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Home / Equine Research Bank / Anat Embryol (Berl) / Lymph pathways associated with three types of follicle struc...
Anatomy and embryology1996; 193(2); 175-179; doi: 10.1007/BF00214708

Lymph pathways associated with three types of follicle structure found in gut-associated lymphoid tissue of horse ileum.

Abstract: In the horse ileum, lacteals in the villi are continuous with prelymphatic intercellular channels and a plexus of lymphatic sinuses in the lamina propria that encircle the domes of the follicle/dome structures and proprial follicles. These sinuses may act as the major entry site for many of the lymphocytes migrating from gut-associated lymphoid tissue via the lymphatic system. Vessels from this plexus penetrate the muscularis mucosae and lymph flows into lymphatic vessels within the interfollicular tissue between the follicles of both follicle/dome structures and lymphoglandular complexes (LGCs). No lymphatic vessels leave the follicles, but intercellular pathways of the follicles are continuous with those in the surrounding interfollicular tissue and follicular sinuses around the base of the follicles. These pathways appear to provide the only available lymphatic route for lymphocytes leaving LGCs to enter the lymphatic system. Lymph from the interfollicular tissue enters deep submucosal lymphatic vessels, containing prominent valves, which drain into other vessels transporting lymph from the surface of the ileum.
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Publication Date: 1996-02-01 PubMed ID: 8742058DOI: 10.1007/BF00214708Google Scholar: Lookup
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Summary

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This research study investigates the different lymph pathways connected to three types of follicle structures in the gut-associated lymphoid tissue of a horse’s ileum.

Study Overview

The study delves into how lymph pathways in horse ileum, especially the ones present in the villi or tiny projections on the inner surface of the gut, are interconnected with prelymphatic intercellular channels. It also investigates how these pathways are linked to a network of lymphatic sinuses in the lamina propria.

  • The examination suggests that these sinuses might serve as major gateways for the migration of lymphocytes from gut-associated lymphoid tissue through the lymphatic system.
  • The vessels from the plexus penetrate the muscular layer of the mucous membrane, channeling the lymph fluid into lymphatic vessels within the interfollicular tissue.
  • This interfollicular tissue occurs between the follicles of follicle/dome structures and lymphoglandular complexes (LGCs), a part of the horse’s immune system in the digestive tract.

Lymphatic Pathways within Follicles

The research states that no lymphatic vessels emerge from the follicles, but the intercellular pathways present in the follicles are interlinked with those in the surrounding interfollicular tissue. This interconnection is further extended to the follicular sinuses located around the base of the follicles.

  • According to the study’s findings, these pathways seem to provide the only viable lymphatic route for lymphocytes leaving LGCs to enter the lymphatic system.

Deep Submucosal Lymphatic Vessels

Another pivotal discovery made in this study is that the lymph from the interfollicular tissue enters deep submucosal lymphatic vessels. These vessels are characterized by their prominent valves.

  • These deep submucosal lymphatic vessels are responsible for draining into others, which then carry the lymph from the surface of the ileum.

In conclusion, this study enhances our understanding of the lymphatic system in the horse ileum by exposing the associations between different lymphatic pathways and follicle structures present in the gut-associated lymphoid tissue. Understanding these interactions is essential for improving veterinary treatments related to the lymphatic system.

Cite This Article

APA
Lowden S, Heath T. (1996). Lymph pathways associated with three types of follicle structure found in gut-associated lymphoid tissue of horse ileum. Anat Embryol (Berl), 193(2), 175-179. https://doi.org/10.1007/BF00214708

Publication

Anatomy and embryology
ISSN: 0340-2061
NlmUniqueID: 7505194
Country: Germany
Language: English
Volume: 193
Issue: 2
Pages: 175-179

Researcher Affiliations

Lowden, S
  • Department of Anatomical Sciences, University of Queensland, Brisbane, Australia.
Heath, T

    MeSH Terms

    • Animals
    • Horses / anatomy & histology
    • Ileum / anatomy & histology
    • Lymphatic System / anatomy & histology
    • Lymphoid Tissue / anatomy & histology
    • Microscopy, Electron
    • Microscopy, Electron, Scanning

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    Citations

    This article has been cited 1 times.
    1. Diana A, Freccero F, Giancola F, Linta N, Pietra M, Luca V, Salamanca G, Cipone M, Chiocchetti R. Ex vivo ultrasonographic and histological morphometry of small intestinal wall layers in horses.. Vet Radiol Ultrasound 2022 May;63(3):353-363.
      doi: 10.1111/vru.13059pubmed: 35171532google scholar: lookup
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