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Limb deformities in foals associated with ingestion of locoweed by mares.

Abstract: Five of 26 pregnant mares observed ingesting locoweed (Astragalus mollisimus) subsequently aborted and another 10 produced foals with various limb deformities. Seven of the foals had deformities of a flexion-extension type and 3 had angular deformities. Four foals were normal. The limb deformities either resolved spontaneously (5 cases) or were treated successfully (in 4 of the other 5 cases). The problems of abortion and limb deformities were attributed to locoweed ingestion on the basis of the mares having eaten the plants, and the similarity of the syndrome to that previously reported in sheep and cattle.
Publication Date: 1982-08-01 PubMed ID: 7107503
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Summary

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This study observes foals born with limb deformities, linked to their pregnant mothers’ consumption of a plant known as locoweed. The research builds on similar previous findings in sheep and cattle.

Objective and Methodology

The objective of this research was to investigate the association between consumption of locoweed (Astragalus mollisimus) by pregnant mares and subsequent developmental problems in their offspring. Out of a total of 26 observed mares, 5 aborted and 10 gave birth to foals with various limb deformities.

Findings

  • Among the deformities identified, 7 were classified as flexion-extension type deformities, while 3 were described as angular deformities.
  • Four foals were born without any noticeable issue.
  • The deformities exhibited in some foals self-resolved in 5 cases, while in 4 other cases, medical treatment was required and successful.

Conclusion

The study concluded that there is a probable link between locoweed consumption by pregnant mares and the incidence of limb deformities in foals. This conclusion was based on:

  • The fact that the mares had eaten locoweed during pregnancy.
  • The similarity of the observed syndrome to previously documented cases in other livestock species, such as sheep and cattle, which also ate locoweed.

The study paves the way for more research to understand the full extent of the relationship between locoweed ingestion and negative offspring outcomes in mares, as well as to assess whether similar risks exist for other livestock.

Cite This Article

APA
McIlwraith CW, James LF. (1982). Limb deformities in foals associated with ingestion of locoweed by mares. J Am Vet Med Assoc, 181(3), 255-258.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 181
Issue: 3
Pages: 255-258

Researcher Affiliations

McIlwraith, C W
    James, L F

      MeSH Terms

      • Abortion, Veterinary / etiology
      • Animals
      • Female
      • Forelimb / abnormalities
      • Hindlimb / abnormalities
      • Horse Diseases / congenital
      • Horse Diseases / etiology
      • Horses
      • Male
      • Plant Poisoning / veterinary
      • Pregnancy
      • Pregnancy Complications / etiology
      • Pregnancy Complications / veterinary

      Citations

      This article has been cited 2 times.
      1. Muirhead TL, Pack L, Radtke CL. Unilateral notomelia in a newborn Holstein calf. Can Vet J 2014 Jul;55(7):659-62.
        pubmed: 24982517
      2. Allen AL, Doige CE, Fretz PB, Townsend HG. Hyperplasia of the thyroid gland and concurrent musculoskeletal deformities in western Canadian foals: reexamination of a previously described syndrome. Can Vet J 1994 Jan;35(1):31-8.
        pubmed: 8044756