, McLachlan G, Metcalf JS, Banack SA, Cox PA, Codd GA. Grazing livestock are exposed to terrestrial cyanobacteria. Vet Res 2015 Feb 25;46:16.
                      doi: 10.1186/s13567-015-0143-xpubmed: 25828258google scholar: lookup
                    4. Delguste C, de Moffarts B, Kirschvink N, Art T, Pincemail J, Defraigne JO, Amory H, Lekeux P. Change in blood antioxidant status of horses moved from a stable following diagnosis of equine motor neuron disease. Can Vet J 2007 Nov;48(11):1165-7.
                      pubmed: 18050798
                    5. Mohammed HO, Divers TJ, Summers BA, de Lahunta A. Vitamin E deficiency and risk of equine motor neuron disease. Acta Vet Scand 2007 Jul 2;49(1):17.
                      doi: 10.1186/1751-0147-49-17pubmed: 17605810google scholar: lookup