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Isolation of equine coital exanthema virus (equine herpesvirus 3) from the nostril of a foal.

Abstract: The virus causing equine coital exanthema (equine herpesvirus 3) was isolated from a lesion on the nostril of a 2-month-old foal. One week after the mare had returned from a stallion station, vesicular lesions developed on her vulva. They were diagnosed clinically as coital exanthema, and 5 days later a lesion developed on the nostril of her foal. This case is an example of horse-to-horse transmission of coital exanthema virus without coitus. A laboratory diagnosis is necessary to differentiate viruses that cause vesicular lesions about the oral and nasal cavities of horses.
Publication Date: 1985-09-01 PubMed ID: 2997094
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Summary

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The research article is about a study that successfully isolated equine coital exanthema virus, also known as equine herpesvirus 3, from a lesion in a young foal’s nostril, indicating another way the virus can be transmitted among horses without mating.

Study Objective

  • The objective of the study was to investigate the possibility of non-sexual transmission of the equine herpesvirus 3, which typically causes genital lesions in horses.

Research Methodology

  • The study commenced when a mare developed vesicular lesions on her vulva a week after returning from a stallion station. The sores were clinically diagnosed as coital exanthema.
  • Five days later, a lesion appeared on the nostril of the mare’s 2-month-old foal, which prompted further investigations.

Significant Findings

  • The researchers successfully isolated the equine herpesvirus 3 from the lesion on the foal’s nostril. This was a significant finding, as the typical means of transmission was previously thought to be exclusively sexual.
  • The vesicular lesions ordinarily associated with the virus usually manifest around the oral and nasal cavities of horses, pointing to a possible new method of virus transmission.

Conclusions and Implications

  • The successful isolation of the virus confirmed that it is capable of being transmitted from horse to horse without coitus, which shows the importance of laboratory diagnosis in differentiating the cause of vesicular lesions.
  • This revelation can significantly influence management and prevention strategies for equine herpesvirus 3, specifically in settings where horses are kept in close quarters, such as stables and breeding centres.

Cite This Article

APA
Crandell RA, Davis ER. (1985). Isolation of equine coital exanthema virus (equine herpesvirus 3) from the nostril of a foal. J Am Vet Med Assoc, 187(5), 503-504.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 187
Issue: 5
Pages: 503-504

Researcher Affiliations

Crandell, R A
    Davis, E R

      MeSH Terms

      • Animals
      • Female
      • Herpesviridae / isolation & purification
      • Herpesviridae Infections / transmission
      • Herpesviridae Infections / veterinary
      • Herpesvirus 3, Equid / isolation & purification
      • Horse Diseases / microbiology
      • Horse Diseases / transmission
      • Horses
      • Nasal Cavity / microbiology

      Citations

      This article has been cited 4 times.
      1. Vissani MA, Damiani AM, Barrandeguy ME. Equine Coital Exanthema: New Insights on the Knowledge and Leading Perspectives for Treatment and Prevention. Pathogens 2021 Aug 20;10(8).
        doi: 10.3390/pathogens10081055pubmed: 34451519google scholar: lookup
      2. Thorsteinsdóttir L, Guðmundsson GÖ, Jensson H, Torsteinsdóttir S, Svansson V. Isolation of equid alphaherpesvirus 3 from a horse in Iceland with equine coital exanthema. Acta Vet Scand 2021 Feb 2;63(1):6.
        doi: 10.1186/s13028-021-00572-4pubmed: 33531030google scholar: lookup
      3. Kirisawa R, Toishi Y, Akamatsu A, Soejima K, Miyashita T, Tsunoda N. Isolation of equine herpesvirus 3 (EHV-3) from equine coital exanthema of two stallions and sero-epidemiology of EHV-3 infection in Japan. J Vet Med Sci 2017 Mar 23;79(3):636-643.
        doi: 10.1292/jvms.16-0518pubmed: 28132964google scholar: lookup
      4. Bouchey D, Evermann J, Jacob RJ. Molecular pathogenesis of equine coital exanthema (ECE): temperature sensitivity (TS) and restriction endonuclease (RE) fragment profiles of several field isolates. Arch Virol 1987;92(3-4):293-9.
        doi: 10.1007/BF01317485pubmed: 3028334google scholar: lookup