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Animal reproduction science2008; 115(1-4); 110-123; doi: 10.1016/j.anireprosci.2008.12.014

Maternal age and parity influence ultrasonographic measurements of fetal growth in Dutch Warmblood mares.

Abstract: Ultrasonographic examination of the equine fetus in mid-late gestation is usually performed only if there are concerns about fetal or maternal health. Even then it is difficult to determine whether development is 'normal' for gestational age because the reference values include considerable error margins. This study examined maternal factors that influence fetal growth with the aim of producing more precise late gestation fetal growth curves for Dutch Warmblood horses. Fetal development was monitored at 2-week intervals from day 100 of gestation until term in 32 mares ranging from 4 to 18 years in age; seven of the mares were primiparous. Transrectal and/or transabdominal ultrasonographic measurement of the fetal eye orbit, cranium, aorta, heart rate and of the combined thickness of uterus and placenta (CTUP) were performed using a portable ultrasound machine equipped with 6 MHz linear and 3.5 MHz curved array probes. During days 100-250 of gestation, the CTUP was thicker in primiparous than multiparous mares (p<0.05). After day 220 the maximum cross-sectional area, but not diameter, of both the eye orbit and cranium were also greater in primiparous than multiparous mares (p<0.05). Fetal aorta diameter was not influenced by parity but was affected by maternal age, being smaller in mares > or =15 years of age than younger animals (p<0.05). Only biparietal cross-sectional surface area and aorta diameter increased linearly throughout late gestation. However, even allowing for the effects of parity and maternal age, the late gestational variation in fetal size is such that serial measurements may be required to definitively identify abnormal development.
Publication Date: 2008-12-24 PubMed ID: 19157730DOI: 10.1016/j.anireprosci.2008.12.014Google Scholar: Lookup
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  • Journal Article

Summary

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The research article observes how various factors, including the age and parity of Dutch Warmblood mares, influence the growth of the fetus as detected via ultrasound examinations. It implies that fetus growth in these horses in late gestation may require continuous measuring due to various influencing factors.

Study Objective and Method

  • To understand the influence of different maternal factors on fetal growth, the researchers observed the development of fetuses in 32 Dutch Warmblood mares through regular fortnightly ultrasounds from the 100th day of gestation until giving birth. The mares ranged from 4 to 18 years in age and included seven first-time mothers.
  • Various fetal measures like the eye orbit, skull, aorta, and heart rate were taken along the combined thickness of the uterus and placenta (CTUP) with the help of a portable ultrasound machine equipped with a 6 MHz linear and a 3.5 MHz curved array probe.

Observations and Findings

  • During the 100th to 250th day of gestation, primiparous (first-time mothers) mares had thicker CTUP than multiparous mares (those that have given birth two or more times).
  • After the 220th day, the maximum cross-sectional area of both the eye orbit and the skull was found to be larger in first-time mother mares compared to those mares who have previously given birth. However, the diameter remained unaffected by such divisions.
  • The diameter of the fetal aorta was not affected by whether it was the mare’s first or subsequent pregnancy, but it was affected by the mare’s age. In mares that were 15 years old or more, the aorta diameter was smaller than in younger mares.
  • Despite being influenced by the age and parity of the mares, the fluctuation in the size of the fetus during late gestation is considerable. Consequently, consecutive measurements may be necessary to accurately ascertain any abnormal development.

Cite This Article

APA
Hendriks WK, Colenbrander B, van der Weijden GC, Stout TA. (2008). Maternal age and parity influence ultrasonographic measurements of fetal growth in Dutch Warmblood mares. Anim Reprod Sci, 115(1-4), 110-123. https://doi.org/10.1016/j.anireprosci.2008.12.014

Publication

ISSN: 1873-2232
NlmUniqueID: 7807205
Country: Netherlands
Language: English
Volume: 115
Issue: 1-4
Pages: 110-123

Researcher Affiliations

Hendriks, W K
  • Utrecht University, Faculty of Veterinary Medicine, Department of Equine Sciences, Yalelaan 114, 3584 CM Utrecht, The Netherlands. W.K.Hendriks@uu.nl
Colenbrander, B
    van der Weijden, G C
      Stout, T A E

        MeSH Terms

        • Allantois / physiology
        • Animals
        • Eye / embryology
        • Female
        • Fetal Development
        • Gestational Age
        • Heart Rate, Fetal / physiology
        • Horses
        • Maternal Age
        • Netherlands
        • Parity
        • Postpartum Period / physiology
        • Pregnancy
        • Ultrasonography, Prenatal / veterinary

        Citations

        This article has been cited 6 times.
        1. Ali A, Derar DR, Alaeyeari AA, Alharbi YM. Fetometry in Arabian horses. Front Vet Sci 2025;12:1689769.
          doi: 10.3389/fvets.2025.1689769pubmed: 41209474google scholar: lookup
        2. Del Prete C, Vastolo A, Pasolini MP, Cocchia N, Montano C, Cutrignelli MI. Effects of maternal dietary supplementation with antioxidants on clinical status of mares and their foal. BMC Vet Res 2024 Sep 11;20(1):404.
          doi: 10.1186/s12917-024-04252-zpubmed: 39256763google scholar: lookup
        3. Abdelnaby EA, Emam IA, El-Sherbiny HR, Fadl AM. The effects of aging and gestational month on uteroplacental vascular perfusion, and umbilical artery hemodynamics in pregnant jennies. BMC Vet Res 2022 Nov 15;18(1):404.
          doi: 10.1186/s12917-022-03499-8pubmed: 36380376google scholar: lookup
        4. Gorissen BMC, Wolschrijn CF, Serra Bragança FM, Geerts AAJ, Leenders WOJL, Back W, van Weeren PR. The development of locomotor kinetics in the foal and the effect of osteochondrosis. Equine Vet J 2017 Jul;49(4):467-474.
          doi: 10.1111/evj.12649pubmed: 27859501google scholar: lookup
        5. Gorissen BM, Wolschrijn CF, van Vilsteren AA, van Rietbergen B, van Weeren PR. Trabecular bone of precocials at birth; Are they prepared to run for the wolf(f)?. J Morphol 2016 Jul;277(7):948-56.
          doi: 10.1002/jmor.20548pubmed: 27098190google scholar: lookup
        6. Murase H, Endo Y, Tsuchiya T, Kotoyori Y, Shikichi M, Ito K, Sato F, Nambo Y. Ultrasonographic evaluation of equine fetal growth throughout gestation in normal mares using a convex transducer. J Vet Med Sci 2014 Jul;76(7):947-53.
          doi: 10.1292/jvms.13-0259pubmed: 24662520google scholar: lookup