Lawsonia intracellularis-associated ulcerative and necro-hemorrhagic enteritis in 5 weanling foals.
Abstract: This report describes 5 cases of fatal Lawsonia intracellularis-associated ulcerative and necro-hemorrhagic enteritis in weanling Thoroughbred and Standardbred foals. The lesions are similar to those of the L. intracellularis-associated ulcerative and necro-hemorrhagic enteritis syndrome in pigs. Two foals had concurrent severe typhlo-colitis as a result of a large burden of encysted cyathostomes. The clinical, diagnostic, and therapeutic challenges, and the potential complications encountered during the management of such cases are discussed. Entérite ulcérative et nécro-hémorragique associée àLawsonia intracellularischez 5 poulains sevrés. Ce rapport décrit 5 cas mortels d’entérite ulcérative et nécro-hémorragique associée à Lawsonia intracellularis chez des poulains Thoroughbred et Standardbred. Les lésions sont semblables à celles du syndrome de l’entérite ulcérative et nécro-hémorragique associée à L. intracellularis chez les porcs. Deux poulains étaient atteints d’une typhlo-colite grave concomitante en raison d’une charge importante de cyathostomes enkystés. Les difficultés cliniques, diagnostiques et thérapeutiques ainsi que les complications potentielles rencontrées durant la gestion de ces cas sont analysées.(Traduit par Isabelle Vallières).
Publication Date: 2013-10-25 PubMed ID: 24155489PubMed Central: PMC3743569
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Summary
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This research article discusses the documentation of 5 fatal cases of a specific disease (Lawsonia intracellularis-associated ulcerative and necro-hemorrhagic enteritis) in weanling Thoroughbred and Standardbred foals, similar to one seen in pigs. Issues surrounding diagnosis, treatment, and managing potential complications are also considered.
Diseases and Animals Involved
- The study involves research on weanling Thoroughbred and Standardbred foals – specifically, it reports on five cases where these young horses were affected by a severe disease.
- The disease in question is known as Lawsonia intracellularis-associated ulcerative and necro-hemorrhagic enteritis.
- This specific disease condition is akin to a syndrome seen in pigs, suggesting a possible interspecies similarity in disease manifestation.
Concurrent Conditions and Complications
- In two of the foals, severe typhlo-colitis occurred simultaneously with the aforementioned disease due to a high burden of encysted cyathostomes – a type of parasitic worm. This suggests that secondary infections or co-existing conditions could exacerbate the severity of the syndrome.
Clinical, Diagnostic, and Therapeutic Challenges
- This study highlights the difficulties involved in the clinical management of such cases, including diagnostic and therapeutic challenges. Recognizing the complex nature of these cases implies that there may be a need for advanced diagnostic tools and specialized treatments.
- We also learn that potential complications can arise during the management of such cases, suggesting the disease’s intricate pathogenesis and the multifaceted strategies required for successful management. The need to preempt and prepare for such complications is also implicated here.
Overall Contributions and Implications of the Study
- This study makes a significant contribution to veterinary literature on Lawsonia intracellularis-associated enteritis in foals.
- Understanding these case studies and related challenges can further medical knowledge, enhance diagnostic skills, inform treatment strategies, and improve overall disease management.
- The study involves research on weanling Thoroughbred and Standardbred foals – specifically, it reports on five cases where these young horses were affected by a severe disease.
- The disease in question is known as Lawsonia intracellularis-associated ulcerative and necro-hemorrhagic enteritis.
- This specific disease condition is akin to a syndrome seen in pigs, suggesting a possible interspecies similarity in disease manifestation.
Concurrent Conditions and Complications
- In two of the foals, severe typhlo-colitis occurred simultaneously with the aforementioned disease due to a high burden of encysted cyathostomes – a type of parasitic worm. This suggests that secondary infections or co-existing conditions could exacerbate the severity of the syndrome.
Clinical, Diagnostic, and Therapeutic Challenges
- This study highlights the difficulties involved in the clinical management of such cases, including diagnostic and therapeutic challenges. Recognizing the complex nature of these cases implies that there may be a need for advanced diagnostic tools and specialized treatments.
- We also learn that potential complications can arise during the management of such cases, suggesting the disease’s intricate pathogenesis and the multifaceted strategies required for successful management. The need to preempt and prepare for such complications is also implicated here.
Overall Contributions and Implications of the Study
- This study makes a significant contribution to veterinary literature on Lawsonia intracellularis-associated enteritis in foals.
- Understanding these case studies and related challenges can further medical knowledge, enhance diagnostic skills, inform treatment strategies, and improve overall disease management.
- In two of the foals, severe typhlo-colitis occurred simultaneously with the aforementioned disease due to a high burden of encysted cyathostomes – a type of parasitic worm. This suggests that secondary infections or co-existing conditions could exacerbate the severity of the syndrome.
Clinical, Diagnostic, and Therapeutic Challenges
- This study highlights the difficulties involved in the clinical management of such cases, including diagnostic and therapeutic challenges. Recognizing the complex nature of these cases implies that there may be a need for advanced diagnostic tools and specialized treatments.
- We also learn that potential complications can arise during the management of such cases, suggesting the disease’s intricate pathogenesis and the multifaceted strategies required for successful management. The need to preempt and prepare for such complications is also implicated here.
Overall Contributions and Implications of the Study
- This study makes a significant contribution to veterinary literature on Lawsonia intracellularis-associated enteritis in foals.
- Understanding these case studies and related challenges can further medical knowledge, enhance diagnostic skills, inform treatment strategies, and improve overall disease management.
- This study highlights the difficulties involved in the clinical management of such cases, including diagnostic and therapeutic challenges. Recognizing the complex nature of these cases implies that there may be a need for advanced diagnostic tools and specialized treatments.
- We also learn that potential complications can arise during the management of such cases, suggesting the disease’s intricate pathogenesis and the multifaceted strategies required for successful management. The need to preempt and prepare for such complications is also implicated here.
Overall Contributions and Implications of the Study
- This study makes a significant contribution to veterinary literature on Lawsonia intracellularis-associated enteritis in foals.
- Understanding these case studies and related challenges can further medical knowledge, enhance diagnostic skills, inform treatment strategies, and improve overall disease management.
- This study makes a significant contribution to veterinary literature on Lawsonia intracellularis-associated enteritis in foals.
- Understanding these case studies and related challenges can further medical knowledge, enhance diagnostic skills, inform treatment strategies, and improve overall disease management.
Cite This Article
APA
Arroyo LG, Ter Woort F, Baird JD, Tatiersky L, Delay J, van Dreumel T.
(2013).
Lawsonia intracellularis-associated ulcerative and necro-hemorrhagic enteritis in 5 weanling foals.
Can Vet J, 54(9), 853-858.
Publication
Researcher Affiliations
- Department of Clinical Studies (Arroyo, ter Woort, Baird), and Department of Pathobiology (Tatiersky), Ontario Veterinary College; Animal Health Laboratory (DeLay, van Dreumel), University of Guelph, Guelph, Ontario N1G 2W1.
MeSH Terms
- Animals
- Desulfovibrionaceae Infections / diagnosis
- Desulfovibrionaceae Infections / microbiology
- Desulfovibrionaceae Infections / pathology
- Desulfovibrionaceae Infections / veterinary
- Enteritis / microbiology
- Enteritis / pathology
- Enteritis / veterinary
- Fatal Outcome
- Female
- Horse Diseases / microbiology
- Horse Diseases / pathology
- Horses
- Lawsonia Bacteria
- Male
References
This article includes 22 references
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Citations
This article has been cited 2 times.- Kopper JJ, Willette JA, Kogan CJ, Seguin A, Bolin SR, Schott HC 2nd. Detection of pathogens in blood or feces of adult horses with enteric disease and association with outcome of colitis. J Vet Intern Med 2021 Sep;35(5):2465-2472.
- Bohlin AM, Olsen SN, Laursen SH, Öhman A, van Galen G. Lawsonia intracellularis associated equine proliferative enteropathy in Danish weanling foals. Acta Vet Scand 2019 Mar 8;61(1):12.
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