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The Veterinary clinics of North America. Equine practice1987; 3(3); 585-615; doi: 10.1016/s0749-0739(17)30666-1

Laboratory diagnosis and characterization of renal disease in horses.

Abstract: Laboratory evaluation of renal function in horses has advanced dramatically in the last 10 years largely as a result of the interest generated by the creative approach to diagnostic indices taken by Brobst, Traver, Coffman, and others. Some methods of assessing renal function discussed here are clearly outside the scope of a practice environment but are available in referral hospitals for use in difficult or unusual cases. Other methods described, such as calculation of fractional excretions and urine to serum creatinine ratios, are accessible and readily interpreted by the veterinary practitioner. These diagnostic methods should help in the early identification of renal disease in horses and therefore should allow veterinarians the option to treat renal disease before renal failure is advanced. In addition, practitioners may be able to offer more informed prognoses after a more complete evaluation of renal function.
Publication Date: 1987-12-01 PubMed ID: 3322528DOI: 10.1016/s0749-0739(17)30666-1Google Scholar: Lookup
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Summary

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The research is focused on the development and application of advanced methods for diagnosing and characterizing renal disease in horses, which can be used in different settings to improve early detection and treatment results.

Improvements in Laboratory Evaluation of Renal Function in Horses

  • The laboratory evaluation of renal function in horses has seen significant improvements over the last decade. This has been largely driven by innovation in diagnostic indices pursued by various researchers such as Brobst, Traver, and Coffman.
  • These advancements in methods to assess renal function have expanded the capabilities of veterinarians in detecting and dealing with renal diseases in horses.

Application of Advanced Methods in Different Settings

  • While some of the discussed methods for assessing renal function are complex and may not be suitable for typical veterinary practices, they are nevertheless available in specialized referral hospitals and can be used in tricky or unusual cases.
  • Other methods, such as the calculation of fractional excretions and urine to serum creatinine ratios, are more accessible and can be easily interpreted by most veterinary practitioners.

Benefits of Advanced Diagnostic Methods

  • The utilization of these advanced diagnostic methods can allow for early detection of renal disease in horses. This early identification gives veterinarians the opportunity to initiate treatment before the disease progresses to advanced renal failure.
  • Moreover, by providing a more comprehensive evaluation of renal function, these methods can improve the ability of practitioners to give more informed prognoses of the disease.

Cite This Article

APA
Kohn CW, Chew DJ. (1987). Laboratory diagnosis and characterization of renal disease in horses. Vet Clin North Am Equine Pract, 3(3), 585-615. https://doi.org/10.1016/s0749-0739(17)30666-1

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 3
Issue: 3
Pages: 585-615

Researcher Affiliations

Kohn, C W
  • Department of Veterinary Clinical Sciences, Ohio State University College of Veterinary Medicine, Columbus.
Chew, D J

    MeSH Terms

    • Animals
    • Glomerular Filtration Rate / veterinary
    • Horse Diseases / diagnosis
    • Horse Diseases / urine
    • Horses
    • Kidney Diseases / diagnosis
    • Kidney Diseases / urine
    • Kidney Diseases / veterinary
    • Kidney Function Tests / veterinary

    Citations

    This article has been cited 2 times.
    1. Matsuda H, Matsuda K, Muko R, Oikawa MA, Tanaka A. Short-term infusion of ultralow-dose dopamine in an adult horse with acute kidney injury: A case report. Vet Anim Sci 2021 Jun;12:100176.
      doi: 10.1016/j.vas.2021.100176pubmed: 33912729google scholar: lookup
    2. Arosalo BM, Raekallio M, Rajamäki M, Holopainen E, Kastevaara T, Salonen H, Sankari S. Detecting early kidney damage in horses with colic by measuring matrix metalloproteinase -9 and -2, other enzymes, urinary glucose and total proteins. Acta Vet Scand 2007 Jan 23;49(1):4.
      doi: 10.1186/1751-0147-49-4pubmed: 17244354google scholar: lookup