Journal of veterinary pharmacology and therapeutics1984; 7(1); 1-16; doi: 10.1111/j.1365-2885.1984.tb00872.x

Ivermectin: a review of efficacy and safety.

Abstract: No abstract available
Publication Date: 1984-03-01 PubMed ID: 6368862DOI: 10.1111/j.1365-2885.1984.tb00872.xGoogle Scholar: Lookup
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  • Journal Article
  • Review

Cite This Article

APA
Campbell WC, Benz GW. (1984). Ivermectin: a review of efficacy and safety. J Vet Pharmacol Ther, 7(1), 1-16. https://doi.org/10.1111/j.1365-2885.1984.tb00872.x

Publication

ISSN: 0140-7783
NlmUniqueID: 7910920
Country: England
Language: English
Volume: 7
Issue: 1
Pages: 1-16

Researcher Affiliations

Campbell, W C
    Benz, G W

      MeSH Terms

      • Animals
      • Animals, Domestic
      • Anthelmintics / therapeutic use
      • Cattle
      • Cattle Diseases / drug therapy
      • Chemical Phenomena
      • Chemistry
      • Dog Diseases / drug therapy
      • Dogs
      • Ectoparasitic Infestations / drug therapy
      • Ectoparasitic Infestations / veterinary
      • Goats
      • Horse Diseases / drug therapy
      • Horses
      • Insecticides / therapeutic use
      • Ivermectin
      • Lactones / therapeutic use
      • Nematode Infections / drug therapy
      • Nematode Infections / veterinary
      • Poultry
      • Poultry Diseases / drug therapy
      • Safety
      • Sheep
      • Sheep Diseases / drug therapy
      • Swine
      • Swine Diseases / drug therapy

      Citations

      This article has been cited 38 times.
      1. Nabi-Afjadi M, Mohebi F, Zalpoor H, Aziziyan F, Akbari A, Moradi-Sardareh H, Bahreini E, Moeini AM, Effatpanah H. A cellular and molecular biology-based update for ivermectin against COVID-19: is it effective or non-effective?. Inflammopharmacology 2023 Feb;31(1):21-35.
        doi: 10.1007/s10787-022-01129-1pubmed: 36609716google scholar: lookup
      2. Beckers E, Casselman I, Soudant E, Daminet S, Paepe D, Peelman L, Broeckx BJG. The prevalence of the ABCB1-1u0394 variant in a clinical veterinary setting: The risk of not genotyping.. PLoS One 2022;17(8):e0273706.
        doi: 10.1371/journal.pone.0273706pubmed: 36037240google scholar: lookup
      3. Coultous RM, Sutton DGM, Boden LA. A risk assessment of equine piroplasmosis entry, exposure and consequences in the UK.. Equine Vet J 2023 Mar;55(2):282-294.
        doi: 10.1111/evj.13579pubmed: 35478189google scholar: lookup
      4. Marchenko VA, Khalikov SS, Efremova EA, Ilyin Ju MM. Efficacy of Novel Formulations of Ivermectin and Albendazole in Parasitic Infections of Sheep in the Altai Mountains of Russia.. Iran J Parasitol 2021 Apr-Jun;16(2):199-208.
        doi: 10.18502/ijpa.v16i2.6268pubmed: 34557234google scholar: lookup
      5. Dash P, Mohapatra S, Ghosh S, Nayak B. A Scoping Insight on Potential Prophylactics, Vaccines and Therapeutic Weaponry for the Ongoing Novel Coronavirus (COVID-19) Pandemic- A Comprehensive Review.. Front Pharmacol 2020;11:590154.
        doi: 10.3389/fphar.2020.590154pubmed: 33815095google scholar: lookup
      6. Elalfy H, Besheer T, El-Mesery A, El-Gilany AH, Soliman MA, Alhawarey A, Alegezy M, Elhadidy T, Hewidy AA, Zaghloul H, Neamatallah MAM, Raafat D, El-Emshaty WM, Abo El Kheir NY, El-Bendary M. Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID-19.. J Med Virol 2021 May;93(5):3176-3183.
        doi: 10.1002/jmv.26880pubmed: 33590901google scholar: lookup
      7. Moroni B, Valldeperes M, Serrano E, Lu00f3pez-Olvera JR, Lavu00edn S, Rossi L. Comment on: "The treatment of sarcoptic mange in wildlife: a systematic review".. Parasit Vectors 2020 Sep 15;13(1):471.
        doi: 10.1186/s13071-020-04347-0pubmed: 32933573google scholar: lookup
      8. Sharun K, Dhama K, Patel SK, Pathak M, Tiwari R, Singh BR, Sah R, Bonilla-Aldana DK, Rodriguez-Morales AJ, Leblebicioglu H. Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19.. Ann Clin Microbiol Antimicrob 2020 May 30;19(1):23.
        doi: 10.1186/s12941-020-00368-wpubmed: 32473642google scholar: lookup
      9. Ahmadpour E, Godrati-Azar Z, Spotin A, Norouzi R, Hamishehkar H, Nami S, Heydarian P, Rajabi S, Mohammadi M, Perez-Cordon G. Nanostructured lipid carriers of ivermectin as a novel drug delivery system in hydatidosis.. Parasit Vectors 2019 Oct 10;12(1):469.
        doi: 10.1186/s13071-019-3719-xpubmed: 31601244google scholar: lookup
      10. Page AP. The sensory amphidial structures of Caenorhabditis elegans are involved in macrocyclic lactone uptake and anthelmintic resistance.. Int J Parasitol 2018 Nov;48(13):1035-1042.
        doi: 10.1016/j.ijpara.2018.06.003pubmed: 30253131google scholar: lookup
      11. Chen IS, Kubo Y. Ivermectin and its target molecules: shared and unique modulation mechanisms of ion channels and receptors by ivermectin.. J Physiol 2018 May 15;596(10):1833-1845.
        doi: 10.1113/JP275236pubmed: 29063617google scholar: lookup
      12. Dey S, Kurade NP, Khurana KL, Dan A. Clinicobiochemical changes in ivermectin toxicity in Doberman pinscher pups.. J Parasit Dis 2017 Jun;41(2):580-583.
        doi: 10.1007/s12639-016-0806-1pubmed: 28615883google scholar: lookup
      13. Northover AS, Godfrey SS, Lymbery AJ, Morris K, Wayne AF, Thompson RC. Evaluating the Effects of Ivermectin Treatment on Communities of Gastrointestinal Parasites in Translocated Woylies (Bettongia penicillata).. Ecohealth 2017 Mar;14(Suppl 1):117-127.
        doi: 10.1007/s10393-015-1088-2pubmed: 26719294google scholar: lookup
      14. Walther FM, Allan MJ, Roepke RK. Plasma pharmacokinetic profile of fluralaner (Bravectou2122) and ivermectin following concurrent administration to dogs.. Parasit Vectors 2015 Oct 6;8:508.
        doi: 10.1186/s13071-015-1123-8pubmed: 26438338google scholar: lookup
      15. Jacobs CT, Scholtz CH. A review on the effect of macrocyclic lactones on dung-dwelling insects: Toxicity of macrocyclic lactones to dung beetles.. Onderstepoort J Vet Res 2015 Apr 16;82(1):858.
        doi: 10.4102/ojvr.v82i1.858pubmed: 26017637google scholar: lookup
      16. Suu00e1rez G, Alvarez L, Castells D, Correa O, Fagiolino P, Lanusse C. Relative bioavailability and comparative clinical efficacy of different ivermectin oral formulations in lambs.. BMC Vet Res 2013 Feb 11;9:27.
        doi: 10.1186/1746-6148-9-27pubmed: 23398629google scholar: lookup
      17. Babalola OE. Ocular onchocerciasis: current management and future prospects.. Clin Ophthalmol 2011;5:1479-91.
        doi: 10.2147/OPTH.S8372pubmed: 22069350google scholar: lookup
      18. Geyer J, Janko C. Treatment of MDR1 mutant dogs with macrocyclic lactones.. Curr Pharm Biotechnol 2012 May;13(6):969-86.
        doi: 10.2174/138920112800399301pubmed: 22039792google scholar: lookup
      19. Fu Y, Nie HM, Niu LL, Xie Y, Deng JB, Wang Q, Yang GY, Gu XB, Wang SX. Comparative efficacy of ivermectin and levamisole for reduction of migrating and encapsulated larvae of Baylisascaris transfuga in mice.. Korean J Parasitol 2011 Jun;49(2):145-51.
        doi: 10.3347/kjp.2011.49.2.145pubmed: 21738270google scholar: lookup
      20. Brayden DJ, Griffin J. Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers.. Vet Res Commun 2008 Jan;32(1):93-106.
        doi: 10.1007/s11259-007-9007-9pubmed: 17578674google scholar: lookup
      21. Bell RJ, Holste JE. Efficacy of ivermectin oral liquid for horses.. Can Vet J 1990 Jul;31(7):519-21.
        pubmed: 17423630
      22. Bauck SW, Jim GK, Guichon PT, Newcomb KM, Cox JL, Barrick RA. Comparative cost-effectiveness of ivermectin versus topical organophosphate in feedlot calves.. Can Vet J 1989 Feb;30(2):161-4.
        pubmed: 17423237
      23. Sanford SE, Rehmtulla AJ, Josephson GK. Ivermectin overdose and toxicosis in neonatal pigs.. Can Vet J 1988 Sep;29(9):735-6.
        pubmed: 17423121
      24. Barragry TB. A review of the pharmacology and clinical uses of ivermectin.. Can Vet J 1987 Aug;28(8):512-7.
        pubmed: 17422843
      25. de Souza Chagas AC, da Silva Vieira L, Rodrigues Aragu00e3o W, do Carmo Navarro AM, Vasques Villela LC. Anthelmintic action of eprinomectin in lactating Anglo-Nubian goats in Brazil.. Parasitol Res 2007 Jan;100(2):391-4.
        doi: 10.1007/s00436-006-0316-7pubmed: 17031697google scholar: lookup
      26. Tisler T, Kozuh Erzen N. Abamectin in the aquatic environment.. Ecotoxicology 2006 Aug;15(6):495-502.
        doi: 10.1007/s10646-006-0085-1pubmed: 16741677google scholar: lookup
      27. Erzen NK, Kolar L, Flajs VC, Kuzner J, Marc I, Pogacnik M. Degradation of abamectin and doramectin on sheep grazed pasture.. Ecotoxicology 2005 Aug;14(6):627-35.
        doi: 10.1007/s10646-005-0012-xpubmed: 16215697google scholar: lookup
      28. Alvinerie M, Lacoste E, Sutra JF, Chartier C. Some pharmacokinetic parameters of eprinomectin in goats following pour-on administration.. Vet Res Commun 1999 Nov;23(7):449-55.
        doi: 10.1023/a:1006373609314pubmed: 10598075google scholar: lookup
      29. Fricker G, Gutmann H, Droulle A, Drewe J, Miller DS. Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules.. Pharm Res 1999 Oct;16(10):1570-5.
        doi: 10.1023/a:1018956621376pubmed: 10554099google scholar: lookup
      30. Oksanen A, Nieminen M. Moxidectin as an endectocide in reindeer.. Acta Vet Scand 1998;39(4):483-9.
        doi: 10.1186/BF03547774pubmed: 9926462google scholar: lookup
      31. Cleland TA. Inhibitory glutamate receptor channels.. Mol Neurobiol 1996 Oct;13(2):97-136.
        doi: 10.1007/BF02740637pubmed: 8938647google scholar: lookup
      32. Lo PK, Fink DW, Williams JB, Blodinger J. Pharmacokinetic studies of ivermectin: effects of formulation.. Vet Res Commun 1985 Sep;9(4):251-68.
        doi: 10.1007/BF02215150pubmed: 3841626google scholar: lookup
      33. Omura S. Philosophy of new drug discovery.. Microbiol Rev 1986 Sep;50(3):259-79.
        doi: 10.1128/mr.50.3.259-279.1986pubmed: 3534537google scholar: lookup
      34. Sani BP, Vaid A. Specific interaction of ivermectin with retinol-binding protein from filarial parasites.. Biochem J 1988 Feb 1;249(3):929-32.
        doi: 10.1042/bj2490929pubmed: 3355505google scholar: lookup
      35. Soll MD, Carmichael IH, Swan GE, Gross SJ. Control of induced infestations of three African multihost tick species with sustained-release ivermectin.. Exp Appl Acarol 1989 Jul;7(2):121-30.
        doi: 10.1007/BF01270432pubmed: 2766895google scholar: lookup
      36. Jackson HC, Chesterman MP. In-vivo effects of ivermectin on Rhipicephalus appendiculatus: the influence of tick feeding patterns and drug pharmacokinetics.. Exp Appl Acarol 1989 Jul;7(2):109-19.
        doi: 10.1007/BF01270431pubmed: 2766894google scholar: lookup
      37. Martin RJ, Pennington AJ. A patch-clamp study of effects of dihydroavermectin on Ascaris muscle.. Br J Pharmacol 1989 Nov;98(3):747-56.
      38. Martin RJ, Kusel JR, Robertson SJ, Minta A, Haugland RP. Distribution of a fluorescent ivermectin probe, bodipy ivermectin, in tissues of the nematode parasite Ascaris suum.. Parasitol Res 1992;78(4):341-8.
        doi: 10.1007/BF00937094pubmed: 1409535google scholar: lookup