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Emerging infectious diseases2011; 17(10); 1883-1886; doi: 10.3201/eid1710.110350

Isolation and phylogenetic grouping of equine encephalosis virus in Israel.

Abstract: During 2008-2009 in Israel, equine encephalosis virus (EEV) caused febrile outbreaks in horses. Phylogenetic analysis of segment 10 of the virus strains showed that they form a new cluster; analysis of segment 2 showed ≈92% sequence identity to EEV-3, the reference isolate. Thus, the source of this emerging EEV remains uncertain.
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Publication Date: 2011-10-18 PubMed ID: 22000361PubMed Central: PMC3310674DOI: 10.3201/eid1710.110350Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article examines the outbreak of the equine encephalosis virus (EEV) in horses in Israel between 2008-2009, highlights the detection and examination of new virus strains, and discusses the phylogenetic analysis establishing these strains as a unique cluster. However, the exact origin of this EEV outbreak is still unknown.

Introduction

  • In the research article, the authors investigate an outbreak of equine encephalosis virus (EEV) that occurred in Israel between 2008 and 2009.
  • This virus is known to cause fever in horses; however, its appearance in Israel was considered significant as it points towards an emerging infectious disease.

Phylogenetic Analysis

  • The researchers conducted a phylogenetic analysis of these virus strains.
  • They focused on segment 10 of the virus strains and found that these strains form a new cluster within the EEV family, indicating a new or evolved form of the virus.

Sequence Identity to EEV-3

  • The researchers also analyzed segment 2 of the virus strains.
  • Interestingly, they found approximately 92% sequence identity to EEV-3, which is a reference isolate.
  • While this suggests a close relationship between the virus strains causing the outbreak and the EEV-3 isolate, it does not definitively identify EEV-3 as the source of the outbreak.

Source of Outbreak Uncertain

  • Despite the phylogenetic analysis and sequence identity checks, the exact origin or source of this outbreak of equine encephalosis virus remains uncertain.
  • The researchers were unable, in this study, to conclusively detect where this new or evolved version of EEV originated.

Cite This Article

APA
Aharonson-Raz K, Steinman A, Bumbarov V, Maan S, Maan NS, Nomikou K, Batten C, Potgieter C, Gottlieb Y, Mertens P, Klement E. (2011). Isolation and phylogenetic grouping of equine encephalosis virus in Israel. Emerg Infect Dis, 17(10), 1883-1886. https://doi.org/10.3201/eid1710.110350

Publication

Emerging infectious diseases
ISSN: 1080-6059
NlmUniqueID: 9508155
Country: United States
Language: English
Volume: 17
Issue: 10
Pages: 1883-1886

Researcher Affiliations

Aharonson-Raz, Karin
  • The Hebrew University, Rehovot, Israel.
Steinman, Amir
    Bumbarov, Velizar
      Maan, Sushila
        Maan, Narender Singh
          Nomikou, Kyriaki
            Batten, Carrie
              Potgieter, Christiaan
                Gottlieb, Yuval
                  Mertens, Peter
                    Klement, Eyal

                      MeSH Terms

                      • Animals
                      • Cell Line
                      • Chlorocebus aethiops
                      • Disease Outbreaks / veterinary
                      • Horse Diseases / epidemiology
                      • Horse Diseases / virology
                      • Horses
                      • Molecular Sequence Data
                      • Orbivirus / classification
                      • Orbivirus / genetics
                      • Orbivirus / isolation & purification
                      • Phylogeny
                      • RNA, Viral
                      • Reoviridae Infections / epidemiology
                      • Reoviridae Infections / veterinary
                      • Reoviridae Infections / virology
                      • Vero Cells

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                      Citations

                      This article has been cited 9 times.
                      1. Tirosh-Levy S, Steinman A. Equine Encephalosis Virus. Animals (Basel) 2022 Jan 29;12(3).
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                        doi: 10.3390/v13030398pubmed: 33801457google scholar: lookup
                      3. Lecollinet S, Pronost S, Coulpier M, Beck C, Gonzalez G, Leblond A, Tritz P. Viral Equine Encephalitis, a Growing Threat to the Horse Population in Europe?. Viruses 2019 Dec 24;12(1).
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                      4. Maan S, Belaganahalli MN, Maan NS, Potgieter AC, Mertens PPC. Quantitative RT-PCR assays for identification and typing of the Equine encephalosis virus. Braz J Microbiol 2019 Jan;50(1):287-296.
                        doi: 10.1007/s42770-018-0034-1pubmed: 30637652google scholar: lookup
                      5. Yadav PD, Albariño CG, Nyayanit DA, Guerrero L, Jenks MH, Sarkale P, Nichol ST, Mourya DT. Equine Encephalosis Virus in India, 2008. Emerg Infect Dis 2018 May;24(5):898-901.
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