Impact of Size and Shape of Equine Femoral Subchondral Bone Cysts With a Transcondylar Screw on Predicted Bone Formation Area in a Finite Element Model.
Abstract: Equine subchondral bone cysts (SBCs) develop most often in the medial femoral condyle (MFC) of yearlings intended for performance. SBCs often cause lameness and can cause secondary injuries to the meniscus and tibial cartilage. A novel surgical technique using a transcondylar lag screw (TLS) across an MFC SBC has shown success in lameness resolution and radiographic healing of MFC SBC. In a previous study using finite element analysis, our lab showed that a TLS stimulated bone formation on the inner surface of the SBC and altered third principal stress vectors to change the direction of surface compression to align with the screw axis. This work extended the previous study, which was limited by the use of only one idealized SBC. Our objective was to test SBCs of several sizes and shapes in a newly developed equine stifle FEM with a TLS to determine how cyst size affects bone formation stimulation. This study found that a transcondylar screw is most effective in stimulating bone formation in cysts of greater height (proximal-distal). The TLS increases stress stimulus in the bone around the cyst to promote bone apposition and directs compression across the cyst. If full penetration of the screw through the cyst is possible, it is recommended that the transcondylar screw be used to treat subchondral bone cysts. For the treatment of smaller cysts that are not accessible by the current screw surgical approach, future work could study the efficacy of a dual-pitch headless screw that may reach smaller cysts.
Copyright © 2020 by ASME.
Publication Date: 2020-01-05 PubMed ID: 31901159DOI: 10.1115/1.4045892Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The research investigates the influence of the size and shape of horse femoral subchondral bone cysts on the effectiveness of a surgical treatment involving a transcondylar screw. The research finds that larger cysts, particularly those of greater height, respond best to this treatment method.
Introduction to Equine Subchondral Bone Cysts and Their Treatment
- Subchondral bone cysts (SBCs) are a common problem in horses, particularly yearlings intended for performance. They usually develop in the medial femoral condyle (MFC) and often cause lameness and secondary injuries to the meniscus and tibial cartilage.
- A surgical technique involving the insertion of a transcondylar lag screw (TLS) across an affected MFC has been shown to be successful in resolving lameness and promoting healing of the SBC.
- This is because, as shown through finite element analysis in a previous study, the TLS stimulates bone formation on the inner surface of the SBC, and changes the direction of surface compression to align with the screw axis.
Objective and Methodology of the Study
- This research extends the previous finite element analysis by testing several sizes and shapes of SBCs in a new equine stifle finite element model (FEM).
- The goal was to determine how the size of the cyst impacts the ability of the TLS to stimulate bone formation.
Key Findings of the Research
- The research found that a transcondylar screw works best in stimulating bone formation in cysts of greater height, and increases stress stimulus in the bone around the cyst, promoting bone apposition (the addition of new bone).
- The screw also directs compression across the cyst, which aids in healing. If the screw can fully penetrate the cyst, its use is recommended for treating SBCs.
Future Research Recommendations
- The researchers acknowledge that their findings apply best to larger cysts that can be accessed by a TLS. Smaller cysts that can’t be accessed by the current screw surgical approach remain a challenge.
- Future research could study the efficacy of a dual-pitch headless screw, which may be able to reach and treat smaller cysts effectively.
Cite This Article
APA
Frazer LL, Santschi EM, Ring SJ, Hewitt RE, Fischer KJ.
(2020).
Impact of Size and Shape of Equine Femoral Subchondral Bone Cysts With a Transcondylar Screw on Predicted Bone Formation Area in a Finite Element Model.
J Biomech Eng, 142(6), 061010.
https://doi.org/10.1115/1.4045892 Publication
Researcher Affiliations
- Bioengineering Program, University of Kansas, Lawrence, KS 66045.
- College of Veterinary Medicine, Kansas State University, Manhattan, KS 66502.
- Department of Mechanical Engineering, University of Kansas, Lawrence, KS 66045.
- School of Management, University of Missouri-Kansas City, Kansas City, MO 64110.
- Department of Mechanical Engineering, University of Kansas, Lawrence, KS 66045; Bioengineering Program, University of Kansas, Lawrence, KS 66045.
MeSH Terms
- Animals
- Bone Cysts
- Bone Screws
- Femur
- Finite Element Analysis
- Horses
- Osteogenesis
- Tibia
Citations
This article has been cited 4 times.- Hamsayeh Abbasi Niasar E, Li L. Implication of region-dependent material properties of articular cartilage in the contact mechanics of porcine knee joint. BMC Musculoskelet Disord 2025 Feb 14;26(1):149.
- Pérez-Nogués M, Manso-Díaz G, Spirito M, López-Sanromán J. Treatment Comparison for Medial Femoral Condyle Subchondral Cystic Lesions and Prognosis in Yearling Thoroughbred Racehorse Prospects. Animals (Basel) 2024 Apr 6;14(7).
- Canonici F, Marcoccia D, Bonini P, Monteleone V, Innocenzi E, Zepparoni A, Altigeri A, Caciolo D, Tofani S, Ghisellini P, Rando C, Pechkova E, Rau JV, Eggenhöffner R, Scicluna MT, Barbaro K. Arthroscopic Treatment of a Subchondral Bone Cyst via Stem Cells Application: A Case Study in Equine Model and Outcomes. Biomedicines 2023 Dec 14;11(12).
- Pérez-Nogués M, López-Sanromán J, Spirito M, Manso-Díaz G. Treatments and Prognosis for Subchondral Cystic Lesions in the Distal Extremities in Thoroughbred Prospect Racehorses. Animals (Basel) 2023 Sep 7;13(18).
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