FREE SHIPPING over $40
OVER 10000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Anatomy and embryology1996; 193(2); 175-179; doi: 10.1007/BF00214708

Lymph pathways associated with three types of follicle structure found in gut-associated lymphoid tissue of horse ileum.

Abstract: In the horse ileum, lacteals in the villi are continuous with prelymphatic intercellular channels and a plexus of lymphatic sinuses in the lamina propria that encircle the domes of the follicle/dome structures and proprial follicles. These sinuses may act as the major entry site for many of the lymphocytes migrating from gut-associated lymphoid tissue via the lymphatic system. Vessels from this plexus penetrate the muscularis mucosae and lymph flows into lymphatic vessels within the interfollicular tissue between the follicles of both follicle/dome structures and lymphoglandular complexes (LGCs). No lymphatic vessels leave the follicles, but intercellular pathways of the follicles are continuous with those in the surrounding interfollicular tissue and follicular sinuses around the base of the follicles. These pathways appear to provide the only available lymphatic route for lymphocytes leaving LGCs to enter the lymphatic system. Lymph from the interfollicular tissue enters deep submucosal lymphatic vessels, containing prominent valves, which drain into other vessels transporting lymph from the surface of the ileum.
Get Full Text
Publication Date: 1996-02-01 PubMed ID: 8742058DOI: 10.1007/BF00214708Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research study investigates the different lymph pathways connected to three types of follicle structures in the gut-associated lymphoid tissue of a horse’s ileum.

Study Overview

The study delves into how lymph pathways in horse ileum, especially the ones present in the villi or tiny projections on the inner surface of the gut, are interconnected with prelymphatic intercellular channels. It also investigates how these pathways are linked to a network of lymphatic sinuses in the lamina propria.

  • The examination suggests that these sinuses might serve as major gateways for the migration of lymphocytes from gut-associated lymphoid tissue through the lymphatic system.
  • The vessels from the plexus penetrate the muscular layer of the mucous membrane, channeling the lymph fluid into lymphatic vessels within the interfollicular tissue.
  • This interfollicular tissue occurs between the follicles of follicle/dome structures and lymphoglandular complexes (LGCs), a part of the horse’s immune system in the digestive tract.

Lymphatic Pathways within Follicles

The research states that no lymphatic vessels emerge from the follicles, but the intercellular pathways present in the follicles are interlinked with those in the surrounding interfollicular tissue. This interconnection is further extended to the follicular sinuses located around the base of the follicles.

  • According to the study’s findings, these pathways seem to provide the only viable lymphatic route for lymphocytes leaving LGCs to enter the lymphatic system.

Deep Submucosal Lymphatic Vessels

Another pivotal discovery made in this study is that the lymph from the interfollicular tissue enters deep submucosal lymphatic vessels. These vessels are characterized by their prominent valves.

  • These deep submucosal lymphatic vessels are responsible for draining into others, which then carry the lymph from the surface of the ileum.

In conclusion, this study enhances our understanding of the lymphatic system in the horse ileum by exposing the associations between different lymphatic pathways and follicle structures present in the gut-associated lymphoid tissue. Understanding these interactions is essential for improving veterinary treatments related to the lymphatic system.

Cite This Article

APA
Lowden S, Heath T. (1996). Lymph pathways associated with three types of follicle structure found in gut-associated lymphoid tissue of horse ileum. Anat Embryol (Berl), 193(2), 175-179. https://doi.org/10.1007/BF00214708

Publication

Anatomy and embryology
ISSN: 0340-2061
NlmUniqueID: 7505194
Country: Germany
Language: English
Volume: 193
Issue: 2
Pages: 175-179

Researcher Affiliations

Lowden, S
  • Department of Anatomical Sciences, University of Queensland, Brisbane, Australia.
Heath, T

    MeSH Terms

    • Animals
    • Horses / anatomy & histology
    • Ileum / anatomy & histology
    • Lymphatic System / anatomy & histology
    • Lymphoid Tissue / anatomy & histology
    • Microscopy, Electron
    • Microscopy, Electron, Scanning

    References

    This article includes 16 references
    1. Ohtani O, Murakami T. Organization of the lymphatic vessels and their relationships to blood vessels in rabbit Peyer's patches.. Arch Histol Cytol 1990;53 Suppl:155-64.
      pubmed: 2252627doi: 10.1679/aohc.53.suppl_155google scholar: lookup
    2. Lowden S, Heath T. Ileal Peyer's patches in pigs: intercellular and lymphatic pathways.. Anat Rec 1994 Jul;239(3):297-305.
      pubmed: 7943761doi: 10.1002/ar.1092390308google scholar: lookup
    3. Chu RM, Liu CH. Morphological and functional comparisons of Peyer's patches in different parts of the swine small intestine.. Vet Immunol Immunopathol 1984 Jul;6(3-4):391-403.
      pubmed: 6485244doi: 10.1016/0165-2427(84)90063-1google scholar: lookup
    4. Landsverk T, Halleraker M, Aleksandersen M, McClure S, Hein W, Nicander L. The intestinal habitat for organized lymphoid tissues in ruminants; comparative aspects of structure, function and development.. Vet Immunol Immunopathol 1991 Mar;28(1):1-16.
      pubmed: 1905075doi: 10.1016/0165-2427(91)90038-egoogle scholar: lookup
    5. Bennell MA, Husband AJ. Route of lymphocyte migration in pigs. I. Lymphocyte circulation in gut-associated lymphoid tissue.. Immunology 1981 Mar;42(3):469-74.
      pubmed: 7203532
    6. Lowden S, Heath T. Lymph pathways associated with Peyer's patches in sheep.. J Anat 1992 Oct;181 ( Pt 2)(Pt 2):209-17.
      pubmed: 1295861
    7. Liebler EM, Pohlenz JF, Woode GN. Gut-associated lymphoid tissue in the large intestine of calves. I. Distribution and histology.. Vet Pathol 1988 Nov;25(6):503-8.
      pubmed: 3212894doi: 10.1177/030098588802500614google scholar: lookup
    8. Liebler EM, Pohlenz JF, Cheville NF. Gut-associated lymphoid tissue in the large intestine of calves. II. Electron microscopy.. Vet Pathol 1988 Nov;25(6):509-15.
      pubmed: 3212895doi: 10.1177/030098588802500615google scholar: lookup
    9. Lowden S, Heath T. Lymphoid tissues of the ileum in young horses: distribution, structure, and epithelium.. Anat Embryol (Berl) 1995 Aug;192(2):171-9.
      pubmed: 7486013doi: 10.1007/BF00186005google scholar: lookup
    10. Nieuwenhuis P, Gastkemper NA, Opstelten D. Histophysiology of follicular structures and germinal centres in relation to B cell differentiation.. Ciba Found Symp 1981;84:246-64.
      pubmed: 7023873doi: 10.1002/9780470720660.ch13google scholar: lookup
    11. Liebler EM, Paar M, Pohlenz JF. M cells in the rectum of calves.. Res Vet Sci 1991 Jul;51(1):107-14.
      pubmed: 1896624doi: 10.1016/0034-5288(91)90040-ugoogle scholar: lookup
    12. Pabst R, Reynolds JD. Emigration of newly formed lymphocytes from ileal Peyer's patches in lambs.. Adv Exp Med Biol 1985;186:655-60.
      pubmed: 4050594doi: 10.1007/978-1-4613-2463-8_80google scholar: lookup
    13. Berens von Rautenfeld D, Lubach D, Wenzel-Hora BI, Hunneshagen C, Deutsch A. Vacuum injection--a new indirect fixing method for the demonstration of initial lymphatics in biopsy specimens of human organs.. Acta Anat (Basel) 1989;136(2):172-6.
      pubmed: 2510449doi: 10.1159/000146819google scholar: lookup
    14. Reynolds JD, Pabst R. The emigration of lymphocytes from Peyer's patches in sheep.. Eur J Immunol 1984 Jan;14(1):7-13.
      pubmed: 6692840doi: 10.1002/eji.1830140103google scholar: lookup
    15. Reynolds J, Pabst R, Bordmann G. Evidence for the existence of two distinct types of Peyer's patches in sheep.. Adv Exp Med Biol 1985;186:101-9.
      pubmed: 4050580doi: 10.1007/978-1-4613-2463-8_12google scholar: lookup
    16. Reynolds JD, Kennedy L, Peppard J, Pabst R. Ileal Peyer's patch emigrants are predominantly B cells and travel to all lymphoid tissues in sheep.. Eur J Immunol 1991 Feb;21(2):283-9.
      pubmed: 1900239doi: 10.1002/eji.1830210207google scholar: lookup

    Citations

    This article has been cited 1 times.
    1. Diana A, Freccero F, Giancola F, Linta N, Pietra M, Luca V, Salamanca G, Cipone M, Chiocchetti R. Ex vivo ultrasonographic and histological morphometry of small intestinal wall layers in horses. Vet Radiol Ultrasound 2022 May;63(3):353-363.
      doi: 10.1111/vru.13059pubmed: 35171532google scholar: lookup
    Subscribe to our newsletter
    Join 100,113 horse owners like you who receive our email updates on horse health and nutrition.