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Home / Equine Research Bank / Can Vet J / Hypertrophic osteopathy secondary to metastatic ovarian aden...
The Canadian veterinary journal = La revue veterinaire canadienne2016; 57(12); 1237-1241;

Hypertrophic osteopathy secondary to metastatic ovarian adenocarcinoma in a mare.

Abstract: A 10-year-old Andalusian mare was presented for evaluation of weight loss, increasing periods of recumbency, and swelling of the lower limbs. Radiographs revealed severe palisading to solid periosteal new bone formation in numerous locations. Necropsy revealed a metastatic malignant adenocarcinoma of ovarian origin with secondary hypertrophic osteopathy. Une jument d’Andalousie âgée de 10 ans a été présentée pour évaluation à la suite d’une perte de poids, de périodes croissantes de décubitus et d’enflure dans les membres inférieurs. Les radiographies ont révélé des lésions allant d’une disposition en palissades sévère jusqu’à la formation de nouvel os périostique solide à plusieurs endroits. La nécropsie a révélé un adénocarcinome malin métastatique d’origine ovarienne avec une ostéopathie hypertrophique secondaire.(Traduit par Isabelle Vallières).
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Publication Date: 2016-12-09 PubMed ID: 27928168PubMed Central: PMC5109623
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study investigates a case where a 10-year-old Andalusian mare showed signs of weight loss, prolonged periods of lying down, and swelling in the lower limbs due to a malignant ovarian tumor that led to a rare secondary disease known as hypertrophic osteopathy.

Introduction to the Case

  • The research revolves around a unique case where a 10-year-old Andalusian mare exhibited signs of weight loss, increasing periods of recumbency (lying down), and swelling in the lower limbs.
  • The case builds interest because these symptoms resulted from a secondary, rarer disease known as hypertrophic osteopathy. This disease appeared due to a primary condition— a metastatic malignant ovarian tumor called adenocarcinoma.

Radiographic Examination

  • Radiographs taken of the mare revealed an increased formation of new bone in numerous locations, which is a typical sign of hypertrophic osteopathy.
  • These formations ranged from severe palisading (characterized by a radiographic pattern of lines perpendicular to the bone’s surface) to a solid formation of bone (periosteal new bone).

Necropsy Findings

  • The severity of the mare’s condition was fully realized upon performing a necropsy, where researchers discovered the presence of a metastatic malignant adenocarcinoma of ovarian origin. This type of cancer typically starts in the tissue that lines certain internal organs like the ovaries.
  • The metastatic nature of the ovarian tumor meant that the cancer had spread from its original site (ovaries) to other parts of the body, leading to the secondary development of hypertrophic osteopathy.
  • Hypertrophic osteopathy is characterized by increased bone density and volume, mainly affecting the long bones. In this case, the condition resulted in symptoms like limb swelling and extended periods of the mare lying down. It also led to overall weight loss in the mare.

Cite This Article

APA
Browne NS, Scarratt WK, Robertson J. (2016). Hypertrophic osteopathy secondary to metastatic ovarian adenocarcinoma in a mare. Can Vet J, 57(12), 1237-1241.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 57
Issue: 12
Pages: 1237-1241

Researcher Affiliations

Browne, Nimet S
  • Virginia - Maryland Regional College of Veterinary Medicine, Phase 2, Duckpond Drive, Blacksburg, Virginia 24060, USA.
Scarratt, William K
  • Virginia - Maryland Regional College of Veterinary Medicine, Phase 2, Duckpond Drive, Blacksburg, Virginia 24060, USA.
Robertson, John
  • Virginia - Maryland Regional College of Veterinary Medicine, Phase 2, Duckpond Drive, Blacksburg, Virginia 24060, USA.

MeSH Terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / veterinary
  • Animals
  • Female
  • Horse Diseases / diagnosis
  • Horse Diseases / etiology
  • Horse Diseases / pathology
  • Horses
  • Hyperostosis / etiology
  • Hyperostosis / veterinary
  • Ovarian Neoplasms / complications
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / veterinary

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Citations

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