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The Veterinary clinics of North America. Equine practice2023; 39(1); 73-88; doi: 10.1016/j.cveq.2022.11.001

Infectious Causes of Equine Placentitis and Abortion.

Abstract: A variety of infectious agents including viral, bacterial, and fungal organisms can cause equine abortion and placentitis. Knowledge of normal anatomy and the common pattern distribution of different infectious agents will assist the practitioner in evaluating the fetus and/or placenta, collecting appropriate samples for further testing, and in some cases, forming a presumptive diagnosis. In all cases, it is recommended to confirm the diagnosis with molecular, serologic, or microbiological testing. If a causative agent can be identified, then appropriate biosecurity and vaccination measures can be instituted on the farm.
Publication Date: 2023-02-01 PubMed ID: 36737287DOI: 10.1016/j.cveq.2022.11.001Google Scholar: Lookup
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Summary

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The research investigates different infectious agents as causes for horse miscarriages and placentitis, and how recognizing the typical distribution patterns of these agents can aid in forming presumptive diagnoses, which should be confirmed with further testing. The study also emphasizes the implementation of suitable biosecurity and vaccination procedures if a causative agent is identified.

Understanding the Infectious Agents

  • The research focuses on various infectious agents including those of viral, bacterial, and fungal nature, all of which can lead to equine abortion and placentitis (inflammation of the placenta in horses).
  • Identifying the cause is essential because it enables the appropriate response, from treatment to preventing the spread of infection. Depending on the agent identified, it can define the biosecurity measures and the kind of vaccines that should be used on the farm.

The Significance of Normal Anatomy and Pattern Distribution

  • Knowledge of regular equine anatomy and how different infectious agents are commonly distributed is vital for practitioners. This understanding aids in evaluating the fetus and/or placenta competently, and enables practitioners to assume a presumptive diagnosis based on the prevalent pattern of infection.
  • These preliminary analyses, although very valuable, are not conclusive on their own. Therefore, the study emphasizes the necessity of additional testing to confirm the presumptive diagnosis.

The Importance of Confirming the Diagnosis

  • Regardless of the presumptions made based on the observed patterns, the research stresses the importance of confirming these with further molecular, serologic, or microbiological testing. This step ensures an accurate diagnosis and positive identification of the causative agent.
  • Understanding the exact cause is critical for determining the correct response and treatment methods, thus preventing possibly ineffective treatments and unnecessary resources expenditure.

Promoting Prevention and Biosecurity Measures

  • Once the causative agent of a disease is accurately identified, adequate biosecurity measures can be implemented to limit the disease’s spread on the farm.
  • Effective biosecurity measures can result in significant economic savings by reducing morbidity and mortality rates, and preventing future outbreak incidents. Furthermore, if known, appropriate vaccination regimes can be instituted among the equine population.

Cite This Article

APA
Ruby RE, Janes JG. (2023). Infectious Causes of Equine Placentitis and Abortion. Vet Clin North Am Equine Pract, 39(1), 73-88. https://doi.org/10.1016/j.cveq.2022.11.001

Publication

ISSN: 1558-4224
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 39
Issue: 1
Pages: 73-88
PII: S0749-0739(22)00065-7

Researcher Affiliations

Ruby, Rebecca E
  • Department of Veterinary Science, University of Kentucky, Veterinary Diagnostic Laboratory, 1490 Bull Lea Road, Lexington, KY 40511, USA. Electronic address: rebecca.ruby@uky.edu.
Janes, Jennifer G
  • Department of Veterinary Science, University of Kentucky, Veterinary Diagnostic Laboratory, 1490 Bull Lea Road, Lexington, KY 40511, USA.

MeSH Terms

  • Pregnancy
  • Female
  • Animals
  • Horses
  • Placenta Diseases / microbiology
  • Placenta Diseases / veterinary
  • Abortion, Veterinary / microbiology
  • Horse Diseases / etiology
  • Placenta / microbiology

Citations

This article has been cited 3 times.
  1. Wang Z, Zeng S, Wang Y, Wang T, Qu H, Zhu Y, Li J. Reproductive Disorders in Donkeys: Current Evidence and Update. Animals (Basel) 2024 Aug 28;14(17).
    doi: 10.3390/ani14172494pubmed: 39272279google scholar: lookup
  2. Li L, Li S, Ma H, Akhtar MF, Tan Y, Wang T, Liu W, Khan A, Khan MZ, Wang C. An Overview of Infectious and Non-Infectious Causes of Pregnancy Losses in Equine. Animals (Basel) 2024 Jul 2;14(13).
    doi: 10.3390/ani14131961pubmed: 38998073google scholar: lookup
  3. Mai Z, Fu H, Miao R, Lu C, Zhang X, Yuan Z, Ji P, Hua Y, Wang C, Ma Y, Deng H, Wei Y. Serological investigation and isolation of Salmonella abortus equi in horses in Xinjiang. BMC Vet Res 2024 Mar 15;20(1):103.
    doi: 10.1186/s12917-024-03955-7pubmed: 38491518google scholar: lookup